ZA200605304B - Targeted immunogens - Google Patents
Targeted immunogens Download PDFInfo
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- ZA200605304B ZA200605304B ZA200605304A ZA200605304A ZA200605304B ZA 200605304 B ZA200605304 B ZA 200605304B ZA 200605304 A ZA200605304 A ZA 200605304A ZA 200605304 A ZA200605304 A ZA 200605304A ZA 200605304 B ZA200605304 B ZA 200605304B
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- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical compound OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 description 1
- 125000001446 muramyl group Chemical group N[C@@H](C=O)[C@@H](O[C@@H](C(=O)*)C)[C@H](O)[C@H](O)CO 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000869 mutational effect Effects 0.000 description 1
- 210000000066 myeloid cell Anatomy 0.000 description 1
- AEMBWNDIEFEPTH-UHFFFAOYSA-N n-tert-butyl-n-ethylnitrous amide Chemical compound CCN(N=O)C(C)(C)C AEMBWNDIEFEPTH-UHFFFAOYSA-N 0.000 description 1
- 239000002088 nanocapsule Substances 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000002276 neurotropic effect Effects 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 229940023146 nucleic acid vaccine Drugs 0.000 description 1
- UNEIHNMKASENIG-UHFFFAOYSA-N para-chlorophenylpiperazine Chemical compound C1=CC(Cl)=CC=C1N1CCNCC1 UNEIHNMKASENIG-UHFFFAOYSA-N 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 229940086255 perform Drugs 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 108010021711 pertactin Proteins 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 125000001095 phosphatidyl group Chemical group 0.000 description 1
- 229920002627 poly(phosphazenes) Polymers 0.000 description 1
- 229920001481 poly(stearyl methacrylate) Polymers 0.000 description 1
- 229940115272 polyinosinic:polycytidylic acid Drugs 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 229960000688 pomalidomide Drugs 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009465 prokaryotic expression Effects 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 239000003488 releasing hormone Substances 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 230000003584 silencer Effects 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000002381 testicular Effects 0.000 description 1
- 229960000814 tetanus toxoid Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 229940118696 vibrio cholerae Drugs 0.000 description 1
- 239000000304 virulence factor Substances 0.000 description 1
- 230000007923 virulence factor Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53372803P | 2003-12-31 | 2003-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200605304B true ZA200605304B (en) | 2007-12-27 |
Family
ID=34748948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200605304A ZA200605304B (en) | 2003-12-31 | 2006-06-27 | Targeted immunogens |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20060002946A1 (enExample) |
| EP (1) | EP1699492A2 (enExample) |
| JP (1) | JP2007536911A (enExample) |
| KR (1) | KR20060129353A (enExample) |
| CN (1) | CN1921889A (enExample) |
| AU (1) | AU2004312548A1 (enExample) |
| BR (1) | BRPI0418273A (enExample) |
| CA (1) | CA2552251A1 (enExample) |
| IL (1) | IL176603A0 (enExample) |
| MX (1) | MXPA06007574A (enExample) |
| WO (1) | WO2005066203A2 (enExample) |
| ZA (1) | ZA200605304B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0103110D0 (en) * | 2000-08-25 | 2001-03-28 | Aventis Pharma Inc | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| WO2012123755A1 (en) | 2011-03-17 | 2012-09-20 | The University Of Birmingham | Re-directed immunotherapy |
| KR20170116039A (ko) * | 2015-02-18 | 2017-10-18 | 에프. 호프만-라 로슈 아게 | 표적 세포에 대항하여 t 세포 세포독성을 특이적으로 유도하기 위한 면역컨주게이트 |
| CA2984629C (en) | 2015-05-07 | 2024-06-18 | University Of South Florida | Modified ube3a gene for a gene therapy approach for angelman syndrome |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE391791T1 (de) * | 2000-08-25 | 2008-04-15 | Aventis Pharma Inc | Membran penetrierende peptide und deren anwendungen |
| CA2477429A1 (en) * | 2002-01-29 | 2003-08-07 | Robert A. Uger | Targeted immunogens |
-
2004
- 2004-12-30 AU AU2004312548A patent/AU2004312548A1/en not_active Abandoned
- 2004-12-30 MX MXPA06007574A patent/MXPA06007574A/es unknown
- 2004-12-30 BR BRPI0418273-1A patent/BRPI0418273A/pt not_active IP Right Cessation
- 2004-12-30 US US11/026,403 patent/US20060002946A1/en not_active Abandoned
- 2004-12-30 WO PCT/US2004/044023 patent/WO2005066203A2/en not_active Ceased
- 2004-12-30 CA CA002552251A patent/CA2552251A1/en not_active Abandoned
- 2004-12-30 CN CNA2004800421537A patent/CN1921889A/zh active Pending
- 2004-12-30 JP JP2006547589A patent/JP2007536911A/ja not_active Abandoned
- 2004-12-30 KR KR1020067015438A patent/KR20060129353A/ko not_active Withdrawn
- 2004-12-30 EP EP04816007A patent/EP1699492A2/en not_active Withdrawn
-
2006
- 2006-06-27 ZA ZA200605304A patent/ZA200605304B/en unknown
- 2006-06-28 IL IL176603A patent/IL176603A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005066203A2 (en) | 2005-07-21 |
| IL176603A0 (en) | 2006-10-31 |
| US20060002946A1 (en) | 2006-01-05 |
| CN1921889A (zh) | 2007-02-28 |
| WO2005066203A3 (en) | 2005-09-01 |
| JP2007536911A (ja) | 2007-12-20 |
| BRPI0418273A (pt) | 2007-05-02 |
| EP1699492A2 (en) | 2006-09-13 |
| MXPA06007574A (es) | 2007-04-17 |
| KR20060129353A (ko) | 2006-12-15 |
| AU2004312548A1 (en) | 2005-07-21 |
| CA2552251A1 (en) | 2005-07-21 |
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