ZA200609846B - Mercaptoimidazoles as CCR2 receptor antagonists - Google Patents
Mercaptoimidazoles as CCR2 receptor antagonistsInfo
- Publication number
- ZA200609846B ZA200609846B ZA200609846A ZA200609846A ZA200609846B ZA 200609846 B ZA200609846 B ZA 200609846B ZA 200609846 A ZA200609846 A ZA 200609846A ZA 200609846 A ZA200609846 A ZA 200609846A ZA 200609846 B ZA200609846 B ZA 200609846B
- Authority
- ZA
- South Africa
- Prior art keywords
- mercaptoimidazoles
- receptor antagonists
- ccr2 receptor
- ccr2
- antagonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61K31/50—Pyridazines; Hydrogenated pyridazines
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- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D233/88—Nitrogen atoms, e.g. allantoin
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2004050933 | 2004-05-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200609846B true ZA200609846B (en) | 2008-07-30 |
Family
ID=34957884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200609846A ZA200609846B (en) | 2004-05-26 | 2006-11-24 | Mercaptoimidazoles as CCR2 receptor antagonists |
Country Status (20)
Country | Link |
---|---|
US (1) | US20070249691A1 (xx) |
EP (1) | EP1753758B1 (xx) |
JP (1) | JP2008500310A (xx) |
KR (1) | KR20070020070A (xx) |
CN (1) | CN1956980A (xx) |
AR (1) | AR049386A1 (xx) |
AT (1) | ATE425161T1 (xx) |
AU (1) | AU2005250156A1 (xx) |
BR (1) | BRPI0511599A (xx) |
CA (1) | CA2566187A1 (xx) |
DE (1) | DE602005013216D1 (xx) |
EA (1) | EA200602193A1 (xx) |
IL (1) | IL179518A0 (xx) |
MX (1) | MXPA06013764A (xx) |
MY (1) | MY140571A (xx) |
NO (1) | NO20066011L (xx) |
PA (1) | PA8634401A1 (xx) |
TW (1) | TW200606154A (xx) |
WO (1) | WO2005118578A1 (xx) |
ZA (1) | ZA200609846B (xx) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070244138A1 (en) * | 2004-05-26 | 2007-10-18 | Janssen Pharmaceutica N.V. | Mercaptoimidazoles as Ccr2 Receptor Antagonists |
ES2764840T3 (es) | 2015-01-28 | 2020-06-04 | Univ Bordeaux | Uso de plerixafor para tratar y/o prevenir exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica |
MX2018014743A (es) * | 2016-06-03 | 2019-04-11 | Chemocentryx Inc | Metodo para tratar fibrosis hepatica. |
EP3833762A4 (en) | 2018-08-09 | 2022-09-28 | Verseau Therapeutics, Inc. | OLIGONUCLEOTIDE COMPOSITIONS FOR TARGETING CCR2 AND CSF1R AND THEIR USES |
CN113412261A (zh) * | 2019-04-08 | 2021-09-17 | 四川科伦博泰生物医药股份有限公司 | 苯并咪唑化合物、其制备方法及其用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1487326A (fr) | 1966-01-18 | 1967-07-07 | Clin Byla Ets | Dérivés imidazoliques et leur préparation |
JPS5343958B2 (xx) | 1972-07-29 | 1978-11-24 | ||
US4770689A (en) * | 1986-03-10 | 1988-09-13 | Janssen Pharmaceutica N.V. | Herbicidal imidazole-5-carboxylic acid derivatives |
DE10107683A1 (de) | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
IL160642A0 (en) * | 2001-10-03 | 2004-07-25 | Ucb Sa | Pyrrolidinone derivatives |
DE10222103A1 (de) * | 2002-05-17 | 2003-11-27 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
WO2004069809A1 (en) | 2003-02-03 | 2004-08-19 | Janssen Pharmaceutica N.V. | Mercaptoimidazoles as ccr2 receptor antagonists |
-
2005
- 2005-05-24 MX MXPA06013764A patent/MXPA06013764A/es unknown
- 2005-05-24 AT AT05755042T patent/ATE425161T1/de not_active IP Right Cessation
- 2005-05-24 EA EA200602193A patent/EA200602193A1/ru unknown
- 2005-05-24 BR BRPI0511599-0A patent/BRPI0511599A/pt not_active IP Right Cessation
- 2005-05-24 DE DE602005013216T patent/DE602005013216D1/de not_active Expired - Fee Related
- 2005-05-24 KR KR1020067025786A patent/KR20070020070A/ko not_active Application Discontinuation
- 2005-05-24 US US11/569,268 patent/US20070249691A1/en not_active Abandoned
- 2005-05-24 WO PCT/EP2005/052369 patent/WO2005118578A1/en active Application Filing
- 2005-05-24 CN CNA2005800165554A patent/CN1956980A/zh active Pending
- 2005-05-24 AR ARP050102147A patent/AR049386A1/es not_active Application Discontinuation
- 2005-05-24 AU AU2005250156A patent/AU2005250156A1/en not_active Abandoned
- 2005-05-24 JP JP2007513921A patent/JP2008500310A/ja not_active Withdrawn
- 2005-05-24 EP EP05755042A patent/EP1753758B1/en active Active
- 2005-05-24 CA CA002566187A patent/CA2566187A1/en not_active Abandoned
- 2005-05-25 MY MYPI20052364A patent/MY140571A/en unknown
- 2005-05-25 PA PA20058634401A patent/PA8634401A1/es unknown
- 2005-05-25 TW TW094116985A patent/TW200606154A/zh unknown
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2006
- 2006-11-23 IL IL179518A patent/IL179518A0/en unknown
- 2006-11-24 ZA ZA200609846A patent/ZA200609846B/xx unknown
- 2006-12-27 NO NO20066011A patent/NO20066011L/no not_active Application Discontinuation
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WO2005118578A1 (en) | 2005-12-15 |
MY140571A (en) | 2009-12-31 |
AU2005250156A1 (en) | 2005-12-15 |
BRPI0511599A (pt) | 2008-01-02 |
EA200602193A1 (ru) | 2007-04-27 |
JP2008500310A (ja) | 2008-01-10 |
CA2566187A1 (en) | 2005-12-15 |
CN1956980A (zh) | 2007-05-02 |
ATE425161T1 (de) | 2009-03-15 |
DE602005013216D1 (de) | 2009-04-23 |
MXPA06013764A (es) | 2007-02-08 |
IL179518A0 (en) | 2007-05-15 |
KR20070020070A (ko) | 2007-02-16 |
US20070249691A1 (en) | 2007-10-25 |
EP1753758B1 (en) | 2009-03-11 |
TW200606154A (en) | 2006-02-16 |
EP1753758A1 (en) | 2007-02-21 |
AR049386A1 (es) | 2006-07-26 |
PA8634401A1 (es) | 2006-05-16 |
NO20066011L (no) | 2007-02-23 |
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