ZA725664B - Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture - Google Patents

Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture

Info

Publication number
ZA725664B
ZA725664B ZA725664A ZA725664A ZA725664B ZA 725664 B ZA725664 B ZA 725664B ZA 725664 A ZA725664 A ZA 725664A ZA 725664 A ZA725664 A ZA 725664A ZA 725664 B ZA725664 B ZA 725664B
Authority
ZA
South Africa
Prior art keywords
iodinated
tri
methyl
manufacture
dicarboxylic acid
Prior art date
Application number
ZA725664A
Other languages
English (en)
Inventor
H Gries
H Pfeiffer
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA725664B publication Critical patent/ZA725664B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
ZA725664A 1971-08-17 1972-08-17 Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture ZA725664B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2141803A DE2141803A1 (de) 1971-08-17 1971-08-17 Trijodierte n-methyl-dicarbonsaeureani-lide und verfahren zu iher herstellung

Publications (1)

Publication Number Publication Date
ZA725664B true ZA725664B (en) 1973-05-30

Family

ID=5817319

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA725664A ZA725664B (en) 1971-08-17 1972-08-17 Tri-iodinated n-methyl-dicarboxylic acid anilides and process for their manufacture

Country Status (18)

Country Link
US (1) US4001298A (fr)
JP (1) JPS4829736A (fr)
AR (1) AR204073A1 (fr)
AT (2) AT317417B (fr)
AU (1) AU476763B2 (fr)
BE (1) BE787669A (fr)
CA (1) CA977759A (fr)
DD (1) DD100156A5 (fr)
DE (1) DE2141803A1 (fr)
DK (1) DK132375C (fr)
ES (2) ES405769A1 (fr)
FR (1) FR2150784B1 (fr)
GB (1) GB1409733A (fr)
HU (1) HU164151B (fr)
IL (1) IL40088A (fr)
NL (1) NL7209286A (fr)
SU (1) SU474974A3 (fr)
ZA (1) ZA725664B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225725A (en) * 1975-10-20 1980-09-30 Mallinckrodt, Inc. Lower alkoxymethyl esters of 2,4,6-triiodobenzoic acid derivatives
GB1539791A (en) * 1976-04-08 1979-02-07 Guerbet Sa X-ray contrast media
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
DE2629228C2 (de) * 1976-06-25 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Jodierte Isophthalamsäure-Derivate Verfahren zu deren Herstellung sowie deren Verwendung
EP0079397A1 (fr) * 1981-11-13 1983-05-25 Schering Aktiengesellschaft (2,4,6-triiodoanilides) asymétriquement substitués d'acides dicarboxyliques, leur préparation et agents de contraste pour rayons X les contenant
ATE79368T1 (de) * 1987-05-22 1992-08-15 Bracco Spa Herstellung von 5-acylamino-2,4,6-trijodo- oder tribromo-benzoesaeure-derivate.
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5869024A (en) * 1989-11-29 1999-02-09 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
US5463080A (en) * 1992-08-27 1995-10-31 Bracco International B.V. 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542861A (en) * 1967-05-08 1970-11-24 Sterling Drug Inc 3-amino-5-cycloalkylcarbonylamino-2,4,6-triiodobenzoic acids
US3732293A (en) * 1968-03-15 1973-05-08 Sterling Drug Inc Iodinated bis(aminobenzoic acids) and esters thereof

Also Published As

Publication number Publication date
AU4565072A (en) 1974-02-21
IL40088A (en) 1976-05-31
HU164151B (fr) 1973-12-28
BE787669A (fr) 1973-02-19
US4001298A (en) 1977-01-04
AU476763B2 (en) 1976-10-07
GB1409733A (en) 1975-10-15
ATA713473A (de) 1975-08-15
CA977759A (en) 1975-11-11
AT317417B (de) 1974-08-26
DK132375B (da) 1975-12-01
DD100156A5 (fr) 1973-09-12
SU474974A3 (ru) 1975-06-25
JPS4829736A (fr) 1973-04-19
DE2141803A1 (de) 1973-03-01
FR2150784A1 (fr) 1973-04-13
AR204073A1 (es) 1975-11-20
DK132375C (da) 1976-05-03
ES405769A1 (es) 1975-09-16
FR2150784B1 (fr) 1975-06-20
IL40088A0 (en) 1972-10-29
NL7209286A (fr) 1973-02-20
AT329543B (de) 1976-05-10
ES405770A1 (es) 1975-09-16

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