ZA200901248B - Stabilized therapeutic small helical antiviral peptides - Google Patents

Stabilized therapeutic small helical antiviral peptides

Info

Publication number
ZA200901248B
ZA200901248B ZA200901248A ZA200901248A ZA200901248B ZA 200901248 B ZA200901248 B ZA 200901248B ZA 200901248 A ZA200901248 A ZA 200901248A ZA 200901248 A ZA200901248 A ZA 200901248A ZA 200901248 B ZA200901248 B ZA 200901248B
Authority
ZA
South Africa
Prior art keywords
small helical
antiviral peptides
therapeutic small
stabilized therapeutic
stabilized
Prior art date
Application number
ZA200901248A
Other languages
English (en)
Inventor
Asim Kumar Debnath
Hongtao Zhang
Qian Zhao
Original Assignee
New York Blood Ct Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Ct Inc filed Critical New York Blood Ct Inc
Publication of ZA200901248B publication Critical patent/ZA200901248B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200901248A 2006-10-05 2009-02-20 Stabilized therapeutic small helical antiviral peptides ZA200901248B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84955106P 2006-10-05 2006-10-05

Publications (1)

Publication Number Publication Date
ZA200901248B true ZA200901248B (en) 2010-04-28

Family

ID=39283347

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200901248A ZA200901248B (en) 2006-10-05 2009-02-20 Stabilized therapeutic small helical antiviral peptides

Country Status (8)

Country Link
US (1) US8940864B2 (cg-RX-API-DMAC7.html)
EP (2) EP2073829B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010505831A (cg-RX-API-DMAC7.html)
AU (1) AU2007307254A1 (cg-RX-API-DMAC7.html)
CA (1) CA2665186A1 (cg-RX-API-DMAC7.html)
ES (1) ES2387827T3 (cg-RX-API-DMAC7.html)
WO (1) WO2008045238A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200901248B (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
KR20160061439A (ko) 2007-03-28 2016-05-31 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
JP2011522796A (ja) * 2008-05-06 2011-08-04 ニューヨーク ブラッド センター, インコーポレイテッド 抗ウイルス細胞透過性ペプチド
BRPI0918833A2 (pt) * 2008-09-22 2015-12-08 Aileron Therapeutics Inc macrociclos peptidomiméticos
BRPI1006139A2 (pt) 2009-01-14 2017-05-30 Aileron Therapeutics Inc macrociclos peptidomiméticos
MX355543B (es) 2010-08-13 2018-04-20 Aileron Therapeutics Inc Star Macrociclos peptidomiméticos.
RU2639523C2 (ru) 2011-10-18 2017-12-21 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы и их применение
JP6450191B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス,インコーポレイテッド ペプチドミメティック大環状化合物
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
US9604919B2 (en) 2012-11-01 2017-03-28 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
SG11201702223UA (en) 2014-09-24 2017-04-27 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
WO2016049355A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
US10308684B2 (en) 2014-11-28 2019-06-04 Seoul National University R&Db Foundation Cell penetrating stapled peptide, manufacturing method therefor, and use thereof
EP3294318A4 (en) 2015-03-20 2019-04-03 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2017018595A1 (ko) * 2015-07-28 2017-02-02 동국대학교 산학협력단 이중 스테이플화된 펩타이드 및 이의 용도
JP2018528217A (ja) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. Mcl−1のモジュレーターとしてのペプチド模倣大環状分子
WO2019133179A2 (en) * 2017-12-01 2019-07-04 Massachusetts Institute Of Technology Solution-phase affinity selection of inhibitors from combinatorial peptide libraries
US20200102356A1 (en) * 2018-10-01 2020-04-02 NMC Inc. Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants
WO2022036049A2 (en) * 2020-08-12 2022-02-17 New York Blood Center, Inc. Antiviral stapled peptides against sars-cov-2

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187548B1 (en) * 1993-05-23 2001-02-13 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods using human calcium sensor protein, fragments thereof and DNA encoding same
US6239270B1 (en) * 1993-05-24 2001-05-29 Rhone-Poulenc Rorer S.A. Nucleic acids encoding human calcium sensor protein
US6790950B2 (en) * 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
JP4892134B2 (ja) * 1999-04-09 2012-03-07 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌ワクチン組成物
US7192713B1 (en) * 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
US20020124273A1 (en) * 2000-10-17 2002-09-05 Jean-Marc Roch Protein-protein interactions in neurodegenerative diseases
CA2830063C (en) * 2003-11-05 2017-10-31 Dana-Farber Cancer Institute, Inc. Stabilized alpha helical peptides and uses thereof
US20100159477A1 (en) * 2006-07-13 2010-06-24 Peter Hornbeck Reagents for the detection of protein phosphorylation in signaling pathways
WO2008008998A2 (en) * 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
EP2061487A4 (en) * 2006-09-11 2009-12-02 Univ Illinois MODIFIED CUPREDOXIN-DERIVED PEPTIDES AND METHOD FOR THEIR USE
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
JP5078401B2 (ja) * 2007-03-27 2012-11-21 株式会社Adeka 防水シート
WO2009042237A2 (en) * 2007-09-26 2009-04-02 Dana Farber Cancer Institute Methods and compositions for modulating bcl-2 family polypeptides
CA2713089C (en) * 2008-01-23 2017-11-21 Dana Farber Cancer Institute Compositions and methods for the treatment of viral infections
JP2011522796A (ja) * 2008-05-06 2011-08-04 ニューヨーク ブラッド センター, インコーポレイテッド 抗ウイルス細胞透過性ペプチド
US20110218155A1 (en) * 2008-10-10 2011-09-08 Dana-Farber Cancer Institute, Inc. Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides

Also Published As

Publication number Publication date
CA2665186A1 (en) 2008-04-17
EP2517720A1 (en) 2012-10-31
EP2073829A2 (en) 2009-07-01
ES2387827T3 (es) 2012-10-02
WO2008045238A3 (en) 2008-07-24
US20100130430A1 (en) 2010-05-27
US8940864B2 (en) 2015-01-27
WO2008045238A2 (en) 2008-04-17
JP2010505831A (ja) 2010-02-25
AU2007307254A1 (en) 2008-04-17
EP2073829A4 (en) 2010-03-03
EP2073829B1 (en) 2012-06-20

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