SG162803A1 - Imidazole based lxr modulators - Google Patents
Imidazole based lxr modulatorsInfo
- Publication number
- SG162803A1 SG162803A1 SG201004272-9A SG2010042729A SG162803A1 SG 162803 A1 SG162803 A1 SG 162803A1 SG 2010042729 A SG2010042729 A SG 2010042729A SG 162803 A1 SG162803 A1 SG 162803A1
- Authority
- SG
- Singapore
- Prior art keywords
- compounds
- lxr modulators
- imidazole based
- based lxr
- modulators
- Prior art date
Links
Abstract
Compounds of the invention, such as compounds of Formulae IIa, IIb, Ile or IId, and pharmaceutically acceptable salts, isomers, and prodrugs thereof, are useful as modulators of the activity of liver X receptors, where R1, R2, R21, R3 and G are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed. (No suitable figure)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69437205P | 2005-06-27 | 2005-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG162803A1 true SG162803A1 (en) | 2010-07-29 |
Family
ID=39947886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG201004272-9A SG162803A1 (en) | 2005-06-27 | 2006-06-26 | Imidazole based lxr modulators |
Country Status (3)
Country | Link |
---|---|
CN (2) | CN101248049B (en) |
SG (1) | SG162803A1 (en) |
ZA (1) | ZA200710582B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5625050B2 (en) * | 2009-05-28 | 2014-11-12 | エグゼリクシス パテント カンパニー エルエルシー | LXR regulators |
EP2395003A1 (en) * | 2010-05-27 | 2011-12-14 | Laboratorios Del. Dr. Esteve, S.A. | Pyrazole compounds as sigma receptor inhibitors |
TW201242953A (en) * | 2011-03-25 | 2012-11-01 | Bristol Myers Squibb Co | Imidazole prodrug LXR modulators |
SG10201607345YA (en) * | 2012-03-02 | 2016-11-29 | Ralexar Therapeutics Inc | Liver x receptor (lxr) modulators for the treatment of dermal diseases, disorders and conditions |
MX371343B (en) | 2013-09-04 | 2020-01-27 | Ralexar Therapeutics Inc | Liver x receptor (lxr) modulators. |
EP3041834A4 (en) | 2013-09-04 | 2017-01-18 | Ralexar Therapeutics, Inc. | Liver x receptor (lxr) modulators |
CA2976973A1 (en) * | 2015-02-20 | 2016-08-25 | Bayer Pharma Aktiengesellschaft | N-phenyl-(morpholin-4-yl or piperazinyl)acetamide derivatives and their use as inhibitors of the wnt signalling pathways |
CN105001210B (en) * | 2015-07-06 | 2017-11-28 | 南京大学 | Pyrazoles nitro imidazole derivatives, its preparation method and the application of a kind of skeleton containing metronidazole |
CN106543092B (en) * | 2016-10-14 | 2019-05-17 | 华东师范大学 | Bis- aromatic radical -1,2,4- triazole compound of 1,5- and its pharmaceutical applications |
MX2020004400A (en) * | 2017-11-01 | 2020-08-06 | Bristol Myers Squibb Co | Spirocyclic compounds as farnesoid x receptor modulators. |
CN113527281B (en) * | 2020-04-20 | 2023-12-22 | 昆山彭济凯丰生物科技有限公司 | Heterocyclic compounds, process for their preparation and their use |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2179254T3 (en) * | 1996-11-04 | 2003-01-16 | Bayer Cropscience Sa | 1-PESTICIDE POLYARILPIRAZOLES. |
WO2004011446A1 (en) * | 2002-07-26 | 2004-02-05 | Bayer Pharmaceuticals Corporation | Indane, dihydrobenzofuran, and tetrahydronaphthalene carboxylic acid derivatives and their use as antidiabetics |
US7109227B2 (en) * | 2002-08-26 | 2006-09-19 | National Health Research Institutes | Imidazolamino compounds |
JP2006518738A (en) * | 2003-02-12 | 2006-08-17 | トランス テック ファーマ,インコーポレイテッド | Substituted azole derivatives as therapeutic agents |
DE10315573A1 (en) * | 2003-04-05 | 2004-10-14 | Merck Patent Gmbh | Substituted pyrazoles |
ATE403649T1 (en) * | 2003-05-27 | 2008-08-15 | Sod Conseils Rech Applic | NEW IMIDAZOLE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS A MEDICATION |
US20090018150A1 (en) * | 2003-07-24 | 2009-01-15 | Asterand Uk Limited | 5-Ht2b Receptor Antagonists |
JP2006528661A (en) * | 2003-07-25 | 2006-12-21 | ファイザー・インク | Aminopyrazole compounds and use as CHK1 inhibitors |
EP1692113B1 (en) * | 2003-11-14 | 2017-09-27 | Lorus Therapeutics Inc. | Aryl imidazoles and their use as anti-cancer agents |
-
2006
- 2006-06-26 CN CN200680030791.6A patent/CN101248049B/en active Active
- 2006-06-26 SG SG201004272-9A patent/SG162803A1/en unknown
- 2006-06-26 CN CN200680030647.2A patent/CN101248048B/en not_active Expired - Fee Related
-
2007
- 2007-12-05 ZA ZA200710582A patent/ZA200710582B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN101248048B (en) | 2013-08-28 |
ZA200710582B (en) | 2008-12-31 |
CN101248048A (en) | 2008-08-20 |
CN101248049A (en) | 2008-08-20 |
CN101248049B (en) | 2013-08-28 |
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