ZA201807617B - Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods - Google Patents

Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods

Info

Publication number
ZA201807617B
ZA201807617B ZA2018/07617A ZA201807617A ZA201807617B ZA 201807617 B ZA201807617 B ZA 201807617B ZA 2018/07617 A ZA2018/07617 A ZA 2018/07617A ZA 201807617 A ZA201807617 A ZA 201807617A ZA 201807617 B ZA201807617 B ZA 201807617B
Authority
ZA
South Africa
Prior art keywords
microorganism
related methods
ferredoxin oxidoreductase
oxidoreductase activity
modified aldehyde
Prior art date
Application number
ZA2018/07617A
Other languages
English (en)
Inventor
Liew Fungmin
Koepke Michael
Original Assignee
Lanzatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lanzatech Inc filed Critical Lanzatech Inc
Publication of ZA201807617B publication Critical patent/ZA201807617B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/07—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with an iron-sulfur protein as acceptor (1.2.7)
    • C12Y102/07005—Aldehyde ferredoxin oxidoreductase (1.2.7.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
ZA2018/07617A 2016-05-14 2018-11-13 Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods ZA201807617B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662336639P 2016-05-14 2016-05-14
PCT/US2017/032564 WO2017200884A1 (en) 2016-05-14 2017-05-12 Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods

Publications (1)

Publication Number Publication Date
ZA201807617B true ZA201807617B (en) 2021-04-28

Family

ID=60295016

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2018/07617A ZA201807617B (en) 2016-05-14 2018-11-13 Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods

Country Status (10)

Country Link
US (1) US10294498B2 (cg-RX-API-DMAC10.html)
EP (1) EP3464559A4 (cg-RX-API-DMAC10.html)
JP (2) JP7502029B2 (cg-RX-API-DMAC10.html)
KR (2) KR20230044031A (cg-RX-API-DMAC10.html)
CN (1) CN109477063A (cg-RX-API-DMAC10.html)
CA (1) CA3024114C (cg-RX-API-DMAC10.html)
EA (1) EA201892627A1 (cg-RX-API-DMAC10.html)
SG (1) SG11201810031RA (cg-RX-API-DMAC10.html)
WO (1) WO2017200884A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201807617B (cg-RX-API-DMAC10.html)

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* Cited by examiner, † Cited by third party
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KR20230044031A (ko) * 2016-05-14 2023-03-31 란자테크, 인크. 알데히드:페레독신 옥시도리덕타제 활성이 변경된 미생물 및 관련 방법
KR102073308B1 (ko) * 2017-08-29 2020-02-05 광주과학기술원 에탄올 비생산성 아세토젠 균주를 에탄올 생성균주로 전환하는 방법 및 상기 에탄올 생성균주로부터 일산화탄소를 이용한 에탄올의 제조방법
CN109929862B (zh) * 2019-03-14 2022-09-16 云南农业大学 一种从反刍动物瘤胃宏转录组数据筛选纤维素酶基因进行克隆的方法
CN121950883A (zh) * 2026-04-01 2026-05-01 中国科学院天津工业生物技术研究所 产乙醇和乙酸的产乙醇梭菌工程菌株及其构建方法和应用
CN122235036A (zh) * 2026-05-21 2026-06-19 天津大学 用于在自产乙醇梭菌中进行高效基因编辑的方法及自产乙醇梭菌工程菌株

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CN103415618A (zh) 2010-08-19 2013-11-27 新西兰郎泽科技公司 使用对含一氧化碳的底物的微生物发酵来生产化学物质的方法
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KR20230044031A (ko) * 2016-05-14 2023-03-31 란자테크, 인크. 알데히드:페레독신 옥시도리덕타제 활성이 변경된 미생물 및 관련 방법

Also Published As

Publication number Publication date
EP3464559A1 (en) 2019-04-10
EP3464559A4 (en) 2020-02-12
JP2019514441A (ja) 2019-06-06
KR102514023B1 (ko) 2023-03-23
JP7502029B2 (ja) 2024-06-18
CA3024114C (en) 2020-02-04
JP2022163046A (ja) 2022-10-25
WO2017200884A1 (en) 2017-11-23
CA3024114A1 (en) 2017-11-23
CN109477063A (zh) 2019-03-15
US10294498B2 (en) 2019-05-21
SG11201810031RA (en) 2018-12-28
US20170327849A1 (en) 2017-11-16
KR20230044031A (ko) 2023-03-31
KR20190017790A (ko) 2019-02-20
EA201892627A1 (ru) 2019-04-30

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