ZA200609365B - Monoclonal antibody SC104and derivative therof specifi cally binding to a sialyltetraosyl carbohydrate as a potentia anti-tumor therapeutic agent - Google Patents

Monoclonal antibody SC104and derivative therof specifi cally binding to a sialyltetraosyl carbohydrate as a potentia anti-tumor therapeutic agent

Info

Publication number
ZA200609365B
ZA200609365B ZA200609365A ZA200609365A ZA200609365B ZA 200609365 B ZA200609365 B ZA 200609365B ZA 200609365 A ZA200609365 A ZA 200609365A ZA 200609365 A ZA200609365 A ZA 200609365A ZA 200609365 B ZA200609365 B ZA 200609365B
Authority
ZA
South Africa
Prior art keywords
sc104and
potentia
monoclonal antibody
therapeutic agent
tumor therapeutic
Prior art date
Application number
ZA200609365A
Other languages
English (en)
Inventor
Durrant Linda Gillian
Parsons Tina
Original Assignee
Scancell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32526936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200609365(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scancell Ltd filed Critical Scancell Ltd
Publication of ZA200609365B publication Critical patent/ZA200609365B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3084—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA200609365A 2004-05-12 2006-11-10 Monoclonal antibody SC104and derivative therof specifi cally binding to a sialyltetraosyl carbohydrate as a potentia anti-tumor therapeutic agent ZA200609365B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0410627.4A GB0410627D0 (en) 2004-05-12 2004-05-12 Specific binding members

Publications (1)

Publication Number Publication Date
ZA200609365B true ZA200609365B (en) 2008-05-28

Family

ID=32526936

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200609365A ZA200609365B (en) 2004-05-12 2006-11-10 Monoclonal antibody SC104and derivative therof specifi cally binding to a sialyltetraosyl carbohydrate as a potentia anti-tumor therapeutic agent

Country Status (17)

Country Link
US (2) US7915387B2 (fr)
EP (3) EP2392598A1 (fr)
JP (2) JP4944016B2 (fr)
KR (1) KR101213282B1 (fr)
CN (1) CN1961004B (fr)
AU (2) AU2005240837B2 (fr)
BR (1) BRPI0510950A (fr)
CA (1) CA2563516C (fr)
ES (1) ES2400571T3 (fr)
GB (1) GB0410627D0 (fr)
HK (1) HK1101696A1 (fr)
IL (1) IL178791A (fr)
MX (1) MXPA06012955A (fr)
NO (1) NO20065651L (fr)
NZ (3) NZ589214A (fr)
WO (1) WO2005108430A2 (fr)
ZA (1) ZA200609365B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0410627D0 (en) * 2004-05-12 2004-06-16 Scancell Ltd Specific binding members
BRPI1009460A2 (pt) 2009-03-16 2016-03-01 Cephalon Australia Pty Ltd domínio de ligação do anticorpo, anticorpo, uso de um domínio de ligação ou anticorpo, método para detectar a presença de células cancerígenas em uma amostra.
MX2012005164A (es) 2009-11-05 2012-10-03 Cephalon Australia Pty Ltd Tratamiento de cancer que involucra genes kras o braf mutados.
US9217040B2 (en) 2011-01-14 2015-12-22 The Regents Of The University Of California Therapeutic antibodies against ROR-1 protein and methods for use of same
GB201319374D0 (en) 2013-11-01 2013-12-18 Univ Nottingham Glycans as functional cancer targets abd antibodies thereto
WO2015158851A1 (fr) * 2014-04-16 2015-10-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Anticorps pour la prévention ou le traitement d'épisodes hémorragiques

Family Cites Families (30)

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US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
AU7757581A (en) 1980-11-19 1982-05-27 United Energy Technologies Inc. Enhanced surface tubing
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
JPS5811808A (ja) 1981-07-16 1983-01-22 Niles Parts Co Ltd 方位検出表示回路
EP0088046B1 (fr) 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipides en phase aqueuse
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4630115A (en) 1983-05-09 1986-12-16 The General Electric Company, P.L.C. Cathode ray tube display device
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
EP0143949B1 (fr) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Composition pharmaceutique contenant de l'urokinase
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
DE3920358A1 (de) * 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
SK281142B6 (sk) 1991-03-06 2000-12-11 Merck Patent Gesellschaft Mit Beschr�Nkter Haftung Humanizovaná monoklonálna protilátka, expresné vektory a farmaceutický prostriedok
WO1992019759A1 (fr) 1991-04-25 1992-11-12 Chugai Seiyaku Kabushiki Kaisha Anticorps humains reconstitues diriges contre un recepteur de l'interleukine 6 humaine
DE4118120A1 (de) * 1991-06-03 1992-12-10 Behringwerke Ag Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
US5837242A (en) 1992-12-04 1998-11-17 Medical Research Council Multivalent and multispecific binding proteins, their manufacture and use
DK0699237T3 (da) 1994-03-17 2003-05-26 Merck Patent Gmbh Anti-EGFR enkeltkæde FV'er og anti-EGFR-antistoffer.
JPH09173063A (ja) 1995-12-26 1997-07-08 Cosmo Sogo Kenkyusho:Kk 抗ヒトリポタンパク質（ａ）モノクローナル抗体可変領域のＤＮＡ塩基配列およびアミノ酸配列
US6451995B1 (en) * 1996-03-20 2002-09-17 Sloan-Kettering Institute For Cancer Research Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods
US5994511A (en) * 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
CA2297692A1 (fr) 1997-08-18 1999-02-25 Innogenetics N.V. Molecules de fixation d'interferon-gamma permettant de traiter des chocs septiques, la cachexie, des troubles immunitaires et des problemes dermatologiques
EP1392359B2 (fr) 2001-05-11 2013-03-13 Ludwig Institute for Cancer Research Ltd. Proteines de liaison specifiques et utilisations associees
GB0410627D0 (en) * 2004-05-12 2004-06-16 Scancell Ltd Specific binding members
US9209965B2 (en) 2014-01-14 2015-12-08 Microsemi Semiconductor Ulc Network interface with clock recovery module on line card

Also Published As

Publication number Publication date
NZ593171A (en) 2012-08-31
HK1101696A1 (en) 2007-10-26
NO20065651L (no) 2007-02-06
US7915387B2 (en) 2011-03-29
AU2005240837A1 (en) 2005-11-17
AU2011200487A1 (en) 2011-02-24
JP2012105654A (ja) 2012-06-07
WO2005108430A3 (fr) 2006-04-27
US20080118509A1 (en) 2008-05-22
IL178791A0 (en) 2007-03-08
JP2008502324A (ja) 2008-01-31
BRPI0510950A (pt) 2007-11-20
GB0410627D0 (en) 2004-06-16
EP2397500A1 (fr) 2011-12-21
AU2005240837B2 (en) 2010-11-11
KR20070085116A (ko) 2007-08-27
EP2392598A1 (fr) 2011-12-07
IL178791A (en) 2012-07-31
CA2563516C (fr) 2013-10-01
US8343490B2 (en) 2013-01-01
NZ589214A (en) 2012-02-24
JP4944016B2 (ja) 2012-05-30
EP1745077A2 (fr) 2007-01-24
ES2400571T3 (es) 2013-04-10
EP1745077B1 (fr) 2012-11-28
CN1961004A (zh) 2007-05-09
US20110212113A1 (en) 2011-09-01
KR101213282B1 (ko) 2012-12-17
CA2563516A1 (fr) 2005-11-17
CN1961004B (zh) 2012-11-07
MXPA06012955A (es) 2007-04-25
AU2011200487B2 (en) 2012-11-01
NZ550738A (en) 2011-03-31
WO2005108430A2 (fr) 2005-11-17

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