ZA200804294B - Materials and methods for treating chronic fibrotic disease - Google Patents

Materials and methods for treating chronic fibrotic disease

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Publication number
ZA200804294B
ZA200804294B ZA200804294A ZA200804294A ZA200804294B ZA 200804294 B ZA200804294 B ZA 200804294B ZA 200804294 A ZA200804294 A ZA 200804294A ZA 200804294 A ZA200804294 A ZA 200804294A ZA 200804294 B ZA200804294 B ZA 200804294B
Authority
ZA
South Africa
Prior art keywords
materials
methods
treating chronic
fibrotic disease
chronic fibrotic
Prior art date
Application number
ZA200804294A
Other languages
English (en)
Inventor
Cory M Hogaboam
Steven L Kunkel
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Publication of ZA200804294B publication Critical patent/ZA200804294B/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
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    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/12—Antihypertensives
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/207—Modifications characterised by siRNA, miRNA
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
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ZA200804294A 2005-12-23 2006-12-19 Materials and methods for treating chronic fibrotic disease ZA200804294B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75364705P 2005-12-23 2005-12-23

Publications (1)

Publication Number Publication Date
ZA200804294B true ZA200804294B (en) 2009-07-29

Family

ID=38218516

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200804294A ZA200804294B (en) 2005-12-23 2006-12-19 Materials and methods for treating chronic fibrotic disease

Country Status (16)

Country Link
US (1) US8795668B2 (pt)
EP (1) EP1963492A4 (pt)
JP (1) JP2009528977A (pt)
KR (1) KR20080081069A (pt)
CN (1) CN101351545A (pt)
BR (1) BRPI0619638A2 (pt)
CA (1) CA2633641A1 (pt)
MA (1) MA31060B1 (pt)
MX (1) MX2008008238A (pt)
NO (1) NO20082434L (pt)
NZ (1) NZ568991A (pt)
RU (1) RU2446825C2 (pt)
TN (1) TNSN08277A1 (pt)
TW (1) TW200733974A (pt)
WO (1) WO2007075592A2 (pt)
ZA (1) ZA200804294B (pt)

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JP5337405B2 (ja) 2007-09-17 2013-11-06 ザ・ホスピタル・フォー・シック・チルドレン ゴーシェ病の治療方法
WO2009121031A1 (en) * 2008-03-27 2009-10-01 Vascular Biosciences, Inc. Methods of novel therapeutic candidate identification through gene expression analysis in vascular-related diseases
WO2010062640A1 (en) * 2008-10-28 2010-06-03 Gilead Colorado, Inc. Methods for treating idiopathic pulmonary fibrosis and associated complications
JP5801202B2 (ja) * 2009-09-29 2015-10-28 学校法人慶應義塾 抗腫瘍剤およびそのスクリーニング方法
WO2011047287A1 (en) * 2009-10-15 2011-04-21 Immuneregen Biosciences, Inc. Methods of treating inflammatory and fibrotic lung diseases with substance p analogs
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EP2623592B1 (en) 2010-09-28 2019-05-15 NB Health Laboratory Co. Ltd. Anti-human ccr7 antibodies, hybridoma, medicinal composition, and antibody-immobilized carrier
KR101697396B1 (ko) * 2011-02-02 2017-01-17 엑스칼리아드 파마슈티컬즈, 인코포레이티드 결합 조직 성장 인자（ctgf）를 표적으로 하는 안티센스 화합물을 사용하여 켈로이드 또는 비후성 흉터를 치료하는 방법
GB201118840D0 (en) * 2011-11-01 2011-12-14 Univ Sheffield Pulmonary hypertension II
CN102526114A (zh) * 2011-12-27 2012-07-04 苏州人本药业有限公司 物理改性后的眼镜蛇蛇毒在制备治疗肺纤维化药物中的用途
WO2015147335A1 (ja) * 2014-03-27 2015-10-01 国立大学法人大阪大学 脳マラリアの診断および治療
US20170035703A1 (en) * 2015-10-29 2017-02-09 Hans M. Albertsen Method of Treating Adhesion by Altering an Epithelial to Mesenchymal Transition
EP3604529A4 (en) * 2017-03-29 2021-01-06 Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences MICRO-RNA AND USES THEREOF IN THE PREVENTION AND TREATMENT OF MEDICAL SIGNS AND / OR SYNDROME OF FIBROPLASIA
WO2018195392A1 (en) * 2017-04-20 2018-10-25 Thomas Jefferson University Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion and pulmonary fibrosis formation
EP3724219A4 (en) * 2017-12-14 2021-09-08 The University of Chicago TREATMENT OF FIBROSIS BY GENETICALLY MODIFIED MACROPHAGES
CN108524912A (zh) * 2018-04-26 2018-09-14 高常青 一种肺纤维化动物模型的构建方法
RU2735054C1 (ru) * 2020-02-27 2020-10-27 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации Способ профилактики развития реперфузионного поражения ткани легкого с помощью неинвазивной искусственной вентиляции лёгких постоянным положительным давлением у неоперабельных больных с хронической тромбоэмболической легочной гипертензией после транслюминальной баллонной ангиопластики легочной артерии

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Publication number Publication date
WO2007075592A3 (en) 2008-06-12
RU2008130410A (ru) 2010-01-27
US8795668B2 (en) 2014-08-05
MX2008008238A (es) 2009-01-07
CN101351545A (zh) 2009-01-21
US20070172856A1 (en) 2007-07-26
WO2007075592A9 (en) 2007-09-13
TNSN08277A1 (en) 2009-10-30
WO2007075592A2 (en) 2007-07-05
EP1963492A4 (en) 2010-06-09
NO20082434L (no) 2008-08-26
MA31060B1 (fr) 2010-01-04
KR20080081069A (ko) 2008-09-05
RU2446825C2 (ru) 2012-04-10
JP2009528977A (ja) 2009-08-13
BRPI0619638A2 (pt) 2011-10-04
EP1963492A2 (en) 2008-09-03
NZ568991A (en) 2012-04-27
TW200733974A (en) 2007-09-16
CA2633641A1 (en) 2007-07-05

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