ZA201503467B - M. tuberculosis vaccines - Google Patents

M. tuberculosis vaccines

Info

Publication number
ZA201503467B
ZA201503467B ZA2015/03467A ZA201503467A ZA201503467B ZA 201503467 B ZA201503467 B ZA 201503467B ZA 2015/03467 A ZA2015/03467 A ZA 2015/03467A ZA 201503467 A ZA201503467 A ZA 201503467A ZA 201503467 B ZA201503467 B ZA 201503467B
Authority
ZA
South Africa
Prior art keywords
tuberculosis vaccines
tuberculosis
vaccines
Prior art date
Application number
ZA2015/03467A
Other languages
English (en)
Inventor
Andersen Peter
Thi Kim Thanh Hoang Truc
Rosenkrands Ida
Aagaard Claus
Original Assignee
Statens Seruminstitut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Seruminstitut filed Critical Statens Seruminstitut
Publication of ZA201503467B publication Critical patent/ZA201503467B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA2015/03467A 2012-10-23 2015-05-18 M. tuberculosis vaccines ZA201503467B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201200652 2012-10-23
DKPA201200653 2012-10-23
DKPA201200654 2012-10-23
DKPA201300477 2013-08-23
PCT/DK2013/000070 WO2014063704A2 (en) 2012-10-23 2013-10-18 M. tuberculosis vaccines

Publications (1)

Publication Number Publication Date
ZA201503467B true ZA201503467B (en) 2016-11-30

Family

ID=49679267

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2015/03467A ZA201503467B (en) 2012-10-23 2015-05-18 M. tuberculosis vaccines

Country Status (8)

Country Link
US (1) US9526773B2 (enExample)
EP (1) EP2912056B1 (enExample)
JP (1) JP6470179B2 (enExample)
CN (1) CN104736555B (enExample)
BR (1) BR112015009070A2 (enExample)
IN (1) IN2015DN03962A (enExample)
WO (1) WO2014063704A2 (enExample)
ZA (1) ZA201503467B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10765731B2 (en) 2014-01-09 2020-09-08 Transgene Sa Fusion of heterooligomeric mycobacterial antigens
BR112016023778A2 (pt) 2014-04-24 2017-10-17 Statens Seruminstitut proteína de fusão ou coquetel antígeno, uso de uma proteína de fusão ou coquetel antígeno, vacina, e método para a imunização de um animal, incluindo um ser humano, contra a tuberculose causada por micobactérias virulentas
KR20180061338A (ko) * 2015-09-30 2018-06-07 베링거잉겔하임베트메디카게엠베하 동물에서의 개선된 모듈러 항원 수송 분자 및 이의 용도
CN105218680B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生细胞因子的结核分支杆菌融合蛋白
CN105218681B (zh) * 2015-10-21 2019-06-25 中山大学 一种用于诱导外周血单个核细胞产生结核特异性细胞因子的融合蛋白
CN105567660B (zh) * 2016-01-08 2018-11-20 中国人民解放军第四军医大学 一种大肠杆菌重组表达结核分枝杆菌Rv2837c活性蛋白的方法及其应用
MX2018014270A (es) * 2016-05-21 2019-02-14 Infectious Disease Res Inst Composiciones y metodos para tratar la tuberculosis secundaria e infecciones po micobacteria no tuberculosa.
CN109843321A (zh) 2016-06-22 2019-06-04 国际艾滋病疫苗行动组织公司 作为结核病疫苗的重组巨细胞病毒载体
ES2950436T3 (es) 2016-12-14 2023-10-10 Becton Dickinson Co Métodos y composiciones para obtener una valoración de tuberculosis en un sujeto
IL267886B2 (en) * 2017-01-09 2024-11-01 Biomunex Pharmaceuticals A polypeptide linker for preparing multispecific antibodies
US11638749B2 (en) 2017-10-17 2023-05-02 International Aids Vaccine Initiative, Inc. Tuberculosis antigen cassettes
EP3983011A1 (en) 2019-06-14 2022-04-20 Statens Serum Institut Fusion proteins for tuberculosis vaccines
EP4007600A4 (en) * 2019-08-01 2023-08-23 Trustees of Tufts College VACCINE COMPOSITION AND METHODS OF SELECTING ANTIGENS
CN110590958B (zh) * 2019-09-11 2021-04-13 中国人民解放军总医院第八医学中心 一种串联多肽及其在抗结核分枝杆菌的免疫保护中的应用
WO2023156676A1 (en) 2022-02-21 2023-08-24 Statens Serum Institut A novel cationic adjuvant composition
CN115300618B (zh) * 2022-05-11 2026-03-27 中国农业大学 基于牛β防御素5的结核疫苗及其在预防结核病中的应用
CN115184603B (zh) * 2022-06-30 2024-02-06 首都医科大学附属北京胸科医院 EspC蛋白在制备结核分枝杆菌分离或富集产品中的应用
KR20250087737A (ko) * 2023-12-06 2025-06-17 주식회사 미코라파 결핵균에 대한 살균면역을 유도하는 융합단백질을 포함하는 결핵 백신 조성물
CN118108815B (zh) * 2024-04-23 2024-07-23 成都康华生物制品股份有限公司 结核分枝杆菌多免疫原抗原、编码其的mRNA、应用
WO2025265101A1 (en) * 2024-06-21 2025-12-26 Akagera Medicines, Inc. Lipid nanoparticles for delivery of vaccine for prevention of tuberculosis
CN119823286B (zh) * 2025-01-16 2026-02-06 中国动物卫生与流行病学中心 一种重组蛋白抗原及其在制备用于检测牛伽马干扰素试剂盒中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100797876B1 (ko) * 1998-04-07 2008-01-24 코릭사 코포레이션 마이코박테리움 튜베르쿨로시스 항원의 융합 단백질 및이의 용도
ES2346043T3 (es) * 2002-04-05 2010-10-08 Institut Pasteur Identificacion de las regiones rd1 y rd5 asociadas con la virulencia que permite el desarrollo de vacunas mejoradas de m. bovis bcg y m. microti.
KR20170072366A (ko) * 2009-04-24 2017-06-26 스태튼스 세룸 인스티튜트 재활성화를 예방하기 위한 결핵 백신
WO2012057904A1 (en) 2010-10-27 2012-05-03 Infectious Disease Research Institute Mycobacterium tuberculosis antigens and combinations thereof having high seroreactivity

Also Published As

Publication number Publication date
IN2015DN03962A (enExample) 2015-10-02
WO2014063704A2 (en) 2014-05-01
CN104736555B (zh) 2019-06-21
US20150290311A1 (en) 2015-10-15
EP2912056B1 (en) 2020-02-12
EP2912056A2 (en) 2015-09-02
JP2015536309A (ja) 2015-12-21
BR112015009070A2 (pt) 2017-07-04
CN104736555A (zh) 2015-06-24
WO2014063704A8 (en) 2015-07-30
WO2014063704A3 (en) 2014-06-19
JP6470179B2 (ja) 2019-02-13
US9526773B2 (en) 2016-12-27

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