ZA200600184B - Cancer combination therapy comprising AZD 2171 and ZD 1839 - Google Patents

Cancer combination therapy comprising AZD 2171 and ZD 1839 Download PDF

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Publication number
ZA200600184B
ZA200600184B ZA200600184A ZA200600184A ZA200600184B ZA 200600184 B ZA200600184 B ZA 200600184B ZA 200600184 A ZA200600184 A ZA 200600184A ZA 200600184 A ZA200600184 A ZA 200600184A ZA 200600184 B ZA200600184 B ZA 200600184B
Authority
ZA
South Africa
Prior art keywords
pharmaceutically acceptable
acceptable salt
azd2171
human
warm
Prior art date
Application number
ZA200600184A
Other languages
English (en)
Inventor
Wedge Stephen Robert
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200600184B publication Critical patent/ZA200600184B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
ZA200600184A 2003-07-10 2006-01-09 Cancer combination therapy comprising AZD 2171 and ZD 1839 ZA200600184B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0316127.0A GB0316127D0 (en) 2003-07-10 2003-07-10 Combination therapy

Publications (1)

Publication Number Publication Date
ZA200600184B true ZA200600184B (en) 2007-04-25

Family

ID=27741907

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200600184A ZA200600184B (en) 2003-07-10 2006-01-09 Cancer combination therapy comprising AZD 2171 and ZD 1839

Country Status (24)

Country Link
US (2) US20060167024A1 (no)
EP (1) EP1653964B1 (no)
JP (1) JP2007526888A (no)
KR (1) KR20060033785A (no)
CN (1) CN100415236C (no)
AT (1) ATE409039T1 (no)
AU (1) AU2004255024B2 (no)
BR (1) BRPI0412408A (no)
CA (1) CA2531620C (no)
DE (1) DE602004016754D1 (no)
DK (1) DK1653964T3 (no)
ES (1) ES2313033T3 (no)
GB (1) GB0316127D0 (no)
HK (1) HK1089667A1 (no)
HR (1) HRP20080597T3 (no)
IL (1) IL172683A0 (no)
MX (1) MXPA06000412A (no)
NO (1) NO20056170L (no)
NZ (1) NZ544270A (no)
PL (1) PL1653964T3 (no)
PT (1) PT1653964E (no)
SI (1) SI1653964T1 (no)
WO (1) WO2005004872A1 (no)
ZA (1) ZA200600184B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
GB0218526D0 (en) * 2002-08-09 2002-09-18 Astrazeneca Ab Combination therapy
GB0310401D0 (en) * 2003-05-07 2003-06-11 Astrazeneca Ab Therapeutic agent
NZ549552A (en) * 2004-03-23 2009-12-24 Astrazeneca Ab Combination therapy involving 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline (AZD2171) and a platinum anti-tumour agent
GB0406445D0 (en) * 2004-03-23 2004-04-28 Astrazeneca Ab Combination therapy
EP1901754A2 (en) * 2005-07-06 2008-03-26 AstraZeneca AB Combination therapy of cancer with azd2171 and gemcitabine
US20080306094A1 (en) * 2005-12-22 2008-12-11 Stephen Robert Wedge Combination of Azd2171 and Pemetrexed
WO2009118560A1 (en) * 2008-03-28 2009-10-01 Astrazeneca Ab Combination therapy 038
EP2113255A1 (en) * 2008-05-02 2009-11-04 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Cytotoxic immunoglobulin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU762615B2 (en) * 1998-06-15 2003-07-03 Arch Development Corporation Combination of radiotherapy and anti-angiogenic factors
AU763618B2 (en) * 1999-02-10 2003-07-31 Astrazeneca Ab Quinazoline derivatives as angiogenesis inhibitors
NZ534190A (en) * 2000-03-31 2007-05-31 Angiogene Pharm Ltd Divided dose therapies with vascular damaging activity
GB0008269D0 (en) * 2000-04-05 2000-05-24 Astrazeneca Ab Combination chemotherapy
AU2002223684A1 (en) * 2000-11-22 2002-06-03 Novartis Pharma Gmbh Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity
RU2365588C2 (ru) * 2002-02-01 2009-08-27 Астразенека Аб Хиназолиновые соединения

Also Published As

Publication number Publication date
DK1653964T3 (da) 2009-01-05
EP1653964A1 (en) 2006-05-10
CN1819831A (zh) 2006-08-16
PL1653964T3 (pl) 2009-01-30
PT1653964E (pt) 2008-11-24
WO2005004872A1 (en) 2005-01-20
GB0316127D0 (en) 2003-08-13
US20060167024A1 (en) 2006-07-27
CN100415236C (zh) 2008-09-03
EP1653964B1 (en) 2008-09-24
AU2004255024B2 (en) 2007-09-27
ES2313033T3 (es) 2009-03-01
BRPI0412408A (pt) 2006-08-22
HK1089667A1 (en) 2006-12-08
KR20060033785A (ko) 2006-04-19
IL172683A0 (en) 2006-04-10
NO20056170L (no) 2006-02-08
CA2531620C (en) 2011-09-27
MXPA06000412A (es) 2006-03-17
SI1653964T1 (sl) 2009-02-28
NZ544270A (en) 2007-09-28
HRP20080597T3 (en) 2008-12-31
ATE409039T1 (de) 2008-10-15
CA2531620A1 (en) 2005-01-20
US20100179142A1 (en) 2010-07-15
AU2004255024A1 (en) 2005-01-20
JP2007526888A (ja) 2007-09-20
DE602004016754D1 (de) 2008-11-06

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