AU517287B2 - Carbohydrate derivatives of milbemycin and processes therefor - Google Patents

Carbohydrate derivatives of milbemycin and processes therefor

Info

Publication number
AU517287B2
AU517287B2 AU34760/78A AU3476078A AU517287B2 AU 517287 B2 AU517287 B2 AU 517287B2 AU 34760/78 A AU34760/78 A AU 34760/78A AU 3476078 A AU3476078 A AU 3476078A AU 517287 B2 AU517287 B2 AU 517287B2
Authority
AU
Australia
Prior art keywords
milbemycin
carbohydrate derivatives
processes therefor
therefor
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU34760/78A
Other versions
AU3476078A (en
Inventor
M. H. & Tolman R. L Fisher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/786,157 external-priority patent/US4134973A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU3476078A publication Critical patent/AU3476078A/en
Application granted granted Critical
Publication of AU517287B2 publication Critical patent/AU517287B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
AU34760/78A 1977-04-11 1978-04-04 Carbohydrate derivatives of milbemycin and processes therefor Expired AU517287B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/786,157 US4134973A (en) 1977-04-11 1977-04-11 Carbohydrate derivatives of milbemycin and processes therefor
USUS786157 1977-04-11
USUS852403 1977-11-17
US05/852,403 US4156720A (en) 1977-04-11 1977-11-17 Carbohydrate derivatives of milbemycin and processes therefor

Publications (2)

Publication Number Publication Date
AU3476078A AU3476078A (en) 1979-10-11
AU517287B2 true AU517287B2 (en) 1981-07-23

Family

ID=27120508

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34760/78A Expired AU517287B2 (en) 1977-04-11 1978-04-04 Carbohydrate derivatives of milbemycin and processes therefor

Country Status (5)

Country Link
JP (1) JPS5435293A (en)
AU (1) AU517287B2 (en)
FR (1) FR2387231A1 (en)
GB (1) GB1579118A (en)
NZ (1) NZ186851A (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
JPS59108785A (en) * 1982-11-25 1984-06-23 Sankyo Co Ltd 5-oxime derivative of milbemycins
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
JPS60126289A (en) * 1983-11-14 1985-07-05 Sankyo Co Ltd 5-carbonate derivative of milbemycin
EP0180539A1 (en) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- and 13-hydroxymilbemycin
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
EP0185623A1 (en) * 1984-12-21 1986-06-25 Ciba-Geigy Ag Milbemycin derivatives for combating insects and parasites
NZ215917A (en) * 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5114930A (en) * 1990-05-14 1992-05-19 Merck & Co., Inc. Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
NZ240150A (en) * 1990-10-15 1993-07-27 Merck & Co Inc Fermentation medium and its use in the production of ivermectin derivatives
EP0481672A1 (en) * 1990-10-15 1992-04-22 Merck & Co. Inc. 5Beta- and 13beta ivermectin monoglucopyranosides
US6214367B1 (en) 1996-06-05 2001-04-10 Ashmont Holdings Limited Injectable compositions
EP1632498A1 (en) * 2004-09-03 2006-03-08 Syngenta Participations AG Derivatives of avermectin, avermectin monosaccharide and avermectin aglycone
CN104910228B (en) * 2014-03-10 2018-12-07 浙江农林大学 Ten hexa-atomic macrolides compounds and its application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (en) * 1972-06-08 1974-02-08
SE434277B (en) * 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS

Also Published As

Publication number Publication date
NZ186851A (en) 1984-12-14
GB1579118A (en) 1980-11-12
AU3476078A (en) 1979-10-11
JPS5435293A (en) 1979-03-15
FR2387231B1 (en) 1982-05-21
FR2387231A1 (en) 1978-11-10

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