ZA200509663B - Tropane derivatives and their use as ACE inhibitors - Google Patents
Tropane derivatives and their use as ACE inhibitors Download PDFInfo
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- ZA200509663B ZA200509663B ZA200509663A ZA200509663A ZA200509663B ZA 200509663 B ZA200509663 B ZA 200509663B ZA 200509663 A ZA200509663 A ZA 200509663A ZA 200509663 A ZA200509663 A ZA 200509663A ZA 200509663 B ZA200509663 B ZA 200509663B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP0304490 | 2003-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200509663B true ZA200509663B (en) | 2006-09-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200509663A ZA200509663B (en) | 2003-04-30 | 2005-11-29 | Tropane derivatives and their use as ACE inhibitors |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060205768A1 (ru) |
| EP (1) | EP1622901A1 (ru) |
| JP (1) | JP2006524657A (ru) |
| KR (1) | KR20060015546A (ru) |
| CN (1) | CN1780833A (ru) |
| AU (1) | AU2004234042A1 (ru) |
| BR (1) | BRPI0409878A (ru) |
| CA (1) | CA2521957A1 (ru) |
| MX (1) | MXPA05011497A (ru) |
| NO (1) | NO20055624L (ru) |
| RU (1) | RU2005137184A (ru) |
| WO (1) | WO2004096799A1 (ru) |
| ZA (1) | ZA200509663B (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1680427A1 (en) * | 2003-10-23 | 2006-07-19 | Actelion Pharmaceuticals Ltd. | Diazabicyclononene and tetrahydropyridine derivatives as renin inhibitors |
| WO2005054244A2 (en) * | 2003-12-05 | 2005-06-16 | Actelion Pharmaceuticals Ltd | Azabicyclooctene and other tetrahydropyridine derivatives with a new side-chain |
| US8138340B2 (en) | 2004-08-25 | 2012-03-20 | Actelion Pharmaceuticals Ltd. | Bicyclononene derivatives |
| GB0428526D0 (en) | 2004-12-30 | 2005-02-09 | Novartis Ag | Organic compounds |
| WO2006092268A1 (en) * | 2005-03-02 | 2006-09-08 | Actelion Pharmaceuticals Ltd | Bicyclic five-membered heteroaryl derivatives and their use as renin inhibitors |
| GB0514203D0 (en) | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
| WO2007049224A1 (en) * | 2005-10-25 | 2007-05-03 | Actelion Pharmaceuticals Ltd | Novel hexahydro- or octahydro-cyclopenta[c]pyrrole derivatives |
| ES2430139T3 (es) | 2005-12-30 | 2013-11-19 | Novartis Ag | Compuestos de piperidina 3,5-sustituido como inhibidores de renina |
| WO2007088514A1 (en) | 2006-02-02 | 2007-08-09 | Actelion Pharmaceuticals Ltd | Secondary amines as renin inhibitors |
| WO2007104652A2 (en) * | 2006-03-16 | 2007-09-20 | Nicox S.A. | Non-peptidic renin inhibitors nitroderivatives |
| JP2010527942A (ja) | 2007-05-24 | 2010-08-19 | メルク フロスト カナダ リミテツド | 新規類のレニン阻害剤 |
| ES2541107T3 (es) | 2007-06-25 | 2015-07-16 | Novartis Ag | Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidindicarboxamida para su uso como inhibidores de renina |
| WO2009023964A1 (en) | 2007-08-20 | 2009-02-26 | Merck Frosst Canada Ltd. | Renin inhibitors |
| WO2009135299A1 (en) | 2008-05-05 | 2009-11-12 | Merck Frosst Canada Ltd. | 3, 4 - substituted piperidine derivatives as renin inhibitors |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3509161A (en) * | 1967-07-10 | 1970-04-28 | Boehringer & Soehne Gmbh | 3-phenyl-granatene-(2)-derivatives |
| US7011813B2 (en) * | 1990-08-09 | 2006-03-14 | Research Triangle Institute | Cocaine receptor binding ligands |
| US6329520B1 (en) * | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
| US5380758A (en) * | 1991-03-29 | 1995-01-10 | Brigham And Women's Hospital | S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof |
| PL294866A1 (en) * | 1991-06-21 | 1993-05-31 | Hoechst Ag | Method of obtaining novel rennin redtarding heterocyclic compounds |
| US5703073A (en) * | 1995-04-19 | 1997-12-30 | Nitromed, Inc. | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs |
| NZ315677A (en) * | 1995-09-07 | 2000-02-28 | F | 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiency |
| US20030013883A1 (en) * | 2000-06-16 | 2003-01-16 | Tamagnan Gilles D. | Tropane analogs binding to monoamine transporters |
| WO2002076440A2 (en) * | 2001-03-23 | 2002-10-03 | Elan Pharmaceuticals, Inc. | Methods of treating alzheimer's disease with piperidin derivates |
| CA2483241C (en) * | 2002-04-29 | 2011-05-31 | Actelion Pharmaceuticals Ltd | Novel diazabicyclononene derivatives |
-
2004
- 2004-04-26 US US10/554,704 patent/US20060205768A1/en not_active Abandoned
- 2004-04-26 EP EP04729423A patent/EP1622901A1/en not_active Withdrawn
- 2004-04-26 KR KR1020057020498A patent/KR20060015546A/ko not_active Application Discontinuation
- 2004-04-26 RU RU2005137184/04A patent/RU2005137184A/ru not_active Application Discontinuation
- 2004-04-26 CA CA002521957A patent/CA2521957A1/en not_active Abandoned
- 2004-04-26 CN CNA2004800114420A patent/CN1780833A/zh active Pending
- 2004-04-26 JP JP2006505264A patent/JP2006524657A/ja active Pending
- 2004-04-26 BR BRPI0409878-1A patent/BRPI0409878A/pt not_active Application Discontinuation
- 2004-04-26 MX MXPA05011497A patent/MXPA05011497A/es not_active Application Discontinuation
- 2004-04-26 AU AU2004234042A patent/AU2004234042A1/en not_active Abandoned
- 2004-04-26 WO PCT/EP2004/004375 patent/WO2004096799A1/en not_active Application Discontinuation
-
2005
- 2005-11-29 NO NO20055624A patent/NO20055624L/no not_active Application Discontinuation
- 2005-11-29 ZA ZA200509663A patent/ZA200509663B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006524657A (ja) | 2006-11-02 |
| CN1780833A (zh) | 2006-05-31 |
| KR20060015546A (ko) | 2006-02-17 |
| MXPA05011497A (es) | 2005-12-15 |
| BRPI0409878A (pt) | 2006-05-23 |
| WO2004096799A1 (en) | 2004-11-11 |
| RU2005137184A (ru) | 2006-03-20 |
| EP1622901A1 (en) | 2006-02-08 |
| CA2521957A1 (en) | 2004-11-11 |
| AU2004234042A1 (en) | 2004-11-11 |
| US20060205768A1 (en) | 2006-09-14 |
| NO20055624L (no) | 2005-11-29 |
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