ZA200409401B - Method for producing steroid crystals, crystals obtained by said method and their use in pharmaceutical formulations. - Google Patents

Method for producing steroid crystals, crystals obtained by said method and their use in pharmaceutical formulations.

Info

Publication number
ZA200409401B
ZA200409401B ZA200409401A ZA200409401A ZA200409401B ZA 200409401 B ZA200409401 B ZA 200409401B ZA 200409401 A ZA200409401 A ZA 200409401A ZA 200409401 A ZA200409401 A ZA 200409401A ZA 200409401 B ZA200409401 B ZA 200409401B
Authority
ZA
South Africa
Prior art keywords
crystals
mum
pharmaceutical formulations
steroid
crystals obtained
Prior art date
Application number
ZA200409401A
Other languages
English (en)
Inventor
Detlef Grawe
Peter Hoesel
Sabine Gliesing
Hagen Gerecke
Annette Eichardt
Uwe Mueller
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA200409401B publication Critical patent/ZA200409401B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA200409401A 2002-04-23 2004-11-22 Method for producing steroid crystals, crystals obtained by said method and their use in pharmaceutical formulations. ZA200409401B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10218107A DE10218107A1 (de) 2002-04-23 2002-04-23 Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen

Publications (1)

Publication Number Publication Date
ZA200409401B true ZA200409401B (en) 2006-02-22

Family

ID=29264787

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200409401A ZA200409401B (en) 2002-04-23 2004-11-22 Method for producing steroid crystals, crystals obtained by said method and their use in pharmaceutical formulations.

Country Status (20)

Country Link
US (1) US7148212B2 (ko)
EP (1) EP1497308B1 (ko)
JP (1) JP4490116B2 (ko)
KR (1) KR20040106380A (ko)
CN (1) CN1646555A (ko)
AT (1) ATE340186T1 (ko)
AU (1) AU2003232491A1 (ko)
BR (1) BR0309357A (ko)
CA (1) CA2480004C (ko)
DE (2) DE10218107A1 (ko)
DK (1) DK1497308T3 (ko)
ES (1) ES2274258T3 (ko)
IL (1) IL163986A0 (ko)
MX (1) MXPA04010467A (ko)
NO (1) NO20045023L (ko)
PL (1) PL371340A1 (ko)
PT (1) PT1497308E (ko)
RU (1) RU2315056C2 (ko)
WO (1) WO2003091272A1 (ko)
ZA (1) ZA200409401B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10218109A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
US20080038350A1 (en) * 2006-08-10 2008-02-14 Hagen Gerecke Low-dosage peroral medication for contraception containing crystalline dienogest and ethinyl estradiol
EP1886694B1 (de) * 2006-08-10 2009-06-03 Bayer Schering Pharma Aktiengesellschaft Perorale Arzneiform mit Dienogest und Ethinylestradiol zur Kontrazeption
DE102008037025C5 (de) 2008-08-08 2016-07-07 Jesalis Pharma Gmbh Verfahren zur Herstellung kristalliner Wirkstoff-Mikropartikel bzw. einer Wirkstoffpartikel-Festkörperform
DE102010003711B4 (de) 2010-04-08 2015-04-09 Jesalis Pharma Gmbh Verfahren zur Herstellung kristalliner Wirkstoffpartikel
RU2642244C2 (ru) * 2010-04-12 2018-01-24 Кларус Терапеутикс, Инк. Оральные фармацевтические композиции сложных эфиров тестостерона и способы лечения недостатка тестостерона с их использованием
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
JP6426758B2 (ja) 2014-05-13 2018-11-21 アクゾ ノーベル ケミカルズ インターナショナル ベスローテン フエンノートシャップＡｋｚｏ Ｎｏｂｅｌ Ｃｈｅｍｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｂ．Ｖ． キレート剤を結晶化するプロセス
EP3544614A4 (en) 2016-11-28 2020-08-05 Lipocine Inc. ORAL TESTOSTERONE UNDECANOATE THERAPY
WO2021230308A1 (ja) 2020-05-15 2021-11-18 塩野義製薬株式会社 不純物の生成を抑制した医薬組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3226389A (en) 1962-01-04 1965-12-28 Du Pont 11,11,12,12-tetracyano-naphtho-2,6-quinodimethan and its anion-radical salts
HU209603B (en) 1988-10-05 1994-09-28 Upjohn Co Process for production of solid powders in finalydivided microcristallin form
DE3917617A1 (de) 1989-05-31 1990-12-06 Boehringer Ingelheim Kg Mikronisierte bioabbaubare partikel, verfahren zur ihrer herstellung und ihre verwendung
FR2668945B1 (fr) 1990-11-12 1993-02-19 Theramex Nouveau procede de cristallisation des substances organiques et les composes ainsi obtenus.
EP0522700B1 (en) 1991-07-10 1997-01-29 Chiyoda Corporation Process for the production of crystalline adduct of bisphenol A and phenol and apparatus therefor
NZ248813A (en) * 1992-11-25 1995-06-27 Eastman Kodak Co Polymeric grinding media used in grinding pharmaceutical substances
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5609672A (en) * 1993-12-27 1997-03-11 Nippon Soda Co., Ltd. Composition for color development comprising 4-hydroxy-4'-isopropoxydiphenylsulfone, and a wet method for grinding and a dispersible solution for applying the same
US5718388A (en) * 1994-05-25 1998-02-17 Eastman Kodak Continuous method of grinding pharmaceutical substances
US5534270A (en) * 1995-02-09 1996-07-09 Nanosystems Llc Method of preparing stable drug nanoparticles
EP1142866A4 (en) * 1998-12-25 2003-05-28 Daiichi Fine Chem Co Ltd METHOD FOR PURIFYING CALCIUM PANTOTHENATE
EP1157996A1 (de) * 2000-05-23 2001-11-28 JENAPHARM GmbH Neue Festkörperformen des Mesoprogestins 11Beta-[4E-(Hydroxyiminomethyl)-phenyl]-17Alpha-methoxymethyl-17Beta-methoxy-estra-4,9-dien-3-on
DE10218109A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen

Also Published As

Publication number Publication date
PL371340A1 (en) 2005-06-13
CA2480004A1 (en) 2003-11-06
DE10218107A1 (de) 2003-11-20
DE50305122D1 (de) 2006-11-02
NO20045023L (no) 2004-11-18
IL163986A0 (en) 2005-12-18
EP1497308A1 (de) 2005-01-19
ES2274258T3 (es) 2007-05-16
WO2003091272A1 (de) 2003-11-06
RU2004134324A (ru) 2006-02-10
US7148212B2 (en) 2006-12-12
EP1497308B1 (de) 2006-09-20
US20030216360A1 (en) 2003-11-20
MXPA04010467A (es) 2004-12-13
ATE340186T1 (de) 2006-10-15
RU2315056C2 (ru) 2008-01-20
PT1497308E (pt) 2007-01-31
CA2480004C (en) 2007-11-13
AU2003232491A1 (en) 2003-11-10
JP2005524698A (ja) 2005-08-18
BR0309357A (pt) 2005-02-22
JP4490116B2 (ja) 2010-06-23
KR20040106380A (ko) 2004-12-17
CN1646555A (zh) 2005-07-27
DK1497308T3 (da) 2007-01-29

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