ZA201104310B - Pyrrolidines - Google Patents

Pyrrolidines

Info

Publication number
ZA201104310B
ZA201104310B ZA2011/04310A ZA201104310A ZA201104310B ZA 201104310 B ZA201104310 B ZA 201104310B ZA 2011/04310 A ZA2011/04310 A ZA 2011/04310A ZA 201104310 A ZA201104310 A ZA 201104310A ZA 201104310 B ZA201104310 B ZA 201104310B
Authority
ZA
South Africa
Prior art keywords
pyrrolidines
Prior art date
Application number
ZA2011/04310A
Other languages
English (en)
Inventor
Kevin Neil Dack
Sarah Elizabeth Skerratt
James Edward John Mills
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of ZA201104310B publication Critical patent/ZA201104310B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2011/04310A 2008-11-10 2011-06-09 Pyrrolidines ZA201104310B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11286908P 2008-11-10 2008-11-10
PCT/IB2009/054824 WO2010052625A1 (en) 2008-11-10 2009-10-30 Pyrrolidines

Publications (1)

Publication Number Publication Date
ZA201104310B true ZA201104310B (en) 2012-02-29

Family

ID=41503565

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/04310A ZA201104310B (en) 2008-11-10 2011-06-09 Pyrrolidines

Country Status (31)

Country Link
US (1) US8278343B2 (enExample)
EP (1) EP2364296A1 (enExample)
JP (1) JP2012508225A (enExample)
KR (1) KR20110083733A (enExample)
CN (1) CN102209710A (enExample)
AP (1) AP2011005728A0 (enExample)
AR (1) AR074314A1 (enExample)
AU (1) AU2009312427B2 (enExample)
BR (1) BRPI0920924A2 (enExample)
CA (1) CA2741589A1 (enExample)
CL (1) CL2011001034A1 (enExample)
CO (1) CO6382112A2 (enExample)
CR (1) CR20110217A (enExample)
CU (1) CU20110093A7 (enExample)
DO (1) DOP2011000127A (enExample)
EA (1) EA201100549A1 (enExample)
EC (1) ECSP11011032A (enExample)
GE (1) GEP20125607B (enExample)
IL (1) IL212490A0 (enExample)
MA (1) MA32782B1 (enExample)
MX (1) MX2011004903A (enExample)
NI (1) NI201100092A (enExample)
NZ (1) NZ592311A (enExample)
PA (1) PA8848001A1 (enExample)
PE (1) PE20110663A1 (enExample)
SV (1) SV2011003896A (enExample)
TN (1) TN2011000211A1 (enExample)
TW (1) TW201022234A (enExample)
UY (1) UY32228A (enExample)
WO (1) WO2010052625A1 (enExample)
ZA (1) ZA201104310B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR074776A1 (es) * 2008-12-18 2011-02-09 Sanofi Aventis Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente
TW201326154A (zh) 2011-11-28 2013-07-01 拜耳知識產權公司 作為ep2受體拮抗劑之新穎2h-吲唑
JPWO2013176220A1 (ja) * 2012-05-25 2016-01-14 国立大学法人京都大学 概日リズム調整
CN110041269A (zh) * 2019-05-16 2019-07-23 海门瑞一医药科技有限公司 一种2-氯-5-羟基嘧啶的制备方法
WO2022272062A1 (en) 2021-06-24 2022-12-29 Reservoir Neuroscience, Inc. Ep2 antagonist compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157355T1 (de) * 1991-01-21 1997-09-15 Shionogi & Co 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga
US7335680B2 (en) * 2001-12-20 2008-02-26 Laboratoires Serono Sa Pyrrolidine derivatives as prostaglandin modulators
WO2007005176A1 (en) * 2005-06-29 2007-01-11 Allergan, Inc. Pyrrolidinones for the treatment of glaucoma and ocular hypertension
US7592364B2 (en) * 2006-02-28 2009-09-22 Allergan, Inc. Substituted gamma lactams as therapeutic agents
US7550448B2 (en) * 2006-05-24 2009-06-23 Allergan, Inc. Therapeutic compounds
DE102006039912A1 (de) * 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
BRPI0811444A2 (pt) * 2007-05-10 2014-10-29 Pfizer Ltd Derivados de azetidina e seu uso como antagonistas da prostaglandina e2.

Also Published As

Publication number Publication date
CN102209710A (zh) 2011-10-05
US8278343B2 (en) 2012-10-02
TW201022234A (en) 2010-06-16
CR20110217A (es) 2011-05-12
AU2009312427B2 (en) 2011-10-20
UY32228A (es) 2010-06-30
SV2011003896A (es) 2011-07-05
TN2011000211A1 (fr) 2012-12-17
AP2011005728A0 (en) 2011-06-30
CO6382112A2 (es) 2012-02-15
NI201100092A (es) 2011-10-31
CL2011001034A1 (es) 2011-11-11
KR20110083733A (ko) 2011-07-20
US20100120793A1 (en) 2010-05-13
MX2011004903A (es) 2011-05-30
WO2010052625A1 (en) 2010-05-14
PA8848001A1 (es) 2010-06-28
BRPI0920924A2 (pt) 2016-10-04
CA2741589A1 (en) 2010-05-14
AU2009312427A1 (en) 2010-05-14
MA32782B1 (fr) 2011-11-01
ECSP11011032A (es) 2011-06-30
EP2364296A1 (en) 2011-09-14
DOP2011000127A (es) 2011-07-15
IL212490A0 (en) 2011-06-30
AR074314A1 (es) 2011-01-05
JP2012508225A (ja) 2012-04-05
CU20110093A7 (es) 2012-01-31
PE20110663A1 (es) 2011-09-23
GEP20125607B (en) 2012-08-10
EA201100549A1 (ru) 2011-12-30
NZ592311A (en) 2012-12-21

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