ZA200500926B - Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors - Google Patents

Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors

Info

Publication number
ZA200500926B
ZA200500926B ZA200500926A ZA200500926A ZA200500926B ZA 200500926 B ZA200500926 B ZA 200500926B ZA 200500926 A ZA200500926 A ZA 200500926A ZA 200500926 A ZA200500926 A ZA 200500926A ZA 200500926 B ZA200500926 B ZA 200500926B
Authority
ZA
South Africa
Prior art keywords
broadspectrum
amino
protease inhibitors
hiv protease
benzothiazole sulfonamide
Prior art date
Application number
ZA200500926A
Other languages
English (en)
Inventor
Dominique L N G Suleraux
Daniel P Getman
Piet T B P Wigerinck
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of ZA200500926B publication Critical patent/ZA200500926B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
ZA200500926A 2002-08-02 2006-01-16 Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors ZA200500926B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02078231 2002-08-02

Publications (1)

Publication Number Publication Date
ZA200500926B true ZA200500926B (en) 2006-03-29

Family

ID=38068099

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500926A ZA200500926B (en) 2002-08-02 2006-01-16 Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors

Country Status (5)

Country Link
JP (1) JP4879484B2 (xx)
KR (1) KR101327772B1 (xx)
CN (1) CN101445493A (xx)
OA (1) OA12893A (xx)
ZA (1) ZA200500926B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA103013C2 (uk) * 2007-12-06 2013-09-10 Тиботек Фармасьютикелз Амідні сполуки як активатори противірусних препаратів
MX2013012266A (es) * 2011-04-21 2013-11-22 Gilead Sciences Inc Compuestos de benzotiazol y su uso farmaceutico.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2127938T3 (es) * 1993-08-24 1999-05-01 Searle & Co Hidroxietilamino sulfonamidas utiles como inhibidores de proteasas retroviricas.
US5756533A (en) * 1995-03-10 1998-05-26 G.D. Searle & Co. Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
AU7722296A (en) * 1995-11-15 1997-06-05 G.D. Searle & Co. Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
AU4828199A (en) * 1998-06-23 2000-01-10 Board Of Trustees Of The University Of Illinois, The Multi-drug resistant retroviral protease inhibitors and associated methods
CZ300031B6 (cs) * 1999-10-06 2009-01-14 Tibotec Pharmaceuticals Ltd. Hexahydrofuro[2,3-b]furan-3-yl-N-{3-[(1,3-benzodioxol-5-ylsulfonyl) (isobutyl)amino]-1-benzyl-2-hydroxypropyl}karbamát a farmaceutický prípravek s jeho obsahem
ES2275866T3 (es) * 2001-02-14 2007-06-16 Tibotec Pharmaceuticals Ltd. 2-(aminosustituido)-benzotiazol-sulfonamidas de amplio esprecto inhibidoras de la proteasa de vih.

Also Published As

Publication number Publication date
KR20100137584A (ko) 2010-12-30
OA12893A (en) 2006-10-13
JP2006503815A (ja) 2006-02-02
KR101327772B1 (ko) 2013-11-11
CN101445493A (zh) 2009-06-03
JP4879484B2 (ja) 2012-02-22

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