ZA200904159B - Bisulfite purification of an alpha-keto amide - Google Patents

Bisulfite purification of an alpha-keto amide

Info

Publication number
ZA200904159B
ZA200904159B ZA200904159A ZA200904159A ZA200904159B ZA 200904159 B ZA200904159 B ZA 200904159B ZA 200904159 A ZA200904159 A ZA 200904159A ZA 200904159 A ZA200904159 A ZA 200904159A ZA 200904159 B ZA200904159 B ZA 200904159B
Authority
ZA
South Africa
Prior art keywords
alpha
keto amide
bisulfite
purification
bisulfite purification
Prior art date
Application number
ZA200904159A
Other languages
English (en)
Inventor
George S K Wong
Jeonghan Park
Tetsuo Iwama
Anantha R Sudhakar
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA200904159B publication Critical patent/ZA200904159B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200904159A 2006-12-15 2009-06-12 Bisulfite purification of an alpha-keto amide ZA200904159B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87519506P 2006-12-15 2006-12-15

Publications (1)

Publication Number Publication Date
ZA200904159B true ZA200904159B (en) 2010-03-31

Family

ID=39434141

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904159A ZA200904159B (en) 2006-12-15 2009-06-12 Bisulfite purification of an alpha-keto amide

Country Status (9)

Country Link
US (1) US8222427B2 (xx)
EP (1) EP2121604A2 (xx)
JP (1) JP5220026B2 (xx)
CN (1) CN101610999A (xx)
AR (1) AR064357A1 (xx)
CA (1) CA2672268A1 (xx)
MX (1) MX2009006477A (xx)
WO (1) WO2008076316A2 (xx)
ZA (1) ZA200904159B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015004685A2 (en) 2013-07-12 2015-01-15 Mylan Laboratories Ltd An improved process for the purification of boceprevir
CN103804445B (zh) * 2013-12-30 2016-01-13 广州自远生物科技有限公司 一种改进的乙酰异戊酰泰乐菌素的制备方法
RU2554514C1 (ru) * 2014-04-24 2015-06-27 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский Томский государственный университет" Способ получения натриевой соли глиоксалевой кислоты из продуктов окисления глиоксаля
CN110563670B (zh) * 2019-08-27 2021-09-28 河北威远生物化工有限公司 一种含硫哌嗪衍生物及其应用
CN111269121B (zh) * 2020-03-10 2023-04-07 广州巨元生化有限公司 一种8-氧代-3,7-二甲基-2,6-辛二烯基羧酸酯化合物的纯化方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1385870T1 (sl) * 2000-07-21 2010-08-31 Schering Corp Peptidi kot NS3-serin proteazni inhibitorji virusa hepatitisa C
AU2001289583A1 (en) 2000-09-15 2002-03-26 Lid Systems A/S A closure system for closing a container
US7332600B2 (en) * 2001-11-16 2008-02-19 Ranbaxy Laboratories Limited Process for the preparation of crystalline imipenem
AR044694A1 (es) * 2003-06-17 2005-09-21 Schering Corp Proceso y compuestos intermedios para la preparacion de (1r, 2s,5s) - 3 azabiciclo [3,1,0] hexano-2- carboxamida, n- [3- amino-1- (ciclobutilmetil) - 2, 3 - dioxopropil] -3- [ (2s) - 2 - [[ [ 1,1- dimetiletil] amino] carbonilamino] -3,3-dimetil -1- oxobutil]-6,6 dimetilo
PE20060309A1 (es) 2004-05-06 2006-04-13 Schering Corp (1r,2s,5s)-n-[(1s)-3-amino-1-(ciclobutilmetil)-2,3-dioxopropil]-3-[(2s)-2[[[(1,1-dimetiletil)amino]carbonil]amino]-3,3-dimetil-1-oxobutil]-6,6-dimetil-3-azabiciclo[3.1.o]hexan-2-carboxamida como inhibidor de la ns3/ns4a serina proteasa del virus de l
ES2374379T3 (es) * 2005-01-14 2012-02-16 Schering Corporation Síntesis exo y diastereoselectiva de análogos de himbacina.
DE602006013492D1 (de) * 2005-08-19 2010-05-20 Vertex Pharma Verfahren und zwischenprodukte

Also Published As

Publication number Publication date
US8222427B2 (en) 2012-07-17
CA2672268A1 (en) 2008-06-26
JP2010513281A (ja) 2010-04-30
CN101610999A (zh) 2009-12-23
MX2009006477A (es) 2009-06-26
US20090326244A1 (en) 2009-12-31
JP5220026B2 (ja) 2013-06-26
AR064357A1 (es) 2009-04-01
WO2008076316A3 (en) 2008-10-09
WO2008076316A2 (en) 2008-06-26
EP2121604A2 (en) 2009-11-25

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