ZA200807302B - Polymorphs of N-(4-chloro-3-methyl-5-isoxazolyl)2-[-2-methyl-4,5-(methylenedioxy) phenylacetyl]thiophene-3-sulfonamide, sodium salt - Google Patents

Polymorphs of N-(4-chloro-3-methyl-5-isoxazolyl)2-[-2-methyl-4,5-(methylenedioxy) phenylacetyl]thiophene-3-sulfonamide, sodium salt

Info

Publication number
ZA200807302B
ZA200807302B ZA200807302A ZA200807302A ZA200807302B ZA 200807302 B ZA200807302 B ZA 200807302B ZA 200807302 A ZA200807302 A ZA 200807302A ZA 200807302 A ZA200807302 A ZA 200807302A ZA 200807302 B ZA200807302 B ZA 200807302B
Authority
ZA
South Africa
Prior art keywords
methyl
phenylacetyl
methylenedioxy
polymorphs
isoxazolyl
Prior art date
Application number
ZA200807302A
Other languages
English (en)
Inventor
John F Reichwein
Hansen Tim
Original Assignee
Encysive Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encysive Pharmaceuticals Inc filed Critical Encysive Pharmaceuticals Inc
Publication of ZA200807302B publication Critical patent/ZA200807302B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200807302A 2006-03-13 2008-08-25 Polymorphs of N-(4-chloro-3-methyl-5-isoxazolyl)2-[-2-methyl-4,5-(methylenedioxy) phenylacetyl]thiophene-3-sulfonamide, sodium salt ZA200807302B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78186106P 2006-03-13 2006-03-13

Publications (1)

Publication Number Publication Date
ZA200807302B true ZA200807302B (en) 2009-11-25

Family

ID=38335653

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807302A ZA200807302B (en) 2006-03-13 2008-08-25 Polymorphs of N-(4-chloro-3-methyl-5-isoxazolyl)2-[-2-methyl-4,5-(methylenedioxy) phenylacetyl]thiophene-3-sulfonamide, sodium salt

Country Status (14)

Country Link
US (1) US20090104265A1 (enExample)
EP (1) EP1996582A2 (enExample)
JP (1) JP2009530279A (enExample)
KR (1) KR101019264B1 (enExample)
CN (1) CN101443329A (enExample)
AU (1) AU2007225206B2 (enExample)
BR (1) BRPI0709384A2 (enExample)
CA (1) CA2644134A1 (enExample)
IL (1) IL193682A0 (enExample)
MX (1) MX2008011843A (enExample)
NZ (1) NZ570943A (enExample)
RU (1) RU2412941C2 (enExample)
WO (1) WO2007106467A2 (enExample)
ZA (1) ZA200807302B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008112241A1 (en) * 2007-03-13 2008-09-18 Encysive Pharmaceuticals, Inc. Methods an compositions for treatment of an interstitial lung disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5793705A (en) * 1996-09-18 1998-08-11 International Business Machines Corporation Ultrasonic liquid level gauge for tanks subject to movement and vibration
US5783705A (en) * 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
JP4097893B2 (ja) * 2000-12-05 2008-06-11 株式会社エフ・ティ・エスコーポレーション 対向ターゲット式スパッタ方法及び導電性膜の形成方法
ES2274234T3 (es) * 2002-03-15 2007-05-16 Novartis Ag 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3(4-piridin-3-il)pirimidin -2-ilamino)fenil)-benzamida para el tratamiento de enfermedades mediadas por ang ii.
GB0223854D0 (en) * 2002-10-12 2002-11-20 Astrazeneca Ab Therapeutic treatment
US20060205733A1 (en) * 2004-08-26 2006-09-14 Encysive Pharmaceuticals Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof

Also Published As

Publication number Publication date
BRPI0709384A2 (pt) 2011-03-22
IL193682A0 (en) 2009-05-04
WO2007106467A3 (en) 2007-10-25
NZ570943A (en) 2010-09-30
MX2008011843A (es) 2008-10-02
CA2644134A1 (en) 2007-09-20
WO2007106467A2 (en) 2007-09-20
AU2007225206A1 (en) 2007-09-20
EP1996582A2 (en) 2008-12-03
KR101019264B1 (ko) 2011-03-07
KR20080106926A (ko) 2008-12-09
AU2007225206B2 (en) 2010-08-05
CN101443329A (zh) 2009-05-27
RU2412941C2 (ru) 2011-02-27
US20090104265A1 (en) 2009-04-23
RU2008136316A (ru) 2010-04-20
JP2009530279A (ja) 2009-08-27

Similar Documents

Publication Publication Date Title
IL196527A0 (en) Substituted heteroaryl derivatives
DK1813614T3 (da) Cytotoksiske midler, der omfatter nye tomaymycinderivater
ZA200709087B (en) Novel thiophene derivatives as sphingosine-1-phosphate-1 receptor agonists
ZA200802488B (en) 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors
DOP2007000084A (es) Derivados de dihidropirazolopirimidinona
BRPI0918045A2 (pt) compostos de carboxamida heterocíclicos
IL198524A0 (en) Substituted heteroaryl pyridopyrimidone derivatives
ZA200900670B (en) Heteroaryl compounds useful as inhititors of E1 activating enzymes
IL195158A0 (en) Novel heterocyclic compounds
CR10562A (es) Nuevos derivados de piridazina
IL190608A0 (en) 5-(arylsulfonyl)-pyrazolopiperidines
IL195669A0 (en) Novel heteroaryl substituted benzoxazoles
IL201189A0 (en) Fluorinated derivatives of deferiprone
IL198005A0 (en) Ccr2 antagonists for treatment of fibrosis
CR10809A (es) Derivados de heteroaril-pirrolidinil-y-piperidinil-cetona
SI2176229T1 (sl) Nove kristalne oblike 3-(difluormetil)-1-metil-n-(3',4',5'-trifluor(1,1'-bifenil)-2-il)-1h- pirazol-4-karboksamida
CR10759A (es) Farmaco combinado
GB0622472D0 (en) Novel heterocyclic derivatives
IL194389A0 (en) Process for preparing heterocyclic derivatives
GB2448834B (en) Preparation of salts of escitalopram
IL189928A0 (en) Thiophene derivatives for the treatment of diabetes
EP1976841A4 (en) HETEROCYCLIC AMIDDERIVES AS CALCIUM CHANNEL BLOCKERS
ZA200807302B (en) Polymorphs of N-(4-chloro-3-methyl-5-isoxazolyl)2-[-2-methyl-4,5-(methylenedioxy) phenylacetyl]thiophene-3-sulfonamide, sodium salt
EP2512489A4 (en) FORMULATIONS FROM ACADESIN
EP2057144A4 (en) NEW POLYMORPHIC FROM RIMONABANT