ZA200802645B - Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia - Google Patents

Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia

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Publication number
ZA200802645B
ZA200802645B ZA200802645A ZA200802645A ZA200802645B ZA 200802645 B ZA200802645 B ZA 200802645B ZA 200802645 A ZA200802645 A ZA 200802645A ZA 200802645 A ZA200802645 A ZA 200802645A ZA 200802645 B ZA200802645 B ZA 200802645B
Authority
ZA
South Africa
Prior art keywords
functional
ibs
treatment
compounds useful
gastrointestinal disorders
Prior art date
Application number
ZA200802645A
Other languages
English (en)
Inventor
Bergman Rolf
Von Unge Sverker
Holmqvist Sara
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200802645B publication Critical patent/ZA200802645B/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

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  • Obesity (AREA)
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ZA200802645A 2005-09-29 2008-03-25 Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia ZA200802645B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0502150 2005-09-29

Publications (1)

Publication Number Publication Date
ZA200802645B true ZA200802645B (en) 2008-12-31

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ZA200802645A ZA200802645B (en) 2005-09-29 2008-03-25 Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia

Country Status (16)

Country Link
US (1) US8288370B2 (zh)
EP (1) EP1940845B1 (zh)
JP (1) JP5139985B2 (zh)
KR (1) KR20080077096A (zh)
CN (1) CN101316846A (zh)
AR (1) AR057828A1 (zh)
AU (1) AU2006295473B2 (zh)
BR (1) BRPI0616581A2 (zh)
CA (1) CA2624491C (zh)
ES (1) ES2426259T3 (zh)
HK (1) HK1121142A1 (zh)
NO (1) NO20081983L (zh)
TW (1) TW200745122A (zh)
UY (1) UY29818A1 (zh)
WO (1) WO2007037743A1 (zh)
ZA (1) ZA200802645B (zh)

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CN104958297A (zh) * 2015-06-03 2015-10-07 周玉梅 一种用于麻醉镇静催眠的药物组合物及其应用
CN105663133B (zh) * 2016-03-07 2019-06-25 青岛市肿瘤医院 一种抑制淋巴瘤细胞增殖的药物组合物及其应用
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EP1940845A4 (en) 2010-11-17
CA2624491A1 (en) 2007-04-05
CN101316846A (zh) 2008-12-03
BRPI0616581A2 (pt) 2011-06-21
US20100311713A1 (en) 2010-12-09
US8288370B2 (en) 2012-10-16
HK1121142A1 (en) 2009-04-17
AU2006295473A1 (en) 2007-04-05
CA2624491C (en) 2014-01-14
NO20081983L (no) 2008-06-27
EP1940845A1 (en) 2008-07-09
UY29818A1 (es) 2007-04-30
AU2006295473B2 (en) 2011-11-10
JP2009510055A (ja) 2009-03-12
TW200745122A (en) 2007-12-16
JP5139985B2 (ja) 2013-02-06
AR057828A1 (es) 2007-12-19
ES2426259T3 (es) 2013-10-22
KR20080077096A (ko) 2008-08-21
WO2007037743A1 (en) 2007-04-05
EP1940845B1 (en) 2013-06-12

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