ZA200903953B - High protein concentration formulations containing mannitol - Google Patents
High protein concentration formulations containing mannitolInfo
- Publication number
- ZA200903953B ZA200903953B ZA200903953A ZA200903953A ZA200903953B ZA 200903953 B ZA200903953 B ZA 200903953B ZA 200903953 A ZA200903953 A ZA 200903953A ZA 200903953 A ZA200903953 A ZA 200903953A ZA 200903953 B ZA200903953 B ZA 200903953B
- Authority
- ZA
- South Africa
- Prior art keywords
- protein concentration
- formulations containing
- high protein
- containing mannitol
- concentration formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87352606P | 2006-12-06 | 2006-12-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200903953B true ZA200903953B (en) | 2010-03-31 |
Family
ID=39493053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200903953A ZA200903953B (en) | 2006-12-06 | 2009-06-05 | High protein concentration formulations containing mannitol |
Country Status (13)
Country | Link |
---|---|
US (1) | US20080139792A1 (fr) |
EP (1) | EP2089001A2 (fr) |
JP (1) | JP2010512336A (fr) |
KR (1) | KR20090086632A (fr) |
CN (1) | CN101631535A (fr) |
AU (1) | AU2007329333A1 (fr) |
BR (1) | BRPI0720125A2 (fr) |
CA (1) | CA2671571A1 (fr) |
IL (1) | IL198977A0 (fr) |
MX (1) | MX2009005984A (fr) |
RU (1) | RU2009120200A (fr) |
WO (1) | WO2008070721A2 (fr) |
ZA (1) | ZA200903953B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2009010361A (es) | 2007-03-29 | 2009-10-16 | Abbott Lab | Anticuerpos il-12 anti-humanos cristalinos. |
US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
CN101969971A (zh) * | 2007-11-30 | 2011-02-09 | 雅培制药有限公司 | 蛋白制剂及其制备方法 |
EP2288338A1 (fr) | 2008-05-15 | 2011-03-02 | Baxter International Inc. | Formulations pharmaceutiques stables |
KR20110096553A (ko) * | 2008-11-28 | 2011-08-30 | 아보트 러보러터리즈 | 안정한 항체 조성물 및 이의 안정화 방법 |
US9265834B2 (en) | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
WO2010100135A1 (fr) | 2009-03-05 | 2010-09-10 | Ablynx N.V. | Nouveaux complexes dimères de liaison antigénique, méthodes d'obtention/non obtention et leurs utilisations |
RU2560701C2 (ru) * | 2009-05-04 | 2015-08-20 | Эббви Байотекнолоджи Лтд. | Стабильные композиции с высокими концентрациями белков антител человека против tnf-альфа |
EP2473528B1 (fr) | 2009-09-03 | 2014-12-03 | Ablynx N.V. | Formulations stables de polypeptides et leurs utilisations |
WO2016202713A1 (fr) * | 2015-06-15 | 2016-12-22 | F. Hoffmann-La Roche Ag | Procédé de congélation de solutions protéiques |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA902663B (en) * | 1989-04-07 | 1991-12-24 | Syntex Inc | Interleukin-1 formulation |
US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
JP4317010B2 (ja) * | 2001-07-25 | 2009-08-19 | ピーディーエル バイオファーマ,インコーポレイティド | IgG抗体の安定な凍結乾燥医薬製剤 |
US20040191243A1 (en) * | 2002-12-13 | 2004-09-30 | Bei Chen | System and method for stabilizing antibodies with histidine |
WO2006014965A2 (fr) * | 2004-07-27 | 2006-02-09 | Human Genome Sciences, Inc. | Preparation pharmaceutique et processus |
-
2007
- 2007-12-05 WO PCT/US2007/086507 patent/WO2008070721A2/fr active Application Filing
- 2007-12-05 AU AU2007329333A patent/AU2007329333A1/en not_active Abandoned
- 2007-12-05 US US11/950,986 patent/US20080139792A1/en not_active Abandoned
- 2007-12-05 MX MX2009005984A patent/MX2009005984A/es not_active Application Discontinuation
- 2007-12-05 EP EP07868997A patent/EP2089001A2/fr not_active Withdrawn
- 2007-12-05 RU RU2009120200/15A patent/RU2009120200A/ru not_active Application Discontinuation
- 2007-12-05 JP JP2009540450A patent/JP2010512336A/ja not_active Withdrawn
- 2007-12-05 CN CN200780045479A patent/CN101631535A/zh active Pending
- 2007-12-05 KR KR1020097013969A patent/KR20090086632A/ko not_active Application Discontinuation
- 2007-12-05 CA CA002671571A patent/CA2671571A1/fr not_active Abandoned
- 2007-12-05 BR BRPI0720125-7A patent/BRPI0720125A2/pt not_active Application Discontinuation
-
2009
- 2009-05-26 IL IL198977A patent/IL198977A0/en unknown
- 2009-06-05 ZA ZA200903953A patent/ZA200903953B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010512336A (ja) | 2010-04-22 |
RU2009120200A (ru) | 2011-01-20 |
US20080139792A1 (en) | 2008-06-12 |
EP2089001A2 (fr) | 2009-08-19 |
WO2008070721A2 (fr) | 2008-06-12 |
IL198977A0 (en) | 2010-02-17 |
CA2671571A1 (fr) | 2008-06-12 |
KR20090086632A (ko) | 2009-08-13 |
AU2007329333A1 (en) | 2008-06-12 |
BRPI0720125A2 (pt) | 2014-01-28 |
MX2009005984A (es) | 2009-06-16 |
CN101631535A (zh) | 2010-01-20 |
WO2008070721A3 (fr) | 2008-09-18 |
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