ZA200702701B - Phenanthridine carbonyl phenols as cytokine modulators - Google Patents

Phenanthridine carbonyl phenols as cytokine modulators

Info

Publication number
ZA200702701B
ZA200702701B ZA200702701A ZA200702701A ZA200702701B ZA 200702701 B ZA200702701 B ZA 200702701B ZA 200702701 A ZA200702701 A ZA 200702701A ZA 200702701 A ZA200702701 A ZA 200702701A ZA 200702701 B ZA200702701 B ZA 200702701B
Authority
ZA
South Africa
Prior art keywords
cytokine modulators
phenols
phenanthridine
phenanthridine carbonyl
carbonyl phenols
Prior art date
Application number
ZA200702701A
Other languages
English (en)
Inventor
Steffan Robert John
Eugene J Trybulski
Moore William Jay
Molinari Albert John
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35447362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200702701(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200702701B publication Critical patent/ZA200702701B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200702701A 2004-09-02 2007-03-30 Phenanthridine carbonyl phenols as cytokine modulators ZA200702701B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60678404P 2004-09-02 2004-09-02

Publications (1)

Publication Number Publication Date
ZA200702701B true ZA200702701B (en) 2009-10-28

Family

ID=35447362

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200702701A ZA200702701B (en) 2004-09-02 2007-03-30 Phenanthridine carbonyl phenols as cytokine modulators

Country Status (19)

Country Link
US (1) US7585871B2 (ja)
EP (1) EP1784391A1 (ja)
JP (1) JP2008511666A (ja)
KR (1) KR20070051877A (ja)
CN (1) CN101052623A (ja)
AR (1) AR050719A1 (ja)
AU (1) AU2005282829A1 (ja)
BR (1) BRPI0514860A (ja)
CA (1) CA2578933A1 (ja)
CR (1) CR8946A (ja)
EC (1) ECSP077366A (ja)
IL (1) IL181585A0 (ja)
MX (1) MX2007002624A (ja)
NI (1) NI200700066A (ja)
NO (1) NO20071439L (ja)
RU (1) RU2007108713A (ja)
TW (1) TW200616629A (ja)
WO (1) WO2006028875A1 (ja)
ZA (1) ZA200702701B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103588776B (zh) * 2011-12-22 2016-03-02 华中科技大学 葱莲中具有抗肿瘤作用的化合物及其分离制备方法和应用
JP2019536797A (ja) * 2016-12-06 2019-12-19 バローベック，ソシエテ エン コマンディテ 癌の処置のためのチエノイソキノリンおよびその誘導体
JP7061772B2 (ja) * 2018-05-18 2022-05-02 国立大学法人千葉大学 フェナントリジン化合物の製造方法
WO2020117894A1 (en) * 2018-12-05 2020-06-11 The Board Of Trustees Of The University Of Illinois Isocarbostyril alkaloids and functionalization thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206225A (en) 1978-09-22 1980-06-03 Pfizer Inc. 2,10-Disubstituted dibenzo[b,d]pyrans and benzo[c]quinolines
US4228169A (en) 1979-06-26 1980-10-14 Pfizer Inc. 1,9-Dihydroxyoctahydrobenzo[c]quinolines and 1-hydroxyhexahydrobenzo[c]quinoline-9(8H)-ones as antiemetic agents
US5869483A (en) 1993-07-29 1999-02-09 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
AU2001281965A1 (en) * 2000-07-14 2002-01-30 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Novel 6-phenylphenanthridines
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
TW200409759A (en) 2002-09-25 2004-06-16 Wyeth Corp Substituted 4-(indazol-3-yl)phenols
US6894061B2 (en) * 2002-12-04 2005-05-17 Wyeth Substituted dihydrophenanthridinesulfonamides

Also Published As

Publication number Publication date
IL181585A0 (en) 2007-07-04
KR20070051877A (ko) 2007-05-18
RU2007108713A (ru) 2008-10-10
CA2578933A1 (en) 2006-03-16
EP1784391A1 (en) 2007-05-16
ECSP077366A (es) 2007-05-30
NI200700066A (es) 2008-02-14
WO2006028875A1 (en) 2006-03-16
NO20071439L (no) 2007-04-23
AU2005282829A1 (en) 2006-03-16
MX2007002624A (es) 2007-04-27
CR8946A (es) 2007-10-04
US7585871B2 (en) 2009-09-08
BRPI0514860A (pt) 2008-06-24
US20060058337A1 (en) 2006-03-16
CN101052623A (zh) 2007-10-10
AR050719A1 (es) 2006-11-15
JP2008511666A (ja) 2008-04-17
TW200616629A (en) 2006-06-01

Similar Documents

Publication Publication Date Title
HK1184738A1 (zh) 注射器組件
IL183278A0 (en) Rod-coupling assemblies
EG24926A (en) An improved spacer
GB0616682D0 (en) Mobile telecommunications
EP1758639A4 (en) BREWER
IL162854A (en) Syringe assembly
PL1827178T3 (pl) Przyrząd do zaparzania
EP1751115A4 (en) THERAMUTEINMODULATOREN
HK1122929A1 (en) Mobile telephone
IL197749A0 (en) Cytokine signaling
IL181120A0 (en) Tricyclic ?? -opioid modulators
EP1940018A4 (en) MF MODULATOR
AU300122S (en) Telephone
EP1863265A4 (en) TELEPHONE APPARATUS
GB0420963D0 (en) Hepatocyte
ZA200702701B (en) Phenanthridine carbonyl phenols as cytokine modulators
GB0621961D0 (en) Mobile telecommunications
GB0501561D0 (en) TS phone
GB0511892D0 (en) Syringe
GB0402654D0 (en) Telecommunications
GB0427954D0 (en) Modulator
GB0417339D0 (en) Syringe
GB0401130D0 (en) Modulators
GB0401131D0 (en) Modulators
IL179559A0 (en) Theramutein modulators