ZA201001015B - (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament - Google Patents

(Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament

Info

Publication number
ZA201001015B
ZA201001015B ZA201001015A ZA201001015A ZA201001015B ZA 201001015 B ZA201001015 B ZA 201001015B ZA 201001015 A ZA201001015 A ZA 201001015A ZA 201001015 A ZA201001015 A ZA 201001015A ZA 201001015 B ZA201001015 B ZA 201001015B
Authority
ZA
South Africa
Prior art keywords
phenyl
carboxylalkylene
oxalamides
medicament
production
Prior art date
Application number
ZA201001015A
Other languages
English (en)
Inventor
Elisabeth Defossa
Viktoria Dietrich
Guido Haschke
Johanna Kuhlmann
Thomas Klabunde
Siegfried Stengelin
Andreas Herling
Stefan Bartoschek
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of ZA201001015B publication Critical patent/ZA201001015B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/80—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA201001015A 2007-09-21 2010-02-11 (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament ZA201001015B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07291132 2007-09-21

Publications (1)

Publication Number Publication Date
ZA201001015B true ZA201001015B (en) 2010-10-27

Family

ID=39111451

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201001015A ZA201001015B (en) 2007-09-21 2010-02-11 (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament

Country Status (20)

Country Link
US (2) US8518875B2 (fr)
EP (1) EP2203416B1 (fr)
JP (1) JP5427784B2 (fr)
KR (1) KR20100061692A (fr)
CN (1) CN101796017A (fr)
AR (1) AR068479A1 (fr)
AU (1) AU2008303976B9 (fr)
CA (1) CA2700028A1 (fr)
CL (1) CL2008002742A1 (fr)
CO (1) CO6260062A2 (fr)
IL (1) IL204555A0 (fr)
MA (1) MA31710B1 (fr)
MX (1) MX2010002461A (fr)
MY (1) MY149648A (fr)
NZ (1) NZ584049A (fr)
RU (1) RU2488578C2 (fr)
TW (1) TWI439265B (fr)
UY (1) UY31350A1 (fr)
WO (1) WO2009039943A1 (fr)
ZA (1) ZA201001015B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201290574A1 (ru) 2009-12-25 2012-12-28 Мотида Фармасьютикал Ко., Лтд. Новое производное 3-гидрокси-5-арилизотиазола
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
EP2612669A4 (fr) 2010-08-31 2014-05-14 Snu R&Db Foundation Utilisation de la reprogrammation f tale d'un agoniste des ppar
CA2813639A1 (fr) 2010-10-08 2012-04-12 Mochida Pharmaceutical Co. Ltd. Derive d'amide cyclique
NZ617409A (en) 2011-04-27 2015-08-28 Mochida Pharm Co Ltd Novel 3-hydroxyisothiazole 1-oxide derivative
CA2834465A1 (fr) 2011-04-28 2012-11-01 Mochida Pharmaceutical Co., Ltd. Derive d'amide cyclique
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr) 2011-09-27 2015-10-21 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
EP2800736A1 (fr) * 2012-01-04 2014-11-12 Sanofi Acides 3-[4-(phénylamino oxalyl amino) phényl]hex-4-énoïques, leur procédé de préparation et leur utilisation comme médicament
IN2015DN03795A (fr) 2012-10-24 2015-10-02 Inserm Inst Nat De La Santé Et De La Rech Médicale
JPWO2015046317A1 (ja) * 2013-09-30 2017-03-09 国立大学法人 岡山大学 新規アセチレンアミド誘導体
EP3076959B1 (fr) 2013-12-04 2018-07-04 Merck Sharp & Dohme Corp. Composés bicycliques antidiabétiques
WO2015119899A1 (fr) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Composés antidiabétiques
EP3273981B1 (fr) 2015-03-24 2020-04-29 INSERM - Institut National de la Santé et de la Recherche Médicale Procédé et composition pharmaceutique pour une utilisation dans le traitement du diabète
WO2019160882A1 (fr) 2018-02-13 2019-08-22 Gilead Sciences, Inc. Inhibiteurs pd -1/pd-l1
US10899735B2 (en) 2018-04-19 2021-01-26 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
JP7105359B2 (ja) 2018-07-13 2022-07-22 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
US11236085B2 (en) 2018-10-24 2022-02-01 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
AU2020363377A1 (en) 2019-10-07 2022-04-21 Kallyope, Inc. GPR119 agonists
CN114728917B (zh) * 2019-12-04 2023-12-08 深圳信立泰药业股份有限公司 草酰胺类衍生物、其制备方法及其在医药上的应用
EP4153589A4 (fr) 2020-05-19 2024-06-12 Kallyope, Inc. Activateurs d'ampk
WO2021263039A1 (fr) 2020-06-26 2021-12-30 Kallyope, Inc. Activateurs d'ampk

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1618196B1 (de) * 1966-02-07 1971-12-09 Ciba Geigy Verwendung von asymmetrischen Oxalsäure-diarylamiden als Ultraviolettschutzmittel
FR2727114B1 (fr) * 1994-11-17 1996-12-27 Oreal Nouveaux filtres solaires, compositions cosmetiques photoprotectrices les contenant et utilisations
US6803357B1 (en) * 1998-02-02 2004-10-12 New England Medical Center Hospitals, Inc. Method of regulating glucose metabolism, and reagents related thereto
US6890568B2 (en) * 1999-05-24 2005-05-10 Grant Pierce Method for management of blood glucose levels
US6867299B2 (en) * 2000-02-24 2005-03-15 Hoffmann-La Roche Inc. Oxamide IMPDH inhibitors
HU227197B1 (en) 2000-10-24 2010-10-28 Richter Gedeon Nyrt Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them
WO2002096876A1 (fr) * 2001-05-25 2002-12-05 Boehringer Ingelheim Pharmaceuticals, Inc. Composes de carbamate et d'oxamide inhibant la production de cytokine
ITRM20020016A1 (it) * 2002-01-15 2003-07-15 Sigma Tau Ind Farmaceuti Derivati di acidi fenil(alchil)carbossilici e derivati fenilalchileterociclici dionici, loro uso come medicamenti ad attivita' ipoglicemizza
JP4224979B2 (ja) * 2002-04-09 2009-02-18 大正製薬株式会社 インターロイキン１２抑制剤
CA2744893A1 (fr) * 2002-06-27 2004-01-08 Novo Nordisk A/S Derives d'arylcarbonyle servant d'activateurs de glucokinase
US20050124667A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Oxamide inhibitors of plasminogen activator inhibitor-1

Also Published As

Publication number Publication date
MY149648A (en) 2013-09-30
JP2010539199A (ja) 2010-12-16
TWI439265B (zh) 2014-06-01
EP2203416A1 (fr) 2010-07-07
US20100261645A1 (en) 2010-10-14
NZ584049A (en) 2011-05-27
UY31350A1 (es) 2009-04-30
CO6260062A2 (es) 2011-03-22
AU2008303976B2 (en) 2013-04-18
EP2203416B1 (fr) 2016-10-26
CL2008002742A1 (es) 2009-01-16
US20130231388A1 (en) 2013-09-05
AU2008303976B9 (en) 2013-09-12
AU2008303976A1 (en) 2009-04-02
CN101796017A (zh) 2010-08-04
IL204555A0 (en) 2010-11-30
KR20100061692A (ko) 2010-06-08
AR068479A1 (es) 2009-11-18
CA2700028A1 (fr) 2009-04-02
TW200927088A (en) 2009-07-01
RU2010115748A (ru) 2011-10-27
WO2009039943A1 (fr) 2009-04-02
JP5427784B2 (ja) 2014-02-26
MX2010002461A (es) 2010-03-26
US8518875B2 (en) 2013-08-27
MA31710B1 (fr) 2010-09-01
RU2488578C2 (ru) 2013-07-27

Similar Documents

Publication Publication Date Title
ZA201001015B (en) (Carboxylalkylene-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament
IL204556A0 (en) (cyclopropyl-phenyl)-phenyl-oxalamides, method for the production thereof, and use of same as a medicament
ZA200908428B (en) Method for the production of a component, and component
ZA200805939B (en) Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
IL219530A (en) Converted 4-aminocyclohexane compounds, drugs containing these compounds and their use in the preparation of drugs
EP2151500A4 (fr) -glucan ramifié, -glucosyltransférase produisant celui-ci, son procédé de fabrication et son utilisation
IL195245A0 (en) Substituted prolinamides, production thereof and their use as drugs
EP2130909A4 (fr) Procédé de production de dent et dent produite par le procédé
IL181012A0 (en) Substituted 8-aminoalkoxi-xanthines, method for the production thereof and use thereof as medicaments
HRP20130558T1 (hr) Derivat 17-hidroksi-17-pentafluoretil-estra-4,9(10)-dien-11-arila, postupci za njegovu proizvodnju i njegova uporaba za lijeäśenje bolesti
IL193341A0 (en) Novel azacyclyl-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
IL193339A0 (en) Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
EP2412706A4 (fr) Nouveau dérivé hydroxamate, procédé de production associé, et composition pharmaceutique comprenant le dérivé
EP2025672A4 (fr) Anneau hétérocycliques à 7 éléments, son procédé de production et ses utilisations pharmaceutiques
EP2199446A4 (fr) Matière de fibres alumineuses, son procédé de production et utilisation
EP2141229A4 (fr) Préparation pulvérulente de lipase, procédé de fabrication de celle-ci et son utilisation
PL2346493T3 (pl) Tabletki wielocząstkowe i sposób ich wytwarzania
ZA201000520B (en) Substituted tetrahydronaphthalenes, process for the preparation thereof and the use thereof as medicaments
EP2123662A4 (fr) Composé tréhalose, procédé de fabrication du composé et agent immunostimulant comprenant le composé
HK1149011A1 (en) Triazolopyridazines as par1 inhibitors, production thereof, and use for producing medicaments
EP2330212A4 (fr) Nouveau composé céramidastine, son procédé de fabrication et son utilisation
EP2327789A4 (fr) Nouveau composé de signamycine, procédé pour la production de celui-ci, et utilisation de celui-ci
PL1999112T3 (pl) Podstawione 2-amino-4-fenylo-dihydrochinoliny, sposób ich wytwarzania, ich zastosowanie jako leku i lek je zawierający
PT2190913E (pt) Processo para a produção de formulações aquosas, formulações aquosas e a sua utilização
EP2039681A4 (fr) Dérives de cycloalkène, procédé de production des dérivés et utilisation de ceux-ci