IT1053313B - PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS - Google Patents

PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS

Info

Publication number
IT1053313B
IT1053313B IT47643/76A IT4764376A IT1053313B IT 1053313 B IT1053313 B IT 1053313B IT 47643/76 A IT47643/76 A IT 47643/76A IT 4764376 A IT4764376 A IT 4764376A IT 1053313 B IT1053313 B IT 1053313B
Authority
IT
Italy
Prior art keywords
procedure
producing semi
synthetic antibiotics
antibiotics
synthetic
Prior art date
Application number
IT47643/76A
Other languages
Italian (it)
Inventor
M Croci
G Cotti
Original Assignee
Ankerfarm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ankerfarm Spa filed Critical Ankerfarm Spa
Priority to IT47643/76A priority Critical patent/IT1053313B/en
Priority to CH43377A priority patent/CH627182A5/en
Priority to DK13977A priority patent/DK13977A/en
Priority to ZA770195A priority patent/ZA77195B/en
Priority to YU00092/77A priority patent/YU9277A/en
Priority to DE19772701406 priority patent/DE2701406A1/en
Priority to BE174079A priority patent/BE850382A/en
Priority to GB1542/77A priority patent/GB1569427A/en
Priority to JP252077A priority patent/JPS5287191A/en
Priority to FR7701123A priority patent/FR2338279A1/en
Priority to AU21340/77A priority patent/AU512150B2/en
Priority to ES455026A priority patent/ES455026A1/en
Priority to SE7700393A priority patent/SE437989B/en
Priority to NL7700396A priority patent/NL7700396A/en
Priority to US05/914,287 priority patent/US4181656A/en
Application granted granted Critical
Publication of IT1053313B publication Critical patent/IT1053313B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/10—Modification of an amino radical directly attached in position 6
    • C07D499/12—Acylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
IT47643/76A 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS IT1053313B (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT47643/76A IT1053313B (en) 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS
CH43377A CH627182A5 (en) 1976-01-15 1977-01-13 Process for the preparation of semisynthetic penicillin antibiotics
FR7701123A FR2338279A1 (en) 1976-01-15 1977-01-14 PERFECTIONS RELATED TO THE MANUFACTURE OF ANTIBIOTICS OF THE PENICILLIN TYPE, SEMI-YXNTHETICS
YU00092/77A YU9277A (en) 1976-01-15 1977-01-14 Process for producing anthibiotics of 6-acylaminopenicillanic acid
DE19772701406 DE2701406A1 (en) 1976-01-15 1977-01-14 METHOD FOR MANUFACTURING SEMI-SYNTHETIC PENICILLIN ANTIBIOTICS
BE174079A BE850382A (en) 1976-01-15 1977-01-14 IMPROVEMENTS IN THE MANUFACTURE OF ANTIBIOTICS OF THE PENICILLIN TYPE
DK13977A DK13977A (en) 1976-01-15 1977-01-14 PROCEDURE FOR THE PREPARATION OF SALM SYNTHETIC PENICILLINANTIBIOTICS
JP252077A JPS5287191A (en) 1976-01-15 1977-01-14 Process for preparing semiisynthetic penicillin antibiotics
ZA770195A ZA77195B (en) 1976-01-15 1977-01-14 Improvements in or relating to the manufacture of semi-synthetic penicillin antibiotics
AU21340/77A AU512150B2 (en) 1976-01-15 1977-01-14 Penicillin manufacture
ES455026A ES455026A1 (en) 1976-01-15 1977-01-14 Manufacture of semi-synthetic penicillin antibiotics
SE7700393A SE437989B (en) 1976-01-15 1977-01-14 PROCEDURE FOR PREPARING 6-ACYLAMINOPENICILLANIC ACID
NL7700396A NL7700396A (en) 1976-01-15 1977-01-14 IMPROVEMENTS IN AND RELATING TO THE PREPARATION OF SEMI-SYNTHETIC PENICILLIN ANTIBIOTIC.
GB1542/77A GB1569427A (en) 1976-01-15 1977-01-14 Manufacture of semi-synthetic penicillin antibiotics
US05/914,287 US4181656A (en) 1976-01-15 1978-06-09 Manufacture of semi-synthetic penicillin antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47643/76A IT1053313B (en) 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS

Publications (1)

Publication Number Publication Date
IT1053313B true IT1053313B (en) 1981-08-31

Family

ID=11261624

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47643/76A IT1053313B (en) 1976-01-15 1976-01-15 PROCEDURE FOR PRODUCING SEMI-SYNTHETIC ANTIBIOTICS

Country Status (14)

Country Link
JP (1) JPS5287191A (en)
AU (1) AU512150B2 (en)
BE (1) BE850382A (en)
CH (1) CH627182A5 (en)
DE (1) DE2701406A1 (en)
DK (1) DK13977A (en)
ES (1) ES455026A1 (en)
FR (1) FR2338279A1 (en)
GB (1) GB1569427A (en)
IT (1) IT1053313B (en)
NL (1) NL7700396A (en)
SE (1) SE437989B (en)
YU (1) YU9277A (en)
ZA (1) ZA77195B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB958478A (en) * 1962-03-13 1964-05-21 Beecham Res Lab Production of penicillins
BE638819A (en) * 1962-10-17
US3351597A (en) * 1966-11-23 1967-11-07 Lilly Co Eli Process for acylating 7-amino cephalosporanic acid
ZA695612B (en) * 1968-08-23 1971-03-31 Lilly Co Eli Preparation of cephalosporin compounds
US3595855A (en) * 1968-12-05 1971-07-27 American Home Prod Process for producing aminopenicillins
IT1043957B (en) * 1970-12-31 1980-02-29 Lorenzini Sas Inst Biochim PROCESS FOR THE PREPARATION OF THE ANHYDROUS FORM OF ACID 6, D, LESS ALPINE AMINOPHENYLACETAMIDE PENICILLANIC
GB1494902A (en) * 1974-05-09 1977-12-14 Glaxo Lab Ltd Penicillins
IT1039495B (en) * 1975-06-26 1979-12-10 Dobfar Spa PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC SUBSTANCES

Also Published As

Publication number Publication date
DK13977A (en) 1977-07-16
FR2338279A1 (en) 1977-08-12
YU9277A (en) 1982-06-30
AU512150B2 (en) 1980-09-25
BE850382A (en) 1977-07-14
NL7700396A (en) 1977-07-19
ES455026A1 (en) 1977-12-16
CH627182A5 (en) 1981-12-31
SE437989B (en) 1985-03-25
AU2134077A (en) 1978-07-20
DE2701406A1 (en) 1977-07-21
JPS5287191A (en) 1977-07-20
ZA77195B (en) 1977-11-30
FR2338279B1 (en) 1980-09-05
SE7700393L (en) 1977-07-16
GB1569427A (en) 1980-06-18

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