HK1121142A1 - Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia - Google Patents
Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsiaInfo
- Publication number
- HK1121142A1 HK1121142A1 HK09100247.2A HK09100247A HK1121142A1 HK 1121142 A1 HK1121142 A1 HK 1121142A1 HK 09100247 A HK09100247 A HK 09100247A HK 1121142 A1 HK1121142 A1 HK 1121142A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- functional
- ibs
- treatment
- compounds useful
- gastrointestinal disorders
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
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- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0502150 | 2005-09-29 | ||
PCT/SE2006/001092 WO2007037743A1 (en) | 2005-09-29 | 2006-09-27 | Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1121142A1 true HK1121142A1 (en) | 2009-04-17 |
Family
ID=37900052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09100247.2A HK1121142A1 (en) | 2005-09-29 | 2009-02-03 | Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia |
Country Status (16)
Country | Link |
---|---|
US (1) | US8288370B2 (xx) |
EP (1) | EP1940845B1 (xx) |
JP (1) | JP5139985B2 (xx) |
KR (1) | KR20080077096A (xx) |
CN (1) | CN101316846A (xx) |
AR (1) | AR057828A1 (xx) |
AU (1) | AU2006295473B2 (xx) |
BR (1) | BRPI0616581A2 (xx) |
CA (1) | CA2624491C (xx) |
ES (1) | ES2426259T3 (xx) |
HK (1) | HK1121142A1 (xx) |
NO (1) | NO20081983L (xx) |
TW (1) | TW200745122A (xx) |
UY (1) | UY29818A1 (xx) |
WO (1) | WO2007037743A1 (xx) |
ZA (1) | ZA200802645B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8106208B2 (en) * | 2006-05-18 | 2012-01-31 | Albireo Ab | Benzamide compounds that act as NK receptor antagonists |
WO2007136326A2 (en) * | 2006-05-18 | 2007-11-29 | Astrazeneca Ab | ) t e text as een esta s e y t s ut o ty to rea as o ows: 1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 3 |
WO2007136325A1 (en) * | 2006-05-18 | 2007-11-29 | Astrazeneca Ab | 1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 2 |
WO2008076042A1 (en) * | 2006-12-19 | 2008-06-26 | Astrazeneca Ab | Azetidinpiperazine derivatives that are neurokinin (nk) receptor antagonists and their use. |
WO2008118091A1 (en) * | 2007-03-28 | 2008-10-02 | Albireo Ab | A fumarate salt of 3-bromo-n-{ (2s) -2- (4 -fluorophenyl) -4- [3- (4-acetylpiperazin-l-yl) azetidin-1-yl] butyl} -n-methyl-5- (trifluoromethyl)benzamide for the treatment of gastrointestinal disorders |
WO2008118092A1 (en) * | 2007-03-28 | 2008-10-02 | Albireo Ab | Maleate salt of 3-bromo-n-{ (2s) -2- (4-f luorophenyl) -4- [3- (4-acetylpiperazin-1-yl) azetidin-1-yl] butyl} -methyl-5- (trifluoromethyl)benzamide for the treatment of gastrointestinal disorders |
PL2098526T3 (pl) * | 2008-02-22 | 2014-06-30 | Neurotune Ag | Bicykliczne związki zawierające azot aktywne w stanach przewlekłego bólu |
US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
JP2013518085A (ja) | 2010-02-01 | 2013-05-20 | ノバルティス アーゲー | CRF−1受容体アンタゴニストとしてのピラゾロ[5,1b]オキサゾール誘導体 |
WO2011092293A2 (en) | 2010-02-01 | 2011-08-04 | Novartis Ag | Cyclohexyl amide derivatives as crf receptor antagonists |
WO2011095450A1 (en) | 2010-02-02 | 2011-08-11 | Novartis Ag | Cyclohexyl amide derivatives as crf receptor antagonists |
CN104906106A (zh) * | 2015-04-23 | 2015-09-16 | 谭作华 | 一种抗肿瘤细胞增殖的药物组合物及其应用 |
CN104873482B (zh) * | 2015-05-05 | 2017-12-01 | 青岛市市立医院 | 一种抗慢性心力衰竭的药物组合物 |
CN104958297A (zh) * | 2015-06-03 | 2015-10-07 | 周玉梅 | 一种用于麻醉镇静催眠的药物组合物及其应用 |
CN105663133B (zh) * | 2016-03-07 | 2019-06-25 | 青岛市肿瘤医院 | 一种抑制淋巴瘤细胞增殖的药物组合物及其应用 |
MX2018010856A (es) * | 2016-03-09 | 2019-07-10 | Biomerica Inc | Composiciones, dispositivos y metodos de pruebas de sensibilidad de dispepsia funcional. |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9310066D0 (en) | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Alkyl substituted heterocycles |
GB9310713D0 (en) | 1993-05-24 | 1993-07-07 | Zeneca Ltd | Aryl substituted heterocycles |
GB9317104D0 (en) | 1993-08-17 | 1993-09-29 | Zeneca Ltd | Therapeutic heterocycles |
GB9322643D0 (en) | 1993-11-03 | 1993-12-22 | Zeneca Ltd | Lactam derivatives |
GB9325074D0 (en) | 1993-12-07 | 1994-02-02 | Zeneca Ltd | Bicyclic heterocycles |
TW432061B (en) | 1994-08-09 | 2001-05-01 | Pfizer Res & Dev | Lactams |
US5607936A (en) | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
GB9502644D0 (en) | 1995-02-10 | 1995-03-29 | Zeneca Ltd | Heterocyclic derivatives |
ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
GB9600235D0 (en) | 1996-01-05 | 1996-03-06 | Pfizer Ltd | Therapeutic agents |
GB9601202D0 (en) | 1996-01-22 | 1996-03-20 | Pfizer Ltd | Piperidones |
GB9601697D0 (en) | 1996-01-27 | 1996-03-27 | Pfizer Ltd | Therapeutic agents |
GB9601680D0 (en) | 1996-01-27 | 1996-03-27 | Pfizer Ltd | Therapeutic agents |
US6013652A (en) * | 1997-12-04 | 2000-01-11 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin antagonists |
GB9812037D0 (en) | 1998-06-04 | 1998-07-29 | Pfizer Ltd | Piperidones |
US6365602B1 (en) | 1998-07-10 | 2002-04-02 | Astra Zeneca Ab | N-substituted naphthalene carboxamides as neurokinin-receptor antagonists |
GB9922519D0 (en) | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
GB9922521D0 (en) | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
GB9924141D0 (en) | 1998-10-30 | 1999-12-15 | Zeneca Ltd | Treatment of gastric asthma |
GB9826941D0 (en) * | 1998-12-09 | 1999-02-03 | Zeneca Pharmaceuticals | Compounds |
SE0000772D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
JP2004501903A (ja) * | 2000-06-29 | 2004-01-22 | 藤沢薬品工業株式会社 | ベンズヒドリル誘導体 |
EG26979A (en) * | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
SE0004827D0 (sv) | 2000-12-22 | 2000-12-22 | Astrazeneca Ab | Therapeutic compounds |
GB0121337D0 (en) * | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
GB0121622D0 (en) * | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
GB0121621D0 (en) * | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
MXPA04002179A (es) * | 2001-09-08 | 2004-06-29 | Astrazeneca Ab | Derivados de benzotiazepina y benzotiadiazepina con actividad inhibidora de transporte del acido ileal biliar (ibat) para tratar hiperlipidemia. |
SE0103795D0 (sv) | 2001-11-02 | 2001-11-02 | Astrazeneca Ab | Compounds and method for the treatment of överactive bladder |
GB0203020D0 (en) | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
GB0209467D0 (en) * | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
GB0213669D0 (en) * | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
GB0216321D0 (en) * | 2002-07-13 | 2002-08-21 | Astrazeneca Ab | Therapeutic treatment |
US7247725B2 (en) * | 2002-10-30 | 2007-07-24 | Merck & Co., Inc. | Gamma-aminoamide modulators of chemokine receptor activity |
GB0304194D0 (en) * | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
GB0307918D0 (en) * | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
TW200508221A (en) * | 2003-06-13 | 2005-03-01 | Astrazeneca Ab | New azetidine compounds |
GB0406342D0 (en) * | 2004-03-20 | 2004-04-21 | Astrazeneca Ab | Molecules |
GB0509405D0 (en) * | 2005-05-10 | 2005-06-15 | Merck Sharp & Dohme | Therapeutic compounds |
CN101208327A (zh) | 2005-06-23 | 2008-06-25 | 阿斯利康(瑞典)有限公司 | 作为神经激肽受体拮抗剂用于治疗胃肠疾病的新氮杂环丁烷衍生物 |
AU2006259891A1 (en) * | 2005-06-23 | 2006-12-28 | Albireo Ab | New azetidine derivatives as neurokinin receptor antagonists for the treatment of gastrointestinal diseases |
WO2007136325A1 (en) * | 2006-05-18 | 2007-11-29 | Astrazeneca Ab | 1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 2 |
US8106208B2 (en) * | 2006-05-18 | 2012-01-31 | Albireo Ab | Benzamide compounds that act as NK receptor antagonists |
WO2007136326A2 (en) * | 2006-05-18 | 2007-11-29 | Astrazeneca Ab | ) t e text as een esta s e y t s ut o ty to rea as o ows: 1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 3 |
WO2008076041A1 (en) * | 2006-12-19 | 2008-06-26 | Albireo Ab | Azetidinazabicyclo [3.2.1] octan derivatives that are neurokinin (nk) receptor antagonists and their use. |
-
2006
- 2006-09-25 AR ARP060104172A patent/AR057828A1/es not_active Application Discontinuation
- 2006-09-27 AU AU2006295473A patent/AU2006295473B2/en not_active Ceased
- 2006-09-27 CN CNA2006800442320A patent/CN101316846A/zh active Pending
- 2006-09-27 JP JP2008533288A patent/JP5139985B2/ja not_active Expired - Fee Related
- 2006-09-27 CA CA2624491A patent/CA2624491C/en not_active Expired - Fee Related
- 2006-09-27 US US11/992,701 patent/US8288370B2/en not_active Expired - Fee Related
- 2006-09-27 ES ES06784202T patent/ES2426259T3/es active Active
- 2006-09-27 BR BRPI0616581-8A patent/BRPI0616581A2/pt not_active IP Right Cessation
- 2006-09-27 WO PCT/SE2006/001092 patent/WO2007037743A1/en active Application Filing
- 2006-09-27 EP EP06784202.1A patent/EP1940845B1/en not_active Not-in-force
- 2006-09-27 KR KR1020087010177A patent/KR20080077096A/ko not_active Application Discontinuation
- 2006-09-28 UY UY29818A patent/UY29818A1/es unknown
- 2006-09-29 TW TW095136161A patent/TW200745122A/zh unknown
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2008
- 2008-03-25 ZA ZA200802645A patent/ZA200802645B/xx unknown
- 2008-04-25 NO NO20081983A patent/NO20081983L/no not_active Application Discontinuation
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2009
- 2009-02-03 HK HK09100247.2A patent/HK1121142A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1940845A1 (en) | 2008-07-09 |
TW200745122A (en) | 2007-12-16 |
AU2006295473A1 (en) | 2007-04-05 |
UY29818A1 (es) | 2007-04-30 |
US8288370B2 (en) | 2012-10-16 |
EP1940845B1 (en) | 2013-06-12 |
BRPI0616581A2 (pt) | 2011-06-21 |
CA2624491A1 (en) | 2007-04-05 |
WO2007037743A1 (en) | 2007-04-05 |
CA2624491C (en) | 2014-01-14 |
JP5139985B2 (ja) | 2013-02-06 |
JP2009510055A (ja) | 2009-03-12 |
KR20080077096A (ko) | 2008-08-21 |
CN101316846A (zh) | 2008-12-03 |
ES2426259T3 (es) | 2013-10-22 |
AU2006295473B2 (en) | 2011-11-10 |
EP1940845A4 (en) | 2010-11-17 |
US20100311713A1 (en) | 2010-12-09 |
NO20081983L (no) | 2008-06-27 |
AR057828A1 (es) | 2007-12-19 |
ZA200802645B (en) | 2008-12-31 |
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Effective date: 20170927 |