ZA201408064B - Prodrugs of anti-platelet agents - Google Patents

Prodrugs of anti-platelet agents

Info

Publication number
ZA201408064B
ZA201408064B ZA2014/08064A ZA201408064A ZA201408064B ZA 201408064 B ZA201408064 B ZA 201408064B ZA 2014/08064 A ZA2014/08064 A ZA 2014/08064A ZA 201408064 A ZA201408064 A ZA 201408064A ZA 201408064 B ZA201408064 B ZA 201408064B
Authority
ZA
South Africa
Prior art keywords
prodrugs
platelet agents
platelet
agents
Prior art date
Application number
ZA2014/08064A
Other languages
English (en)
Inventor
Mahesh Kandula
Original Assignee
Cellix Bio Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellix Bio Private Ltd filed Critical Cellix Bio Private Ltd
Publication of ZA201408064B publication Critical patent/ZA201408064B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2014/08064A 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents ZA201408064B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1781CH2012 2012-05-07
PCT/IB2013/052328 WO2013168024A1 (en) 2012-05-07 2013-03-24 Prodrugs of anti-platelet agents

Publications (1)

Publication Number Publication Date
ZA201408064B true ZA201408064B (en) 2016-04-28

Family

ID=54193687

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/08064A ZA201408064B (en) 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents

Country Status (8)

Country Link
EP (1) EP2847197A4 (cg-RX-API-DMAC10.html)
JP (1) JP2015519334A (cg-RX-API-DMAC10.html)
CN (1) CN104379589A (cg-RX-API-DMAC10.html)
AU (1) AU2013257745A1 (cg-RX-API-DMAC10.html)
CA (1) CA2873094A1 (cg-RX-API-DMAC10.html)
SG (1) SG11201407307YA (cg-RX-API-DMAC10.html)
WO (1) WO2013168024A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201408064B (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013285126A1 (en) * 2012-07-03 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of moderate to severe pain
CN119552111B (zh) * 2020-07-29 2026-01-02 上海柯君医药科技有限公司 抗血小板药物和其用途
CN114507157B (zh) * 2020-11-17 2023-03-24 沧州维智达美制药有限公司 一种利用氯乙腈制备溴乙腈的方法
CN119019320B (zh) * 2024-10-29 2025-03-11 上海柯君医药科技有限公司 一种具有抗血小板活性的哌啶类化合物的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858734B2 (en) * 2003-04-23 2005-02-22 Rhodia Pharma Solutions Inc. Preparation of (S)-Clopidogrel and related compounds
JP2007510621A (ja) * 2003-07-29 2007-04-26 シグニチャー アールアンドディー ホールディングス，エルエルシー． アミノ酸プロドラッグ
TW200720252A (en) * 2005-05-27 2007-06-01 Sankyo Co Cyclic amine derivative having substituted alkyl group
KR100990949B1 (ko) * 2008-06-09 2010-10-29 엔자이텍 주식회사 클로피도그렐 및 그의 유도체의 제조방법
CN102002053A (zh) * 2009-09-02 2011-04-06 陕西合成药业有限公司 用于治疗的四氢噻吩并吡啶衍生物
CN102336767A (zh) * 2011-07-11 2012-02-01 华东理工大学 制备高纯度手性α-取代-6,7-二氢噻吩并[3,2-c]吡啶衍生物的方法
WO2013024376A1 (en) * 2011-08-16 2013-02-21 Mahesh Kandula Compositions and methods for the treatment of atherothrombosis
US9525998B2 (en) * 2012-01-06 2016-12-20 Qualcomm Incorporated Wireless display with multiscreen service
CN107257275B (zh) * 2012-01-27 2021-03-16 交互数字专利控股公司 由WTRU执行的用于ePDCCH的方法、WTRU、搜索空间监视方法和UE
US9738631B2 (en) * 2012-05-07 2017-08-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
EP2846795A2 (en) * 2012-05-08 2015-03-18 Cellixbio Private Limited Compositions and methods for the treatment of epilepsy
SG11201407317SA (en) * 2012-05-08 2014-12-30 Cellix Bio Private Ltd Compositions and methods for suppression of carbonic anhydrase activity
WO2013167987A1 (en) * 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of diabetes
AU2013257710B2 (en) * 2012-05-08 2016-10-20 Cellixbio Private Limited Compositions and methods for the treatment of neurological disorders
AU2013285126A1 (en) * 2012-07-03 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of moderate to severe pain

Also Published As

Publication number Publication date
CA2873094A1 (en) 2013-11-14
EP2847197A4 (en) 2015-11-04
WO2013168024A1 (en) 2013-11-14
AU2013257745A1 (en) 2014-11-27
EP2847197A1 (en) 2015-03-18
CN104379589A (zh) 2015-02-25
JP2015519334A (ja) 2015-07-09
SG11201407307YA (en) 2014-12-30

Similar Documents

Publication Publication Date Title
IL277912B (en) Intentional healing
IL236456A0 (en) targeted treatments
ZA201501847B (en) Formulations of enzalutamide
GB201116864D0 (en) Requirements characterisation
PL2819982T3 (pl) Proleki witaminy k
ZA201406082B (en) Use of ccr3-inhibitors
GB201513279D0 (en) Micro-evolution of microbes
GB201222832D0 (en) Manufacture of hollow parts
PL2922628T3 (pl) Mieszanka odtłuszczająca
PL2888228T3 (pl) Inhibitory oddziaływania CD40-TRAF6
GB201211019D0 (en) Inhibitor compounds
ZA201502350B (en) Solid form of hihydro-pyrido-oxazine derivative
ZA201307229B (en) Prodrugs of d-isoglutamyl-[d/l]- tryprophan
ZA201307230B (en) Prodrugs of d-gamma-glutamyl-d-tryptophan and d-gamma-glutamyl-l-tryptophan
GB201204590D0 (en) Prodrugs of thiazolamine compounds
GB201207606D0 (en) Prodrugs
GB201115380D0 (en) Prodrugs of methotrexate and related compounds and uses thereof
GB201204587D0 (en) Prodrugs of guanidine compounds
GB201204589D0 (en) Prodrugs of guanidine compounds
GB201110636D0 (en) Prodrugs
IL231452A0 (en) Amorphous form of dolutegravir
EP2826490A4 (en) BIOFILM INHIBITORS
GB201209895D0 (en) Use of a composition
GB201115652D0 (en) Water stable form of glutamine
HUE036665T2 (hu) Dihidro-pirido-oxazin származék szilárd formái