ZA77195B - Improvements in or relating to the manufacture of semi-synthetic penicillin antibiotics - Google Patents

Improvements in or relating to the manufacture of semi-synthetic penicillin antibiotics

Info

Publication number
ZA77195B
ZA77195B ZA770195A ZA77195A ZA77195B ZA 77195 B ZA77195 B ZA 77195B ZA 770195 A ZA770195 A ZA 770195A ZA 77195 A ZA77195 A ZA 77195A ZA 77195 B ZA77195 B ZA 77195B
Authority
ZA
South Africa
Prior art keywords
relating
semi
manufacture
penicillin antibiotics
synthetic penicillin
Prior art date
Application number
ZA770195A
Inventor
M Croci
G Cotti
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of ZA77195B publication Critical patent/ZA77195B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • C07D499/10Modification of an amino radical directly attached in position 6
    • C07D499/12Acylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
ZA770195A 1976-01-15 1977-01-14 Improvements in or relating to the manufacture of semi-synthetic penicillin antibiotics ZA77195B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47643/76A IT1053313B (en) 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS

Publications (1)

Publication Number Publication Date
ZA77195B true ZA77195B (en) 1977-11-30

Family

ID=11261624

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA770195A ZA77195B (en) 1976-01-15 1977-01-14 Improvements in or relating to the manufacture of semi-synthetic penicillin antibiotics

Country Status (14)

Country Link
JP (1) JPS5287191A (en)
AU (1) AU512150B2 (en)
BE (1) BE850382A (en)
CH (1) CH627182A5 (en)
DE (1) DE2701406A1 (en)
DK (1) DK13977A (en)
ES (1) ES455026A1 (en)
FR (1) FR2338279A1 (en)
GB (1) GB1569427A (en)
IT (1) IT1053313B (en)
NL (1) NL7700396A (en)
SE (1) SE437989B (en)
YU (1) YU9277A (en)
ZA (1) ZA77195B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB958478A (en) * 1962-03-13 1964-05-21 Beecham Res Lab Production of penicillins
FR68F (en) * 1962-10-17
US3351597A (en) * 1966-11-23 1967-11-07 Lilly Co Eli Process for acylating 7-amino cephalosporanic acid
ZA695612B (en) * 1968-08-23 1971-03-31 Lilly Co Eli Preparation of cephalosporin compounds
US3595855A (en) * 1968-12-05 1971-07-27 American Home Prod Process for producing aminopenicillins
IT1043957B (en) * 1970-12-31 1980-02-29 Lorenzini Sas Inst Biochim PROCESS FOR THE PREPARATION OF THE ANHYDROUS FORM OF ACID 6, D, LESS ALPINE AMINOPHENYLACETAMIDE PENICILLANIC
GB1494902A (en) * 1974-05-09 1977-12-14 Glaxo Lab Ltd Penicillins
IT1039495B (en) * 1975-06-26 1979-12-10 Dobfar Spa PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC SUBSTANCES

Also Published As

Publication number Publication date
NL7700396A (en) 1977-07-19
ES455026A1 (en) 1977-12-16
JPS5287191A (en) 1977-07-20
DK13977A (en) 1977-07-16
AU512150B2 (en) 1980-09-25
CH627182A5 (en) 1981-12-31
FR2338279B1 (en) 1980-09-05
FR2338279A1 (en) 1977-08-12
SE437989B (en) 1985-03-25
YU9277A (en) 1982-06-30
BE850382A (en) 1977-07-14
DE2701406A1 (en) 1977-07-21
AU2134077A (en) 1978-07-20
SE7700393L (en) 1977-07-16
GB1569427A (en) 1980-06-18
IT1053313B (en) 1981-08-31

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