ZA200702792B - Improved adenoviral vectors and uses thereof - Google Patents

Improved adenoviral vectors and uses thereof Download PDF

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Publication number
ZA200702792B
ZA200702792B ZA200702792A ZA200702792A ZA200702792B ZA 200702792 B ZA200702792 B ZA 200702792B ZA 200702792 A ZA200702792 A ZA 200702792A ZA 200702792 A ZA200702792 A ZA 200702792A ZA 200702792 B ZA200702792 B ZA 200702792B
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South Africa
Prior art keywords
vectors
seq
serotype
vector
adenovirus
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ZA200702792A
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English (en)
Inventor
Havenga Menzo Jans Emco
Barouch Dan
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Crucell Holland Bv
Beth Israel Hospital
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Publication of ZA200702792B publication Critical patent/ZA200702792B/en

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    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2710/10011Adenoviridae
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    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/10345Special targeting system for viral vectors
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    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6009Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
    • C12N2810/6018Adenoviridae

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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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ZA200702792A 2004-10-13 2007-04-03 Improved adenoviral vectors and uses thereof ZA200702792B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04105005 2004-10-13

Publications (1)

Publication Number Publication Date
ZA200702792B true ZA200702792B (en) 2007-12-27

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ID=34929696

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200702792A ZA200702792B (en) 2004-10-13 2007-04-03 Improved adenoviral vectors and uses thereof

Country Status (6)

Country Link
JP (1) JP4843613B2 (de)
CN (1) CN101072879B (de)
AT (1) ATE492643T1 (de)
DE (1) DE602005025512D1 (de)
ES (1) ES2358523T3 (de)
ZA (1) ZA200702792B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085984A1 (en) * 2009-02-02 2010-08-05 Okairos Ag Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof
WO2011022002A1 (en) * 2009-08-18 2011-02-24 The Rockefeller University Modification of recombinant adenovirus with immunogenic plasmodium circumsporozoite protein epitopes
US20130058897A1 (en) * 2010-04-14 2013-03-07 Mogam Biotechnology Research Institute Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same
WO2012082918A1 (en) * 2010-12-14 2012-06-21 The Goverment Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Adenovirus serotype 26 and serotype 35 filovirus vaccines
CN102199616B (zh) * 2011-03-07 2013-04-24 首都医科大学附属北京佑安医院 Hiv-1表型耐药检测载体及其构建方法
JP6757120B2 (ja) * 2011-10-05 2020-09-16 ジェンヴェック エルエルシー アーフェンアデノウイルス(ゴリラ)又はアデノウイルスベクター、及び使用方法
CN104334188B (zh) * 2012-03-22 2016-08-24 克鲁塞尔荷兰公司 抗rsv疫苗
EP3328402A4 (de) * 2015-07-28 2019-04-03 The Trustees Of The University Of Pennsylvania Chimäre antigenrezeptoren exprimierende modifizierte monozyten/makrophagen und verwendungen davon
AU2017375633C1 (en) * 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN106868047B (zh) * 2017-03-07 2020-04-28 南方医科大学 一种重组腺病毒载体及其构建方法和用途
BR112020000145A2 (pt) * 2017-07-05 2020-07-14 Nouscom Ag polinucleotídeos, adenovírus isolado, partícula semelhante a vírus, vetor, composição, célula e método in vitro para a produção de um adenovírus ou de uma partícula semelhante a adenovírus
CN107267469B (zh) * 2017-08-22 2020-06-16 广州医科大学附属第一医院 纤毛蛋白嵌合型重组人b型腺病毒及其制备方法
CA3077630A1 (en) * 2017-10-31 2019-05-09 Janssen Vaccines & Prevention B.V. Adenovirus vectors and uses thereof
MA50502A (fr) * 2017-10-31 2020-09-09 Janssen Vaccines & Prevention Bv Adénovirus et utilisations associées
US20210371471A1 (en) * 2018-04-03 2021-12-02 Stridebio, Inc. Antibody-evading virus vectors
JP7319368B2 (ja) * 2018-11-21 2023-08-01 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ アデノウイルスおよびアデノウイルスを使用するための方法
EP3927833A4 (de) * 2019-02-21 2022-11-30 Unleash Immuno Oncolytics, Inc. Onkolytischer adenoviraler vektor und verfahren zur verwendung
CA3184807A1 (en) 2020-06-04 2021-12-09 Carisma Therapeutics Inc. Novel constructs for chimeric antigen receptors
CN114262692A (zh) * 2021-11-30 2022-04-01 华中科技大学同济医学院附属同济医院 一种携带tmvp1和hsv-tk的溶瘤腺病毒重组体,其构建方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127525A (en) * 1995-02-21 2000-10-03 Cornell Research Foundation, Inc. Chimeric adenoviral coat protein and methods of using same
US5922315A (en) * 1997-01-24 1999-07-13 Genetic Therapy, Inc. Adenoviruses having altered hexon proteins
ATE530672T1 (de) * 2001-06-22 2011-11-15 Univ Pennsylvania Rekombinante adenoviren mit affen-adenovirus proteinen und verwendung davon.

Also Published As

Publication number Publication date
JP2009523007A (ja) 2009-06-18
ATE492643T1 (de) 2011-01-15
CN101072879A (zh) 2007-11-14
ES2358523T3 (es) 2011-05-11
CN101072879B (zh) 2011-05-11
JP4843613B2 (ja) 2011-12-21
DE602005025512D1 (de) 2011-02-03

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