FR2387231B1 - - Google Patents

Info

Publication number
FR2387231B1
FR2387231B1 FR7810239A FR7810239A FR2387231B1 FR 2387231 B1 FR2387231 B1 FR 2387231B1 FR 7810239 A FR7810239 A FR 7810239A FR 7810239 A FR7810239 A FR 7810239A FR 2387231 B1 FR2387231 B1 FR 2387231B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7810239A
Other languages
French (fr)
Other versions
FR2387231A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/786,157 external-priority patent/US4134973A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2387231A1 publication Critical patent/FR2387231A1/en
Application granted granted Critical
Publication of FR2387231B1 publication Critical patent/FR2387231B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7810239A 1977-04-11 1978-04-06 MILBEMYCIN CARBON HYDRATE DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS ANTI-PEST AGENTS Granted FR2387231A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/786,157 US4134973A (en) 1977-04-11 1977-04-11 Carbohydrate derivatives of milbemycin and processes therefor
US05/852,403 US4156720A (en) 1977-04-11 1977-11-17 Carbohydrate derivatives of milbemycin and processes therefor

Publications (2)

Publication Number Publication Date
FR2387231A1 FR2387231A1 (en) 1978-11-10
FR2387231B1 true FR2387231B1 (en) 1982-05-21

Family

ID=27120508

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7810239A Granted FR2387231A1 (en) 1977-04-11 1978-04-06 MILBEMYCIN CARBON HYDRATE DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS ANTI-PEST AGENTS

Country Status (5)

Country Link
JP (1) JPS5435293A (en)
AU (1) AU517287B2 (en)
FR (1) FR2387231A1 (en)
GB (1) GB1579118A (en)
NZ (1) NZ186851A (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
JPS59108785A (en) * 1982-11-25 1984-06-23 Sankyo Co Ltd 5-oxime derivative of milbemycins
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
JPS60126289A (en) * 1983-11-14 1985-07-05 Sankyo Co Ltd 5-carbonate derivative of milbemycin
EP0180539A1 (en) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- and 13-hydroxymilbemycin
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
EP0185623A1 (en) * 1984-12-21 1986-06-25 Ciba-Geigy Ag Milbemycin derivatives for combating insects and parasites
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
NZ215917A (en) * 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5114930A (en) * 1990-05-14 1992-05-19 Merck & Co., Inc. Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
NZ240150A (en) * 1990-10-15 1993-07-27 Merck & Co Inc Fermentation medium and its use in the production of ivermectin derivatives
EP0481672A1 (en) * 1990-10-15 1992-04-22 Merck & Co. Inc. 5Beta- and 13beta ivermectin monoglucopyranosides
AU728221B2 (en) 1996-06-05 2001-01-04 Ashmont Holdings Limited Injectable compositions
EP1632498A1 (en) * 2004-09-03 2006-03-08 Syngenta Participations AG Derivatives of avermectin, avermectin monosaccharide and avermectin aglycone
CN104910228B (en) * 2014-03-10 2018-12-07 浙江农林大学 Ten hexa-atomic macrolides compounds and its application

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (en) * 1972-06-08 1974-02-08
SE434277B (en) * 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS

Also Published As

Publication number Publication date
JPS5435293A (en) 1979-03-15
AU3476078A (en) 1979-10-11
GB1579118A (en) 1980-11-12
AU517287B2 (en) 1981-07-23
FR2387231A1 (en) 1978-11-10
NZ186851A (en) 1984-12-14

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Legal Events

Date Code Title Description
ST Notification of lapse