ZA200802854B - Method to predict or monitor the response of a patient to an ErbB receptor drug - Google Patents
Method to predict or monitor the response of a patient to an ErbB receptor drugInfo
- Publication number
- ZA200802854B ZA200802854B ZA200802854A ZA200802854A ZA200802854B ZA 200802854 B ZA200802854 B ZA 200802854B ZA 200802854 A ZA200802854 A ZA 200802854A ZA 200802854 A ZA200802854 A ZA 200802854A ZA 200802854 B ZA200802854 B ZA 200802854B
- Authority
- ZA
- South Africa
- Prior art keywords
- predict
- patient
- monitor
- response
- erbb receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2005003823 | 2005-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200802854B true ZA200802854B (en) | 2009-06-24 |
Family
ID=36114238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200802854A ZA200802854B (en) | 2005-10-05 | 2005-10-20 | Method to predict or monitor the response of a patient to an ErbB receptor drug |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20080286785A1 (zh) |
| EP (1) | EP1931798A1 (zh) |
| JP (1) | JP2009511008A (zh) |
| KR (1) | KR20080028857A (zh) |
| CN (1) | CN101351563A (zh) |
| AU (1) | AU2005337051A1 (zh) |
| BR (1) | BRPI0520530A2 (zh) |
| CA (1) | CA2624613A1 (zh) |
| IL (1) | IL189705A0 (zh) |
| NO (1) | NO20081198L (zh) |
| NZ (1) | NZ566387A (zh) |
| TW (1) | TW200714716A (zh) |
| WO (1) | WO2007039705A1 (zh) |
| ZA (1) | ZA200802854B (zh) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101155579B (zh) | 2005-02-03 | 2012-10-31 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
| CN103110948A (zh) | 2005-11-04 | 2013-05-22 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| WO2008100624A2 (en) | 2007-02-16 | 2008-08-21 | Merrimack Pharmaceuticals, Inc. | Antibodies against erbb3 and uses thereof |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| KR20130088908A (ko) | 2008-06-17 | 2013-08-08 | 와이어쓰 엘엘씨 | Ｈｋｉ-272 및 비노렐빈을 함유하는 항신생물성 조합물 |
| CN109464445A (zh) | 2008-08-04 | 2019-03-15 | 惠氏有限责任公司 | 4-苯胺基-3-氰基喹啉和卡培他滨的抗肿瘤组合 |
| UA104868C2 (uk) | 2008-08-15 | 2014-03-25 | Меррімак Фармасьютікалз, Інк. | Спосіб лікування пацієнта, що має неопластичну пухлину, відповідно до спрогнозованої реакції |
| ES2941894T3 (es) | 2009-04-06 | 2023-05-26 | Wyeth Llc | Régimen de tratamiento que utiliza neratinib contra el cáncer de mama |
| RU2636614C2 (ru) * | 2009-05-19 | 2017-11-24 | Вивия Байотек С.Л. | Способы персонализированного медицинского тестирования ex vivo на гематологические новообразования |
| US20120316187A1 (en) | 2009-11-13 | 2012-12-13 | Pangaea Biotech, S.L. | Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer |
| CN102812045B (zh) * | 2009-11-13 | 2018-04-13 | 第一三共欧洲有限公司 | 用于治疗或预防人表皮生长因子受体‑3(her‑3)相关疾病的材料和方法 |
| DK2544680T3 (en) | 2010-03-11 | 2015-04-27 | Merrimack Pharmaceuticals Inc | USE OF ErbB3 INHIBITORS IN TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER |
| EP3219814B1 (en) * | 2010-10-29 | 2023-02-15 | ARKRAY, Inc. | Probe for detection of polymorphism in egfr gene, amplification primer, and use thereof |
| WO2012065071A2 (en) * | 2010-11-12 | 2012-05-18 | The Broad Institute Of Mit And Harvard | Methods of predicting response to egfr antibody therapy |
| EP2468883A1 (en) | 2010-12-22 | 2012-06-27 | Pangaea Biotech S.L. | Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer |
| EP2492688A1 (en) | 2011-02-23 | 2012-08-29 | Pangaea Biotech, S.A. | Molecular biomarkers for predicting response to antitumor treatment in lung cancer |
| CN107419018B (zh) * | 2012-02-16 | 2020-09-04 | 江苏宏微特斯医药科技有限公司 | 一种基于Blocker引物和ARMS引物检测基因突变的方法和试剂盒 |
| WO2013190089A1 (en) | 2012-06-21 | 2013-12-27 | Pangaea Biotech, S.L. | Molecular biomarkers for predicting outcome in lung cancer |
| ES2662598T3 (es) * | 2013-03-08 | 2018-04-09 | F. Hoffmann-La Roche Ag | Análisis de sangre para la detección de mutaciones de EGFR |
| WO2015100459A2 (en) | 2013-12-27 | 2015-07-02 | Merrimack Pharmaceuticals, Inc. | Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies |
| CN106795567B (zh) * | 2014-10-09 | 2021-07-30 | 豪夫迈·罗氏有限公司 | 在表皮生长因子受体激酶结构域中的突变 |
| GB201507202D0 (en) | 2015-04-28 | 2015-06-10 | Stfc Science & Technology | Receptor tyosine kinase biomarkers |
| US10184006B2 (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors |
| WO2018129645A1 (en) * | 2017-01-10 | 2018-07-19 | Wang, Wei | Lasofoxifene modulation of membrane-initiated estrogen signals and methods for tumor treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9403953D0 (sv) * | 1994-07-15 | 1994-11-16 | Pharmacia Biotech Ab | Sequence-based diagnosis |
| US6759217B2 (en) * | 1996-03-26 | 2004-07-06 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| GB9812768D0 (en) * | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US20070275386A1 (en) * | 2004-03-01 | 2007-11-29 | Ratain Mark J | Polymorphisms in the Epidermal Growth Factor Receptor Gene Promoter |
| EP1733056B1 (en) * | 2004-03-31 | 2013-05-22 | The General Hospital Corporation | Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments |
| WO2005118876A2 (en) * | 2004-06-04 | 2005-12-15 | Genentech, Inc. | Egfr mutations |
| GB2424886A (en) * | 2005-04-04 | 2006-10-11 | Dxs Ltd | Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations |
| US20060223178A1 (en) * | 2005-04-05 | 2006-10-05 | Tom Barber | Devices and methods for magnetic enrichment of cells and other particles |
-
2005
- 2005-10-20 EP EP05803602A patent/EP1931798A1/en not_active Withdrawn
- 2005-10-20 ZA ZA200802854A patent/ZA200802854B/xx unknown
- 2005-10-20 CA CA002624613A patent/CA2624613A1/en not_active Abandoned
- 2005-10-20 CN CNA2005800517835A patent/CN101351563A/zh active Pending
- 2005-10-20 NZ NZ566387A patent/NZ566387A/en not_active IP Right Cessation
- 2005-10-20 BR BRPI0520530-1A patent/BRPI0520530A2/pt not_active IP Right Cessation
- 2005-10-20 AU AU2005337051A patent/AU2005337051A1/en not_active Abandoned
- 2005-10-20 WO PCT/GB2005/004036 patent/WO2007039705A1/en active Application Filing
- 2005-10-20 JP JP2008534061A patent/JP2009511008A/ja active Pending
- 2005-10-20 KR KR1020087005875A patent/KR20080028857A/ko not_active Application Discontinuation
- 2005-12-13 TW TW094143956A patent/TW200714716A/zh unknown
-
2008
- 2008-02-24 IL IL189705A patent/IL189705A0/en unknown
- 2008-03-06 NO NO20081198A patent/NO20081198L/no not_active Application Discontinuation
- 2008-04-07 US US12/080,959 patent/US20080286785A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005337051A1 (en) | 2007-04-12 |
| CA2624613A1 (en) | 2007-04-12 |
| EP1931798A1 (en) | 2008-06-18 |
| IL189705A0 (en) | 2008-06-05 |
| NZ566387A (en) | 2010-05-28 |
| KR20080028857A (ko) | 2008-04-01 |
| US20080286785A1 (en) | 2008-11-20 |
| BRPI0520530A2 (pt) | 2009-09-29 |
| JP2009511008A (ja) | 2009-03-19 |
| CN101351563A (zh) | 2009-01-21 |
| TW200714716A (en) | 2007-04-16 |
| NO20081198L (no) | 2008-06-30 |
| WO2007039705A1 (en) | 2007-04-12 |
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