ZA201000238B - Process and intermediate for the production of a tertiary alcohol as an intermediate in the synthesis of montelukast - Google Patents

Process and intermediate for the production of a tertiary alcohol as an intermediate in the synthesis of montelukast

Info

Publication number
ZA201000238B
ZA201000238B ZA201000238A ZA201000238A ZA201000238B ZA 201000238 B ZA201000238 B ZA 201000238B ZA 201000238 A ZA201000238 A ZA 201000238A ZA 201000238 A ZA201000238 A ZA 201000238A ZA 201000238 B ZA201000238 B ZA 201000238B
Authority
ZA
South Africa
Prior art keywords
montelukast
production
tertiary alcohol
synthesis
reacting
Prior art date
Application number
ZA201000238A
Other languages
English (en)
Inventor
John Mcgarrity
Francis Djojo
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of ZA201000238B publication Critical patent/ZA201000238B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA201000238A 2007-07-13 2010-01-12 Process and intermediate for the production of a tertiary alcohol as an intermediate in the synthesis of montelukast ZA201000238B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07013810A EP2014650A1 (en) 2007-07-13 2007-07-13 Process and intermediate for the production of an intermediate in the production of montelukast

Publications (1)

Publication Number Publication Date
ZA201000238B true ZA201000238B (en) 2010-09-29

Family

ID=38786992

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201000238A ZA201000238B (en) 2007-07-13 2010-01-12 Process and intermediate for the production of a tertiary alcohol as an intermediate in the synthesis of montelukast

Country Status (13)

Country Link
US (1) US20100190987A1 (xx)
EP (2) EP2014650A1 (xx)
JP (1) JP2010533207A (xx)
KR (1) KR20100044844A (xx)
CN (1) CN101808997A (xx)
AT (1) ATE531694T1 (xx)
AU (1) AU2008277938A1 (xx)
BR (1) BRPI0814526A2 (xx)
CA (1) CA2692896A1 (xx)
EA (1) EA201000099A1 (xx)
TW (1) TW200914425A (xx)
WO (1) WO2009010230A2 (xx)
ZA (1) ZA201000238B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116332220B (zh) * 2023-05-29 2023-08-11 研峰科技(北京)有限公司 一种氯化镧(iii)双(氯化锂)的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266568A (en) * 1990-10-12 1993-11-30 Merck Frosst Canada, Inc. Hydroxyalkylquinoline ether acids as leukotriene antagonists
AR057908A1 (es) * 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar montelukast e intermediarios del mismo

Also Published As

Publication number Publication date
EP2178841A2 (en) 2010-04-28
EP2178841B1 (en) 2011-11-02
ATE531694T1 (de) 2011-11-15
AU2008277938A1 (en) 2009-01-22
TW200914425A (en) 2009-04-01
US20100190987A1 (en) 2010-07-29
WO2009010230A2 (en) 2009-01-22
WO2009010230A3 (en) 2009-04-23
KR20100044844A (ko) 2010-04-30
EA201000099A1 (ru) 2010-06-30
CA2692896A1 (en) 2009-01-22
BRPI0814526A2 (pt) 2015-01-27
CN101808997A (zh) 2010-08-18
JP2010533207A (ja) 2010-10-21
EP2014650A1 (en) 2009-01-14

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