ZA201105441B - Ethanamine compounds and their use for treating depression - Google Patents

Ethanamine compounds and their use for treating depression

Info

Publication number
ZA201105441B
ZA201105441B ZA2011/05441A ZA201105441A ZA201105441B ZA 201105441 B ZA201105441 B ZA 201105441B ZA 2011/05441 A ZA2011/05441 A ZA 2011/05441A ZA 201105441 A ZA201105441 A ZA 201105441A ZA 201105441 B ZA201105441 B ZA 201105441B
Authority
ZA
South Africa
Prior art keywords
treating depression
ethanamine
compounds
ethanamine compounds
depression
Prior art date
Application number
ZA2011/05441A
Other languages
English (en)
Inventor
Michael Balestra
Glen E Ernst
John P Mccauley
Lihong Shen
Peter Bernstein
William Frietze
David Nugiel
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42288011&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201105441(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA201105441B publication Critical patent/ZA201105441B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Confectionery (AREA)
ZA2011/05441A 2008-12-24 2011-07-22 Ethanamine compounds and their use for treating depression ZA201105441B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14067308P 2008-12-24 2008-12-24
PCT/SE2009/051493 WO2010074647A1 (en) 2008-12-24 2009-12-22 Ethanamine compounds and their use for treating depression

Publications (1)

Publication Number Publication Date
ZA201105441B true ZA201105441B (en) 2012-03-28

Family

ID=42288011

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/05441A ZA201105441B (en) 2008-12-24 2011-07-22 Ethanamine compounds and their use for treating depression

Country Status (31)

Country Link
US (4) US8013165B2 (OSRAM)
EP (2) EP2391606A4 (OSRAM)
JP (1) JP5491524B2 (OSRAM)
KR (1) KR20110097996A (OSRAM)
CN (1) CN102333762B (OSRAM)
AR (1) AR074981A1 (OSRAM)
AU (1) AU2009330745B2 (OSRAM)
BR (1) BRPI0923476A2 (OSRAM)
CA (1) CA2748235A1 (OSRAM)
CL (1) CL2011001590A1 (OSRAM)
CO (1) CO6450688A2 (OSRAM)
CR (1) CR20110365A (OSRAM)
CU (1) CU24017B1 (OSRAM)
DO (1) DOP2011000205A (OSRAM)
EA (1) EA201190064A1 (OSRAM)
EC (1) ECSP11011161A (OSRAM)
GT (1) GT201100186A (OSRAM)
HN (1) HN2011001773A (OSRAM)
IL (1) IL213518A0 (OSRAM)
MX (1) MX2011006680A (OSRAM)
NI (1) NI201100131A (OSRAM)
NZ (1) NZ593282A (OSRAM)
PE (1) PE20120249A1 (OSRAM)
SA (1) SA109310013B1 (OSRAM)
SG (2) SG171928A1 (OSRAM)
SV (1) SV2011003962A (OSRAM)
TW (1) TWI442922B (OSRAM)
UA (1) UA106056C2 (OSRAM)
UY (1) UY32360A (OSRAM)
WO (1) WO2010074647A1 (OSRAM)
ZA (1) ZA201105441B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2391606A4 (en) * 2008-12-24 2012-06-13 Astrazeneca Ab ETHANAMINE COMPOUNDS AND THEIR APPLICATION FOR THE TREATMENT OF DEPRESSION
CN112250676B (zh) * 2020-11-24 2023-05-16 深圳市第二人民医院(深圳市转化医学研究院) 一种具有抗抑郁活性的含氧杂环化合物
CN112279843B (zh) * 2020-11-24 2023-05-16 深圳市第二人民医院(深圳市转化医学研究院) 一种具有抗抑郁活性的含氮杂环化合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422191A (en) * 1965-01-21 1969-01-14 Synergistics Inc Compositions and methods for tranquilization employing salts of n-morpholine ethanol
GB1427026A (en) 1972-11-20 1976-03-03 Ici Ltd Synthetic film materials
JPS5756474B2 (OSRAM) 1973-05-26 1982-11-30
GB9320273D0 (en) 1993-04-01 1993-11-17 Fisons Corp Compound useful in therapy
US5455259A (en) * 1987-02-06 1995-10-03 Fisons Corporation Compounds for the treatment of neurodegenerative disorders
SG52662A1 (en) 1988-08-12 1998-09-28 Astra Ab Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties
JP2514855B2 (ja) 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 光学活性なアラニンアニリド誘導体の酸付加塩
US5206248A (en) * 1992-03-27 1993-04-27 Smith Richard A Method for reducing emotional lability
ATE188212T1 (de) * 1991-10-30 2000-01-15 Astra Ab 2-pyrazinylethylamin-derivate und ihre verwendung als arzneimittel.
UA29437C2 (uk) 1992-04-03 2000-11-15 Астра АБ (s)-альфа-феніл-2-піридинетанамін або його сіль з неорганічною кислотою, які мають протисудомну активність, спосіб їх отримання, лікарський препарат на їх основі та спосіб лікування судом
NZ332334A (en) * 1996-04-19 2000-06-23 Akzo Nobel Nv Substituted benzylamines and their use for the treatment of depression and other neurologically related disorders
DE69809827D1 (de) 1997-03-31 2003-01-16 Korea Res Inst Chem Tech Chinolinische Sulfid-Derivate als NMDA Rezeptor-Antagonisten und Verfahren zu ihrer Herstellung
TW544448B (en) 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
SE9901077D0 (sv) * 1999-03-23 1999-03-23 Astra Ab Novel use
SE9901340D0 (sv) * 1999-04-15 1999-04-15 Astra Pharma Prod Novel process
DE10334188B4 (de) * 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
EP2391606A4 (en) 2008-12-24 2012-06-13 Astrazeneca Ab ETHANAMINE COMPOUNDS AND THEIR APPLICATION FOR THE TREATMENT OF DEPRESSION

Also Published As

Publication number Publication date
NI201100131A (es) 2012-03-19
US9035065B2 (en) 2015-05-19
CL2011001590A1 (es) 2012-06-22
SA109310013B1 (ar) 2013-07-28
NZ593282A (en) 2013-06-28
JP2012513993A (ja) 2012-06-21
US20120277272A1 (en) 2012-11-01
BRPI0923476A2 (pt) 2016-01-19
CO6450688A2 (es) 2012-05-31
CU20110141A7 (es) 2012-01-31
CN102333762A (zh) 2012-01-25
DOP2011000205A (es) 2011-07-15
AR074981A1 (es) 2011-03-02
AU2009330745B2 (en) 2012-04-05
IL213518A0 (en) 2011-07-31
CU24017B1 (es) 2014-07-30
TW201028149A (en) 2010-08-01
HN2011001773A (es) 2014-08-18
SV2011003962A (es) 2012-01-06
KR20110097996A (ko) 2011-08-31
WO2010074647A1 (en) 2010-07-01
PE20120249A1 (es) 2012-04-19
SG192510A1 (en) 2013-08-30
UA106056C2 (uk) 2014-07-25
MX2011006680A (es) 2011-07-12
US8013165B2 (en) 2011-09-06
CN102333762B (zh) 2014-06-11
UY32360A (es) 2010-07-30
EA201190064A1 (ru) 2012-02-28
AU2009330745A1 (en) 2011-08-04
ECSP11011161A (es) 2011-07-29
EP2391606A4 (en) 2012-06-13
EP2391606A1 (en) 2011-12-07
JP5491524B2 (ja) 2014-05-14
SG171928A1 (en) 2011-07-28
EP2610246A1 (en) 2013-07-03
US20130137731A1 (en) 2013-05-30
US20100179199A1 (en) 2010-07-15
US20120115913A1 (en) 2012-05-10
CR20110365A (es) 2011-08-09
TWI442922B (zh) 2014-07-01
GT201100186A (es) 2013-10-08
CA2748235A1 (en) 2010-07-01

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