ZA745794B - Hexahydro-dibenzo (b,d) pyran-9-ones as psychotropic or sedative drugs - Google Patents

Hexahydro-dibenzo (b,d) pyran-9-ones as psychotropic or sedative drugs

Info

Publication number
ZA745794B
ZA745794B ZA00745794A ZA745794A ZA745794B ZA 745794 B ZA745794 B ZA 745794B ZA 00745794 A ZA00745794 A ZA 00745794A ZA 745794 A ZA745794 A ZA 745794A ZA 745794 B ZA745794 B ZA 745794B
Authority
ZA
South Africa
Prior art keywords
psychotropic
dibenzo
hexahydro
pyran
ones
Prior art date
Application number
ZA00745794A
Other languages
English (en)
Inventor
R Archer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA745794B publication Critical patent/ZA745794B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
ZA00745794A 1973-11-05 1974-09-11 Hexahydro-dibenzo (b,d) pyran-9-ones as psychotropic or sedative drugs ZA745794B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US413009A US3928598A (en) 1973-11-05 1973-11-05 Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

Publications (1)

Publication Number Publication Date
ZA745794B true ZA745794B (en) 1976-04-28

Family

ID=23635412

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00745794A ZA745794B (en) 1973-11-05 1974-09-11 Hexahydro-dibenzo (b,d) pyran-9-ones as psychotropic or sedative drugs

Country Status (25)

Country Link
US (1) US3928598A (ru)
JP (1) JPS6033834B2 (ru)
AR (1) AR206409A1 (ru)
AT (1) AT337178B (ru)
BE (1) BE821719A (ru)
BG (1) BG25995A3 (ru)
CA (1) CA1029383A (ru)
CH (1) CH611290A5 (ru)
CS (1) CS193506B2 (ru)
DD (1) DD116229A5 (ru)
DE (1) DE2451932C2 (ru)
DK (1) DK136718B (ru)
ES (1) ES431675A1 (ru)
FR (1) FR2249663B1 (ru)
GB (1) GB1487636A (ru)
HU (1) HU169192B (ru)
IE (1) IE40025B1 (ru)
IL (1) IL45662A (ru)
NL (1) NL180979C (ru)
PH (1) PH10476A (ru)
PL (2) PL94965B1 (ru)
SE (1) SE415761B (ru)
SU (1) SU515457A3 (ru)
YU (1) YU36946B (ru)
ZA (1) ZA745794B (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4087546A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4102902A (en) * 1976-11-10 1978-07-25 Eli Lilly And Company Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US5498419A (en) * 1994-06-03 1996-03-12 Pars; Harry G. Fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol, 4-(diethyl-amino) butyric
US20010009965A1 (en) * 1998-05-04 2001-07-26 Alexandros Makriyannis Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6943266B1 (en) 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
AU778159B2 (en) 1999-10-18 2004-11-18 University Of Connecticut, The Peripheral cannabinoid receptor (CB2) selective ligands
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US7329651B2 (en) * 2001-01-26 2008-02-12 University Of Connecticut Cannabimimetic ligands
JP2005503998A (ja) 2001-01-29 2005-02-10 ユニバーシティ オブ コネチカット 受容体選択性のカンナビミメティックアミノアルキルインドール
EP1414775B1 (en) * 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
WO2003035005A2 (en) * 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans

Also Published As

Publication number Publication date
DE2451932C2 (de) 1983-09-29
DK136718C (ru) 1978-04-24
BG25995A3 (ru) 1979-01-12
ATA886274A (de) 1976-10-15
BE821719A (fr) 1975-04-30
IL45662A0 (en) 1974-11-29
DK573174A (ru) 1975-07-07
JPS5082073A (ru) 1975-07-03
JPS6033834B2 (ja) 1985-08-05
AU7329074A (en) 1976-03-18
YU261974A (en) 1982-06-18
AR206409A1 (es) 1976-07-23
ES431675A1 (es) 1977-04-16
IL45662A (en) 1978-03-10
GB1487636A (en) 1977-10-05
DE2451932A1 (de) 1975-05-07
CA1029383A (en) 1978-04-11
NL7414437A (nl) 1975-05-07
DK136718B (da) 1977-11-14
NL180979C (nl) 1987-06-01
SE7413832L (ru) 1975-05-06
HU169192B (ru) 1976-10-28
CS193506B2 (en) 1979-10-31
DD116229A5 (ru) 1975-11-12
PL100502B1 (pl) 1978-10-31
IE40025L (en) 1975-05-05
YU36946B (en) 1984-08-31
AT337178B (de) 1977-06-10
FR2249663B1 (ru) 1978-03-24
PL94965B1 (ru) 1977-09-30
IE40025B1 (en) 1979-02-28
US3928598A (en) 1975-12-23
SU515457A3 (ru) 1976-05-25
FR2249663A1 (ru) 1975-05-30
CH611290A5 (ru) 1979-05-31
PH10476A (en) 1977-05-11
SE415761B (sv) 1980-10-27
NL180979B (nl) 1987-01-02

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