ZA200711080B - 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus - Google Patents
1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virusInfo
- Publication number
- ZA200711080B ZA200711080B ZA200711080A ZA200711080A ZA200711080B ZA 200711080 B ZA200711080 B ZA 200711080B ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 A ZA200711080 A ZA 200711080A ZA 200711080 B ZA200711080 B ZA 200711080B
- Authority
- ZA
- South Africa
- Prior art keywords
- substituted
- 6alkyl
- benzimidazoilymethyl
- benzoimidazol
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05076438 | 2005-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200711080B true ZA200711080B (en) | 2009-03-25 |
Family
ID=35276402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200711080A ZA200711080B (en) | 2005-06-20 | 2007-12-19 | 1-(2-amino-3-(substituted alkyl)-3H-benzimidazoilymethyl)-3-substituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8034835B2 (xx) |
| EP (1) | EP1896473B1 (xx) |
| JP (1) | JP5078887B2 (xx) |
| CN (1) | CN101203517B (xx) |
| AT (1) | ATE529424T1 (xx) |
| AU (1) | AU2006260969B2 (xx) |
| BR (1) | BRPI0612628B8 (xx) |
| CA (1) | CA2612263C (xx) |
| MX (1) | MX2007016537A (xx) |
| RU (1) | RU2434000C2 (xx) |
| WO (1) | WO2006136561A1 (xx) |
| ZA (1) | ZA200711080B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007085357A1 (en) * | 2006-01-30 | 2007-08-02 | Euro-Celtique S.A. | Cyclourea compounds as calcium channel blockers |
| TWI650321B (zh) | 2011-10-14 | 2019-02-11 | 美商安比特生物科學公司 | 雜環化合物及其使用方法 |
| SG11201600977XA (en) | 2013-08-21 | 2016-03-30 | Alios Biopharma Inc | Antiviral compounds |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| JO3637B1 (ar) * | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
| US10881666B2 (en) | 2017-09-29 | 2021-01-05 | Enanta Pharmaceuticals, Inc. | Combination pharmaceutical agents as RSV inhibitors |
| TW201932470A (zh) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | 具有抗ｒｓｖ活性之吡唑并嘧啶 |
| KR20200116099A (ko) | 2018-01-31 | 2020-10-08 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | Rsv에 대한 활성을 갖는 시클로알킬 치환 피라졸로피리미딘 |
| MA52348A (fr) | 2018-04-23 | 2021-03-03 | Janssen Sciences Ireland Unlimited Co | Composés hétéroaromatiques ayant une activité contre vrs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2376785A1 (en) | 1999-06-28 | 2001-01-04 | Janssen Pharmaceutica N.V. | Benzimidazoles and imidazopyridines as respiratory syncytial virus replication inhibitors |
| SK18942001A3 (sk) | 1999-06-28 | 2002-10-08 | Janssen Pharmaceutica N. V. | Inhibítory replikácie respiračného syncytiálneho vírusu |
| UA74787C2 (en) | 1999-06-28 | 2006-02-15 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
| US6489338B2 (en) | 2000-06-13 | 2002-12-03 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrimidine antiviral agents |
| AR046959A1 (es) * | 2003-12-18 | 2006-01-04 | Tibotec Pharm Ltd | Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio |
| BRPI0417811A (pt) * | 2003-12-18 | 2007-03-27 | Tibotec Pharm Ltd | aminobenzimidazóis e benzimidazóis como inibidores da replicação do vìrus sincicial respiratório |
-
2006
- 2006-06-20 RU RU2008102057/04A patent/RU2434000C2/ru active
- 2006-06-20 AT AT06763808T patent/ATE529424T1/de not_active IP Right Cessation
- 2006-06-20 EP EP06763808A patent/EP1896473B1/en active Active
- 2006-06-20 WO PCT/EP2006/063365 patent/WO2006136561A1/en active Application Filing
- 2006-06-20 US US11/993,109 patent/US8034835B2/en active Active
- 2006-06-20 CN CN2006800219722A patent/CN101203517B/zh active Active
- 2006-06-20 MX MX2007016537A patent/MX2007016537A/es active IP Right Grant
- 2006-06-20 AU AU2006260969A patent/AU2006260969B2/en not_active Ceased
- 2006-06-20 JP JP2008517487A patent/JP5078887B2/ja active Active
- 2006-06-20 BR BRPI0612628A patent/BRPI0612628B8/pt not_active IP Right Cessation
- 2006-06-20 CA CA2612263A patent/CA2612263C/en active Active
-
2007
- 2007-12-19 ZA ZA200711080A patent/ZA200711080B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006260969A1 (en) | 2006-12-28 |
| CN101203517B (zh) | 2011-07-06 |
| JP5078887B2 (ja) | 2012-11-21 |
| RU2434000C2 (ru) | 2011-11-20 |
| BRPI0612628B8 (pt) | 2021-05-25 |
| MX2007016537A (es) | 2008-03-06 |
| RU2008102057A (ru) | 2009-07-27 |
| ATE529424T1 (de) | 2011-11-15 |
| US8034835B2 (en) | 2011-10-11 |
| BRPI0612628B1 (pt) | 2019-12-03 |
| CN101203517A (zh) | 2008-06-18 |
| WO2006136561A1 (en) | 2006-12-28 |
| JP2008546738A (ja) | 2008-12-25 |
| CA2612263A1 (en) | 2006-12-28 |
| CA2612263C (en) | 2015-04-14 |
| EP1896473A1 (en) | 2008-03-12 |
| US20100183552A1 (en) | 2010-07-22 |
| EP1896473B1 (en) | 2011-10-19 |
| AU2006260969B2 (en) | 2011-11-17 |
| BRPI0612628A2 (pt) | 2012-01-03 |
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