ZA201408064B - Prodrugs of anti-platelet agents - Google Patents
Prodrugs of anti-platelet agentsInfo
- Publication number
- ZA201408064B ZA201408064B ZA2014/08064A ZA201408064A ZA201408064B ZA 201408064 B ZA201408064 B ZA 201408064B ZA 2014/08064 A ZA2014/08064 A ZA 2014/08064A ZA 201408064 A ZA201408064 A ZA 201408064A ZA 201408064 B ZA201408064 B ZA 201408064B
- Authority
- ZA
- South Africa
- Prior art keywords
- prodrugs
- platelet agents
- platelet
- agents
- Prior art date
Links
- 229940127218 antiplatelet drug Drugs 0.000 title 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1781CH2012 | 2012-05-07 | ||
| PCT/IB2013/052328 WO2013168024A1 (en) | 2012-05-07 | 2013-03-24 | Prodrugs of anti-platelet agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201408064B true ZA201408064B (en) | 2016-04-28 |
Family
ID=54193687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2014/08064A ZA201408064B (en) | 2012-05-07 | 2014-11-04 | Prodrugs of anti-platelet agents |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2847197A4 (https=) |
| JP (1) | JP2015519334A (https=) |
| CN (1) | CN104379589A (https=) |
| AU (1) | AU2013257745A1 (https=) |
| CA (1) | CA2873094A1 (https=) |
| SG (1) | SG11201407307YA (https=) |
| WO (1) | WO2013168024A1 (https=) |
| ZA (1) | ZA201408064B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201407328TA (en) * | 2012-07-03 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of moderate to severe pain |
| CN119033782B (zh) * | 2020-07-29 | 2025-04-25 | 上海柯君医药科技有限公司 | 抗血小板药物和其用途 |
| CN114507157B (zh) * | 2020-11-17 | 2023-03-24 | 沧州维智达美制药有限公司 | 一种利用氯乙腈制备溴乙腈的方法 |
| CN119019320B (zh) * | 2024-10-29 | 2025-03-11 | 上海柯君医药科技有限公司 | 一种具有抗血小板活性的哌啶类化合物的制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858734B2 (en) * | 2003-04-23 | 2005-02-22 | Rhodia Pharma Solutions Inc. | Preparation of (S)-Clopidogrel and related compounds |
| CN101123878A (zh) * | 2003-07-29 | 2008-02-13 | 信号研发控股有限责任公司 | 氨基酸前药 |
| EP1889835A4 (en) * | 2005-05-27 | 2010-04-28 | Daiichi Sankyo Co Ltd | CYCLIC AMINE DERIVATIVE WITH SUBSTITUTED ALKYL GROUP |
| KR100990949B1 (ko) * | 2008-06-09 | 2010-10-29 | 엔자이텍 주식회사 | 클로피도그렐 및 그의 유도체의 제조방법 |
| CN102002053A (zh) * | 2009-09-02 | 2011-04-06 | 陕西合成药业有限公司 | 用于治疗的四氢噻吩并吡啶衍生物 |
| CN102336767A (zh) * | 2011-07-11 | 2012-02-01 | 华东理工大学 | 制备高纯度手性α-取代-6,7-二氢噻吩并[3,2-c]吡啶衍生物的方法 |
| WO2013024376A1 (en) * | 2011-08-16 | 2013-02-21 | Mahesh Kandula | Compositions and methods for the treatment of atherothrombosis |
| US9525998B2 (en) * | 2012-01-06 | 2016-12-20 | Qualcomm Incorporated | Wireless display with multiscreen service |
| JP6097766B2 (ja) * | 2012-01-27 | 2017-03-15 | インターデイジタル パテント ホールディングス インコーポレイテッド | マルチキャリアベースおよび/または疑似照合ネットワークにおいてepdcchを提供するためのシステムおよび/または方法 |
| WO2013167985A1 (en) * | 2012-05-07 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of neurological disorders |
| SG11201407317SA (en) * | 2012-05-08 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for suppression of carbonic anhydrase activity |
| WO2013167987A1 (en) * | 2012-05-08 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of diabetes |
| JP2015526385A (ja) * | 2012-05-08 | 2015-09-10 | セリックスビオ プライヴェート リミテッド | てんかんの治療のための組成物及び方法 |
| CA2872976A1 (en) * | 2012-05-08 | 2013-11-14 | Cellixbio Private Limited | Compositions and methods for the treatment of neurological disorders |
| SG11201407328TA (en) * | 2012-07-03 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of moderate to severe pain |
-
2013
- 2013-03-24 CN CN201380030644.9A patent/CN104379589A/zh active Pending
- 2013-03-24 SG SG11201407307YA patent/SG11201407307YA/en unknown
- 2013-03-24 AU AU2013257745A patent/AU2013257745A1/en not_active Abandoned
- 2013-03-24 CA CA2873094A patent/CA2873094A1/en not_active Abandoned
- 2013-03-24 EP EP13787471.5A patent/EP2847197A4/en not_active Withdrawn
- 2013-03-24 WO PCT/IB2013/052328 patent/WO2013168024A1/en not_active Ceased
- 2013-03-24 JP JP2015510901A patent/JP2015519334A/ja active Pending
-
2014
- 2014-11-04 ZA ZA2014/08064A patent/ZA201408064B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201407307YA (en) | 2014-12-30 |
| AU2013257745A1 (en) | 2014-11-27 |
| JP2015519334A (ja) | 2015-07-09 |
| WO2013168024A1 (en) | 2013-11-14 |
| EP2847197A1 (en) | 2015-03-18 |
| CA2873094A1 (en) | 2013-11-14 |
| CN104379589A (zh) | 2015-02-25 |
| EP2847197A4 (en) | 2015-11-04 |
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