ZA200710582B - Imidazole based LXR modulators - Google Patents

Imidazole based LXR modulators

Info

Publication number
ZA200710582B
ZA200710582B ZA200710582A ZA200710582A ZA200710582B ZA 200710582 B ZA200710582 B ZA 200710582B ZA 200710582 A ZA200710582 A ZA 200710582A ZA 200710582 A ZA200710582 A ZA 200710582A ZA 200710582 B ZA200710582 B ZA 200710582B
Authority
ZA
South Africa
Prior art keywords
lxr modulators
imidazole based
based lxr
imidazole
modulators
Prior art date
Application number
ZA200710582A
Other languages
English (en)
Inventor
Brett B Busch
Gu Xiao-Hui
Martin Richard
Nyman Michael Charles
William C Stevens Jr
Xie Yinong
Brenton T Flatt
Lu Shao-Po
Mohan Raju
Schweiger Edwin
Wang Tie-Lin
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of ZA200710582B publication Critical patent/ZA200710582B/xx

Links

ZA200710582A 2005-06-27 2007-12-05 Imidazole based LXR modulators ZA200710582B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69437205P 2005-06-27 2005-06-27

Publications (1)

Publication Number Publication Date
ZA200710582B true ZA200710582B (en) 2008-12-31

Family

ID=39947886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200710582A ZA200710582B (en) 2005-06-27 2007-12-05 Imidazole based LXR modulators

Country Status (3)

Country Link
CN (2) CN101248049B (xx)
SG (1) SG162803A1 (xx)
ZA (1) ZA200710582B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2620451T3 (es) * 2009-05-28 2017-06-28 Exelixis Patent Company Llc Moduladores de los LXR
EP2395003A1 (en) * 2010-05-27 2011-12-14 Laboratorios Del. Dr. Esteve, S.A. Pyrazole compounds as sigma receptor inhibitors
AR088728A1 (es) * 2011-03-25 2014-07-02 Bristol Myers Squibb Co Moduladores de lxr como prodroga de imidazol
HUE040231T2 (hu) 2012-03-02 2019-02-28 Ralexar Therapeutics Inc Máj X receptor (LXR) modulátorok bõrbetegségek, rendellenességek és állapotok kezelésére
CA2923178A1 (en) 2013-09-04 2015-03-12 Alexar Therapeutics, Inc. Liver x receptor (lxr) modulators for the treatment of dermal diseases, disorders and conditions
ES2804304T3 (es) 2013-09-04 2021-02-05 Ellora Therapeutics Inc Moduladores del receptor X hepático (LXR)
WO2016131810A1 (en) * 2015-02-20 2016-08-25 Bayer Pharma Aktiengesellschaft N-phenyl-(morpholin-4-yl or piperazinyl)acetamide derivatives and their use as inhibitors of the wnt signalling pathways
CN105001210B (zh) * 2015-07-06 2017-11-28 南京大学 一类含甲硝唑骨架的吡唑硝基咪唑衍生物、其制备方法及应用
CN106543092B (zh) * 2016-10-14 2019-05-17 华东师范大学 1,5-二芳香基-1,2,4-三氮唑类化合物及其制药用途
EA202091101A1 (ru) * 2017-11-01 2020-08-06 Бристол-Маерс Сквибб Компани Спироциклические соединения в качестве модуляторов фарнезоидного x-рецептора
CN113527281B (zh) * 2020-04-20 2023-12-22 昆山彭济凯丰生物科技有限公司 杂环化合物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2179254T3 (es) * 1996-11-04 2003-01-16 Bayer Cropscience Sa 1-poliarilpirazoles plaguicidas.
WO2004011446A1 (en) * 2002-07-26 2004-02-05 Bayer Pharmaceuticals Corporation Indane, dihydrobenzofuran, and tetrahydronaphthalene carboxylic acid derivatives and their use as antidiabetics
TWI324596B (en) * 2002-08-26 2010-05-11 Nat Health Research Institutes Imidazolamino compounds
CN1747936A (zh) * 2003-02-12 2006-03-15 特兰斯泰克制药公司 作为治疗试剂的取代吡咯衍生物
DE10315573A1 (de) * 2003-04-05 2004-10-14 Merck Patent Gmbh Substituierte Pyrazole
PT1638943E (pt) * 2003-05-27 2008-11-14 Conseils De Rech S Et D Aplica Novos derivados de imidazoles, sua preparação e sua utilização como medicamento
US20090018150A1 (en) * 2003-07-24 2009-01-15 Asterand Uk Limited 5-Ht2b Receptor Antagonists
JP2006528661A (ja) * 2003-07-25 2006-12-21 ファイザー・インク アミノピラゾール化合物およびｃｈｋ１阻害剤としての使用
US8969372B2 (en) * 2003-11-14 2015-03-03 Aptose Boisciences Inc. Aryl imidazoles and their use as anti-cancer agents

Also Published As

Publication number Publication date
CN101248049A (zh) 2008-08-20
CN101248048B (zh) 2013-08-28
CN101248049B (zh) 2013-08-28
CN101248048A (zh) 2008-08-20
SG162803A1 (en) 2010-07-29

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