ZA757974B - Antiarrhythmia compositions and methods - Google Patents
Antiarrhythmia compositions and methodsInfo
- Publication number
- ZA757974B ZA757974B ZA00757974A ZA757974A ZA757974B ZA 757974 B ZA757974 B ZA 757974B ZA 00757974 A ZA00757974 A ZA 00757974A ZA 757974 A ZA757974 A ZA 757974A ZA 757974 B ZA757974 B ZA 757974B
- Authority
- ZA
- South Africa
- Prior art keywords
- antiarrhythmia
- compositions
- methods
- antiarrhythmia compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/536,708 US4002766A (en) | 1974-12-26 | 1974-12-26 | Antiarrhythmia methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA757974B true ZA757974B (en) | 1976-12-29 |
Family
ID=24139598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00757974A ZA757974B (en) | 1974-12-26 | 1975-12-23 | Antiarrhythmia compositions and methods |
Country Status (18)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133881A (en) * | 1977-04-27 | 1979-01-09 | A. H. Robins Company, Incorporated | Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods |
| US4242261A (en) * | 1979-07-19 | 1980-12-30 | A. H. Robins Company, Inc. | Production of methylene-cycloamines |
| US4260606A (en) * | 1979-07-19 | 1981-04-07 | A. H. Robins Company, Inc. | 3-Methyleneazetidine derivatives |
| IL76583A (en) * | 1984-10-19 | 1988-08-31 | Robins Co Inc A H | 1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them |
| US4812452A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US4812451A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha. |
| US4594343A (en) * | 1984-10-19 | 1986-06-10 | Shanklin Jr James R | 1-[(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US4810703A (en) * | 1984-10-19 | 1989-03-07 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US5932594A (en) * | 1988-11-01 | 1999-08-03 | Pfizer, Inc. | Muscarinic receptor antagonists |
| GB8825505D0 (en) * | 1988-11-01 | 1988-12-07 | Pfizer Ltd | Therapeutic agents |
| US5233053A (en) * | 1989-03-17 | 1993-08-03 | Pfizer Inc. | Pyrrolidine derivatives |
| GB8906166D0 (en) * | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
| US6693202B1 (en) | 1999-02-16 | 2004-02-17 | Theravance, Inc. | Muscarinic receptor antagonists |
| TW200800953A (en) * | 2002-10-30 | 2008-01-01 | Theravance Inc | Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine |
| EP1615881A2 (en) * | 2003-04-01 | 2006-01-18 | Theravance, Inc. | Diarylmethyl and related compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
| TW200510298A (en) | 2003-06-13 | 2005-03-16 | Theravance Inc | Substituted pyrrolidine and related compounds |
| US7368463B2 (en) * | 2003-07-11 | 2008-05-06 | Theravance, Inc. | Substituted 4-amino-1-benzylpiperidine compounds |
| JP2007528418A (ja) * | 2004-03-11 | 2007-10-11 | セラヴァンス， インコーポレーテッド | ムスカリンレセプターアンタゴニストとしての有用なジフェニルメチル化合物 |
| WO2005087722A1 (en) * | 2004-03-11 | 2005-09-22 | Theravance, Inc. | Diphenylmethyl compounds useful as muscarinic receptor antagonists |
| TW200540154A (en) * | 2004-06-10 | 2005-12-16 | Theravance Inc | Crystalline form of a substituted pyrrolidine compound |
| CA2626715A1 (en) * | 2005-12-27 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Processes for preparing darifenacin hydrobromide |
| BRPI0807615A8 (pt) * | 2007-02-23 | 2017-12-05 | Theravance Inc | Compostos de difenilmetil amônico quaternário úteis como antagonistas de receptor muscarínico |
| ES2425592T3 (es) | 2007-04-24 | 2013-10-16 | Theravance, Inc. | Compuestos de amonio cuaternario de utilidad como antagonistas de los receptores muscarínicos |
| WO2012166909A1 (en) * | 2011-06-03 | 2012-12-06 | Galleon Pharmaceuticals, Inc. | Compositions and methods for treating breathing control disorders or diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3192210A (en) * | 1961-12-04 | 1965-06-29 | Robins Co Inc A H | 4-(omega-substituted alkyl)-3, 3-disubstituted-1-substituted-2-pyrrolidinones and 4-(omega-substituted alkyl)-3, 3-disubstituted-1-substituted-2-thionpyrrolidinones |
| US3466321A (en) * | 1965-05-17 | 1969-09-09 | Ucb Sa | Derivatives of phenyl-acetic acid |
| US3878217A (en) * | 1972-01-28 | 1975-04-15 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
-
1974
- 1974-12-26 US US05/536,708 patent/US4002766A/en not_active Expired - Lifetime
-
1975
- 1975-12-15 AU AU87549/75A patent/AU498763B2/en not_active Expired
- 1975-12-18 SE SE7514375A patent/SE428126B/xx not_active IP Right Cessation
- 1975-12-19 FI FI753607A patent/FI753607A/fi not_active Application Discontinuation
- 1975-12-22 CH CH1660475A patent/CH619932A5/fr not_active IP Right Cessation
- 1975-12-22 BE BE163037A patent/BE836974A/xx not_active IP Right Cessation
- 1975-12-23 FR FR7539571A patent/FR2295745A1/fr active Granted
- 1975-12-23 ZA ZA00757974A patent/ZA757974B/xx unknown
- 1975-12-23 DK DK589175AA patent/DK137751B/da not_active IP Right Cessation
- 1975-12-23 GB GB52610/75A patent/GB1535770A/en not_active Expired
- 1975-12-23 NO NO754377A patent/NO754377L/no unknown
- 1975-12-23 CA CA242,431A patent/CA1055396A/en not_active Expired
- 1975-12-23 IE IE2823/75A patent/IE43901B1/en unknown
- 1975-12-24 DE DE19752558501 patent/DE2558501A1/de active Granted
- 1975-12-24 PH PH17925A patent/PH13483A/en unknown
- 1975-12-24 ES ES443846A patent/ES443846A1/es not_active Expired
- 1975-12-24 NL NLAANVRAGE7515071,A patent/NL185620C/xx not_active IP Right Cessation
- 1975-12-26 JP JP50159798A patent/JPS5191255A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2558501A1 (de) | 1976-07-08 |
| CA1055396A (en) | 1979-05-29 |
| FI753607A (US07655688-20100202-C00086.png) | 1976-06-27 |
| US4002766A (en) | 1977-01-11 |
| DK589175A (US07655688-20100202-C00086.png) | 1976-06-27 |
| BE836974A (fr) | 1976-04-16 |
| CH619932A5 (US07655688-20100202-C00086.png) | 1980-10-31 |
| NL185620B (nl) | 1990-01-02 |
| IE43901B1 (en) | 1981-07-01 |
| FR2295745A1 (fr) | 1976-07-23 |
| JPS612658B2 (US07655688-20100202-C00086.png) | 1986-01-27 |
| SE428126B (sv) | 1983-06-06 |
| IE43901L (en) | 1976-06-26 |
| DE2558501C2 (US07655688-20100202-C00086.png) | 1987-07-16 |
| PH13483A (en) | 1980-05-21 |
| NO754377L (US07655688-20100202-C00086.png) | 1976-06-29 |
| NL185620C (nl) | 1990-06-01 |
| ES443846A1 (es) | 1977-07-16 |
| FR2295745B1 (US07655688-20100202-C00086.png) | 1980-06-27 |
| DK137751B (da) | 1978-05-01 |
| AU8754975A (en) | 1977-06-23 |
| GB1535770A (en) | 1978-12-13 |
| JPS5191255A (en) | 1976-08-10 |
| NL7515071A (nl) | 1976-06-29 |
| AU498763B2 (en) | 1979-03-22 |
| DK137751C (US07655688-20100202-C00086.png) | 1978-10-09 |
| SE7514375L (sv) | 1976-06-28 |
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