ZA767416B - Prostaglandin analogs - Google Patents
Prostaglandin analogsInfo
- Publication number
- ZA767416B ZA767416B ZA767416A ZA767416A ZA767416B ZA 767416 B ZA767416 B ZA 767416B ZA 767416 A ZA767416 A ZA 767416A ZA 767416 A ZA767416 A ZA 767416A ZA 767416 B ZA767416 B ZA 767416B
- Authority
- ZA
- South Africa
- Prior art keywords
- prostaglandin analogs
- prostaglandin
- analogs
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64527675A | 1975-12-29 | 1975-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA767416B true ZA767416B (en) | 1977-11-30 |
Family
ID=24588384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA767416A ZA767416B (en) | 1975-12-29 | 1976-12-13 | Prostaglandin analogs |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US4122282A (xx) |
| JP (1) | JPS5283351A (xx) |
| AU (1) | AU502349B2 (xx) |
| BE (1) | BE849963A (xx) |
| CA (1) | CA1077473A (xx) |
| CH (1) | CH629747A5 (xx) |
| DE (1) | DE2658207A1 (xx) |
| ES (1) | ES454181A1 (xx) |
| FR (1) | FR2336924A1 (xx) |
| GB (2) | GB1554042A (xx) |
| HU (1) | HU178365B (xx) |
| IL (1) | IL50997A (xx) |
| MX (1) | MX4940E (xx) |
| NL (1) | NL7614389A (xx) |
| PL (1) | PL116421B1 (xx) |
| SE (1) | SE7614584L (xx) |
| SU (1) | SU731895A3 (xx) |
| ZA (1) | ZA767416B (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048058A (en) * | 1975-08-13 | 1977-09-13 | Standard Oil Company (Indiana) | Methods to be used in reforming processes employing multi-metallic catalysts |
| US4267315A (en) * | 1979-05-01 | 1981-05-12 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-11a-methano-TXA2 compounds |
| US4292445A (en) * | 1980-04-28 | 1981-09-29 | The Upjohn Company | Amide and sulfonamide derivatives of 2-decarboxy-2-aminomethyl-PG-type compounds |
| CA1241324A (en) | 1984-03-08 | 1988-08-30 | Paul A. Aristoff | Interphenylene carbacyclin derivatives |
| JPH0121948Y2 (xx) * | 1985-03-29 | 1989-06-29 | ||
| US5270049A (en) * | 1990-11-09 | 1993-12-14 | Allergan, Inc. | 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives |
| HU223068B1 (hu) * | 1995-12-20 | 2004-03-01 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Eljárás PGE1 prosztanoid előállítására |
| US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| US9241918B2 (en) | 2005-03-16 | 2016-01-26 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| WO2011008756A1 (en) | 2009-07-13 | 2011-01-20 | Irix Pharmaceuticals | Synthesis of prostanoids |
| US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
| HUP1000284A3 (en) * | 2010-06-01 | 2012-08-28 | Avidin Kft | Use of derivatives of pgf1-alpha for preparation of medicament for reducing inflammation |
| US10100028B2 (en) | 2013-09-30 | 2018-10-16 | Patheon Api Services Inc. | Synthesis routes for prostaglandins and prostaglandin intermediates using metathesis |
| CN104860860B (zh) * | 2015-04-29 | 2017-09-19 | 东北制药集团股份有限公司 | 一种卡前列酯的纯化制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2166971A (en) * | 1932-09-14 | 1939-07-25 | Ig Farbenindustrie Ag | Production of amines |
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| US3647804A (en) * | 1970-02-27 | 1972-03-07 | Upjohn Co | Cycloalkanecarboxamides |
| US3852296A (en) * | 1971-07-16 | 1974-12-03 | Richardson Merrell Spa | Mannich bases of cyclopentanones and cyclopent-2-enones and process of preparing the same |
| US3987087A (en) * | 1971-07-29 | 1976-10-19 | The Upjohn Company | Phenyl-substituted prostaglandin-f type analogs |
| US3954741A (en) * | 1972-06-07 | 1976-05-04 | Pfizer Inc. | N-substituted prostaglandin carboxamides |
| US3987085A (en) * | 1972-09-15 | 1976-10-19 | The Upjohn Company | 8β,11β,12α-PGF2.sub.α compounds |
-
1976
- 1976-08-30 US US05/719,056 patent/US4122282A/en not_active Expired - Lifetime
- 1976-08-30 US US05/719,054 patent/US4081478A/en not_active Expired - Lifetime
- 1976-08-30 US US05/719,053 patent/US4085139A/en not_active Expired - Lifetime
- 1976-08-30 US US05/719,055 patent/US4073808A/en not_active Expired - Lifetime
- 1976-11-16 CA CA265,797A patent/CA1077473A/en not_active Expired
- 1976-11-25 IL IL50997A patent/IL50997A/xx unknown
- 1976-12-09 AU AU20396/76A patent/AU502349B2/en not_active Expired
- 1976-12-13 ES ES454181A patent/ES454181A1/es not_active Expired
- 1976-12-13 ZA ZA767416A patent/ZA767416B/xx unknown
- 1976-12-15 CH CH1579476A patent/CH629747A5/de not_active IP Right Cessation
- 1976-12-21 HU HU76UO132A patent/HU178365B/hu unknown
- 1976-12-22 DE DE19762658207 patent/DE2658207A1/de not_active Withdrawn
- 1976-12-23 GB GB30065/78A patent/GB1554042A/en not_active Expired
- 1976-12-23 GB GB53739/76A patent/GB1554041A/en not_active Expired
- 1976-12-23 JP JP15439276A patent/JPS5283351A/ja active Granted
- 1976-12-24 NL NL7614389A patent/NL7614389A/xx not_active Application Discontinuation
- 1976-12-27 SE SE7614584A patent/SE7614584L/xx not_active Application Discontinuation
- 1976-12-28 SU SU762434653A patent/SU731895A3/ru active
- 1976-12-28 FR FR7639303A patent/FR2336924A1/fr active Granted
- 1976-12-29 PL PL1976194803A patent/PL116421B1/pl unknown
- 1976-12-29 BE BE173722A patent/BE849963A/xx not_active IP Right Cessation
-
1977
- 1977-01-03 MX MX775256U patent/MX4940E/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL50997A0 (en) | 1977-01-31 |
| AU502349B2 (en) | 1979-07-19 |
| SU731895A3 (ru) | 1980-04-30 |
| CH629747A5 (de) | 1982-05-14 |
| GB1554041A (en) | 1979-10-17 |
| IL50997A (en) | 1982-05-31 |
| US4081478A (en) | 1978-03-28 |
| US4085139A (en) | 1978-04-18 |
| SE7614584L (sv) | 1977-06-30 |
| ES454181A1 (es) | 1977-12-16 |
| US4122282A (en) | 1978-10-24 |
| GB1554042A (en) | 1979-10-17 |
| JPS5283351A (en) | 1977-07-12 |
| DE2658207A1 (de) | 1977-07-07 |
| BE849963A (fr) | 1977-06-29 |
| CA1077473A (en) | 1980-05-13 |
| JPS5744666B2 (xx) | 1982-09-22 |
| MX4940E (es) | 1983-01-10 |
| FR2336924B1 (xx) | 1984-08-17 |
| PL116421B1 (en) | 1981-06-30 |
| FR2336924A1 (fr) | 1977-07-29 |
| US4073808A (en) | 1978-02-14 |
| HU178365B (en) | 1982-04-28 |
| NL7614389A (nl) | 1977-07-01 |
| AU2039676A (en) | 1978-06-15 |
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