ZA767465B - Prostaglandin analogs - Google Patents
Prostaglandin analogsInfo
- Publication number
- ZA767465B ZA767465B ZA767465A ZA767465A ZA767465B ZA 767465 B ZA767465 B ZA 767465B ZA 767465 A ZA767465 A ZA 767465A ZA 767465 A ZA767465 A ZA 767465A ZA 767465 B ZA767465 B ZA 767465B
- Authority
- ZA
- South Africa
- Prior art keywords
- prostaglandin analogs
- prostaglandin
- analogs
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/647,357 US4055602A (en) | 1976-01-08 | 1976-01-08 | 2-Decarboxy-2-hydroxy-methyl-5-oxa-17-phenyl-18,19,20-trinor-PGF-analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA767465B true ZA767465B (en) | 1977-11-30 |
Family
ID=24596656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA767465A ZA767465B (en) | 1976-01-08 | 1976-12-15 | Prostaglandin analogs |
Country Status (9)
| Country | Link |
|---|---|
| US (20) | US4055602A (de) |
| JP (1) | JPS5289649A (de) |
| AU (1) | AU502587B2 (de) |
| BE (1) | BE850204A (de) |
| CH (1) | CH627725A5 (de) |
| DE (1) | DE2659215A1 (de) |
| FR (1) | FR2337712A1 (de) |
| NL (1) | NL7700117A (de) |
| ZA (1) | ZA767465B (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4183870A (en) * | 1974-01-26 | 1980-01-15 | May & Baker Limited | Cyclopentane derivatives |
| US4048058A (en) * | 1975-08-13 | 1977-09-13 | Standard Oil Company (Indiana) | Methods to be used in reforming processes employing multi-metallic catalysts |
| US4208538A (en) * | 1976-01-08 | 1980-06-17 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-3,7-inter-m-phenylene-ω-phenyl-PGF2 compounds |
| US4638100A (en) * | 1976-01-08 | 1987-01-20 | The Upjohn Company | Aromatic or inter-oxa 2-decarboxy-2-hydroxymethyl-PGFα compounds |
| DE2655004C3 (de) * | 1976-12-02 | 1980-06-19 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von bicyclischen Laktonen |
| US5030621A (en) * | 1987-04-23 | 1991-07-09 | Bystryn Jean Claude | Shed melanoma antigen compositions |
| US5972991A (en) | 1992-09-21 | 1999-10-26 | Allergan | Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5688819A (en) * | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US20030060878A1 (en) | 2001-08-31 | 2003-03-27 | Shadduck John H. | Intraocular lens system and method for power adjustment |
| US8048155B2 (en) | 2002-02-02 | 2011-11-01 | Powervision, Inc. | Intraocular implant devices |
| US7217288B2 (en) | 2002-12-12 | 2007-05-15 | Powervision, Inc. | Accommodating intraocular lens having peripherally actuated deflectable surface and method |
| US8328869B2 (en) | 2002-12-12 | 2012-12-11 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
| US7637947B2 (en) | 2002-12-12 | 2009-12-29 | Powervision, Inc. | Accommodating intraocular lens system having spherical aberration compensation and method |
| US8361145B2 (en) | 2002-12-12 | 2013-01-29 | Powervision, Inc. | Accommodating intraocular lens system having circumferential haptic support and method |
| US10835373B2 (en) | 2002-12-12 | 2020-11-17 | Alcon Inc. | Accommodating intraocular lenses and methods of use |
| WO2004081613A2 (en) | 2003-03-06 | 2004-09-23 | Shadduck John H | Adaptive optic lens and method of making |
| US7306580B2 (en) * | 2003-04-16 | 2007-12-11 | Cook Incorporated | Medical device with therapeutic agents |
| CN1984839A (zh) | 2004-03-24 | 2007-06-20 | H.C.施塔克公司 | 形成具有可控和新型微观结构的α和β钽薄膜的方法 |
| US20060292324A1 (en) * | 2004-03-26 | 2006-12-28 | Robert Roberts | Uniaxially and biaxially-oriented polytetrafluoroethylene structures |
| US7906552B2 (en) * | 2004-08-10 | 2011-03-15 | Allergan, Inc. | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| US7183310B2 (en) * | 2004-08-10 | 2007-02-27 | Allergan, Inc. | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| US9872763B2 (en) | 2004-10-22 | 2018-01-23 | Powervision, Inc. | Accommodating intraocular lenses |
| WO2010102078A1 (en) | 2009-03-04 | 2010-09-10 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| WO2008103798A2 (en) | 2007-02-21 | 2008-08-28 | Powervision, Inc. | Polymeric materials suitable for ophthalmic devices and methods of manufacture |
| AU2008279167B2 (en) | 2007-07-23 | 2014-10-09 | Alcon Inc. | Post-implant lens power modification |
| JP5426547B2 (ja) | 2007-07-23 | 2014-02-26 | パワーヴィジョン・インコーポレーテッド | レンズ送出システム |
| US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
| US8314927B2 (en) * | 2007-07-23 | 2012-11-20 | Powervision, Inc. | Systems and methods for testing intraocular lenses |
| WO2009015226A2 (en) | 2007-07-23 | 2009-01-29 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
| US10299913B2 (en) | 2009-01-09 | 2019-05-28 | Powervision, Inc. | Accommodating intraocular lenses and methods of use |
| CA2768154C (en) | 2009-07-13 | 2018-02-13 | Irix Pharmaceuticals | Synthesis of prostanoids |
| EP2473138A4 (de) * | 2009-08-31 | 2017-08-16 | PowerVision, Inc. | Schätzung der linsenkapselgrösse |
| US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
| JP2013520291A (ja) | 2010-02-23 | 2013-06-06 | パワーヴィジョン・インコーポレーテッド | 遠近調節型眼内レンズのための液体 |
| WO2012006616A2 (en) | 2010-07-09 | 2012-01-12 | Powervision, Inc. | Intraocular lens delivery devices and methods of use |
| ES2875049T3 (es) | 2011-03-24 | 2021-11-08 | Alcon Inc | Sistemas de carga de lentes intraoculares y métodos de uso |
| US10433949B2 (en) | 2011-11-08 | 2019-10-08 | Powervision, Inc. | Accommodating intraocular lenses |
| JP6717740B2 (ja) | 2013-03-15 | 2020-07-01 | パワーヴィジョン・インコーポレーテッド | 眼内レンズの収容および載置装置ならびにその使用方法 |
| JP6488472B2 (ja) | 2013-09-30 | 2019-03-27 | パテオン エーピーアイ サービシーズ インコーポレイテッドＰａｔｈｅｏｎ Ａｐｉ Ｓｅｒｖｉｃｅｓ Ｉｎｃ． | メタセシスを用いるプロスタグランジンおよびプロスタグランジン中間体の新規合成経路 |
| AU2016349532B2 (en) | 2015-11-06 | 2021-08-26 | Alcon Inc. | Accommodating intraocular lenses and methods of manufacturing |
| CN114650789A (zh) | 2019-10-04 | 2022-06-21 | 爱尔康公司 | 可调节眼内透镜及术后调节眼内透镜的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3959346A (en) * | 1969-03-14 | 1976-05-25 | The Upjohn Company | Racemic prostaglandins of the 2-series and analogs thereof |
| DE2317019A1 (de) * | 1972-04-27 | 1973-11-08 | Upjohn Co | Neue 4,5-didehydro-prostaglandine |
| US3914282A (en) * | 1973-01-16 | 1975-10-21 | Upjohn Co | Prostaglandin E{HD 1{B , F{HD 1{B , and A{HD 1 {B analogs |
| US3962293A (en) * | 1973-07-20 | 1976-06-08 | The Upjohn Company | 13,14-Dihydro-16-fluoro prostaglandin F1 |
| US3932463A (en) * | 1974-06-03 | 1976-01-13 | American Cyanamid Company | 11-Deoxy-13-dihydro-prostaglandin-9-ketals |
-
1976
- 1976-01-08 US US05/647,357 patent/US4055602A/en not_active Expired - Lifetime
- 1976-12-15 ZA ZA767465A patent/ZA767465B/xx unknown
- 1976-12-16 CH CH1586776A patent/CH627725A5/de not_active IP Right Cessation
- 1976-12-21 AU AU20771/76A patent/AU502587B2/en not_active Expired
- 1976-12-28 DE DE19762659215 patent/DE2659215A1/de not_active Withdrawn
-
1977
- 1977-01-07 BE BE173933A patent/BE850204A/xx not_active IP Right Cessation
- 1977-01-07 NL NL7700117A patent/NL7700117A/xx not_active Application Discontinuation
- 1977-01-07 JP JP44377A patent/JPS5289649A/ja active Pending
- 1977-01-07 FR FR7700428A patent/FR2337712A1/fr active Granted
- 1977-08-05 US US05/822,034 patent/US4107216A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,038 patent/US4110383A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,305 patent/US4113778A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,020 patent/US4108900A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,031 patent/US4107215A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,027 patent/US4107214A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,301 patent/US4110384A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,035 patent/US4110382A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,303 patent/US4111996A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,024 patent/US4115454A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,302 patent/US4107213A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,026 patent/US4110381A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,037 patent/US4108903A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,023 patent/US4108901A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,033 patent/US4107212A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,025 patent/US4108902A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,299 patent/US4111995A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,036 patent/US4127733A/en not_active Expired - Lifetime
- 1977-08-05 US US05/822,300 patent/US4107211A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2077176A (en) | 1978-06-29 |
| NL7700117A (nl) | 1977-07-12 |
| DE2659215A1 (de) | 1977-07-21 |
| US4108903A (en) | 1978-08-22 |
| AU502587B2 (en) | 1979-08-02 |
| US4107214A (en) | 1978-08-15 |
| JPS5289649A (en) | 1977-07-27 |
| US4108902A (en) | 1978-08-22 |
| US4108901A (en) | 1978-08-22 |
| US4055602A (en) | 1977-10-25 |
| US4110381A (en) | 1978-08-29 |
| US4108900A (en) | 1978-08-22 |
| US4111995A (en) | 1978-09-05 |
| FR2337712B1 (de) | 1983-05-20 |
| US4107215A (en) | 1978-08-15 |
| US4110382A (en) | 1978-08-29 |
| US4115454A (en) | 1978-09-19 |
| US4107212A (en) | 1978-08-15 |
| US4107211A (en) | 1978-08-15 |
| US4111996A (en) | 1978-09-05 |
| US4110384A (en) | 1978-08-29 |
| FR2337712A1 (fr) | 1977-08-05 |
| US4127733A (en) | 1978-11-28 |
| US4107213A (en) | 1978-08-15 |
| CH627725A5 (de) | 1982-01-29 |
| US4113778A (en) | 1978-09-12 |
| US4110383A (en) | 1978-08-29 |
| US4107216A (en) | 1978-08-15 |
| BE850204A (fr) | 1977-07-07 |
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