ZA200402794B - Organ preservation apparatus and methods. - Google Patents
Organ preservation apparatus and methods. Download PDFInfo
- Publication number
- ZA200402794B ZA200402794B ZA200402794A ZA200402794A ZA200402794B ZA 200402794 B ZA200402794 B ZA 200402794B ZA 200402794 A ZA200402794 A ZA 200402794A ZA 200402794 A ZA200402794 A ZA 200402794A ZA 200402794 B ZA200402794 B ZA 200402794B
- Authority
- ZA
- South Africa
- Prior art keywords
- organ
- perfusion fluid
- perfusion
- fluid
- oxygen
- Prior art date
Links
- 239000000082 organ preservation Substances 0.000 title abstract description 4
- 238000000034 method Methods 0.000 title description 5
- 210000000056 organ Anatomy 0.000 claims abstract description 90
- 239000012530 fluid Substances 0.000 claims abstract description 52
- 230000010412 perfusion Effects 0.000 claims abstract description 43
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 32
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 32
- 239000001301 oxygen Substances 0.000 claims abstract description 32
- 239000007789 gas Substances 0.000 claims description 15
- 238000002054 transplantation Methods 0.000 claims description 10
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 6
- 239000001569 carbon dioxide Substances 0.000 claims description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 3
- 230000002572 peristaltic effect Effects 0.000 claims description 2
- 238000012546 transfer Methods 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 abstract description 7
- 230000002792 vascular Effects 0.000 abstract description 4
- 239000002826 coolant Substances 0.000 abstract description 3
- 238000003860 storage Methods 0.000 abstract description 3
- 238000002513 implantation Methods 0.000 abstract description 2
- 210000002216 heart Anatomy 0.000 description 21
- 239000012528 membrane Substances 0.000 description 14
- 238000001356 surgical procedure Methods 0.000 description 8
- 230000008901 benefit Effects 0.000 description 5
- 210000000709 aorta Anatomy 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000006213 oxygenation reaction Methods 0.000 description 4
- 239000012266 salt solution Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 230000004083 survival effect Effects 0.000 description 4
- 230000035899 viability Effects 0.000 description 4
- 238000001816 cooling Methods 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 230000004962 physiological condition Effects 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
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- 230000009977 dual effect Effects 0.000 description 2
- 230000002631 hypothermal effect Effects 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 229920000260 silastic Polymers 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
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- 208000007204 Brain death Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 208000005176 Hepatitis C Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
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- 239000007864 aqueous solution Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 239000008366 buffered solution Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000002960 lipid emulsion Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001706 oxygenating effect Effects 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920005668 polycarbonate resin Polymers 0.000 description 1
- 239000004431 polycarbonate resin Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000000541 pulsatile effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
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- 230000001256 tonic effect Effects 0.000 description 1
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- 239000003053 toxin Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0273—Transport containers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/953,338 US6677150B2 (en) | 2001-09-14 | 2001-09-14 | Organ preservation apparatus and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200402794B true ZA200402794B (en) | 2004-10-25 |
Family
ID=25493839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200402794A ZA200402794B (en) | 2001-09-14 | 2004-04-13 | Organ preservation apparatus and methods. |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6677150B2 (es) |
| EP (1) | EP1435777B1 (es) |
| AT (1) | ATE469548T1 (es) |
| DE (1) | DE60236607D1 (es) |
| ES (1) | ES2348466T3 (es) |
| WO (1) | WO2003024214A1 (es) |
| ZA (1) | ZA200402794B (es) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
| NL1013524C2 (nl) * | 1999-11-08 | 2001-05-09 | Univ Amsterdam | Inrichting voor machinale orgaanperfusie gedurende de transportfase van een donororgaan. |
| US6677150B2 (en) * | 2001-09-14 | 2004-01-13 | Organ Transport Systems, Inc. | Organ preservation apparatus and methods |
| US20040170950A1 (en) * | 2002-09-12 | 2004-09-02 | Prien Samuel D. | Organ preservation apparatus and methods |
| AU2003272629A1 (en) * | 2002-09-18 | 2004-04-08 | Lifeblood Medical Inc. | Organ preservation and transportation apparatus and method |
| CA2521427C (en) * | 2003-04-04 | 2012-11-20 | Organ Recovery Systems, Inc. | Device for separating gas from a liquid path |
| US7691622B2 (en) * | 2003-04-04 | 2010-04-06 | Lifeline Scientific, Inc. | Method and apparatus for transferring heat to or from an organ or tissue container |
| NL1024022C2 (nl) * | 2003-07-30 | 2005-02-01 | Technologiestichting Stw | Draagbare preservatie-inrichting voor een donororgaan. |
| US20050153271A1 (en) * | 2004-01-13 | 2005-07-14 | Wenrich Marshall S. | Organ preservation apparatus and methods |
| US9301519B2 (en) * | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| CA3178010A1 (en) * | 2004-10-07 | 2006-04-20 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
| US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US20060147429A1 (en) * | 2004-12-30 | 2006-07-06 | Paul Diamond | Facilitated cellular reconstitution of organs and tissues |
| US20060148080A1 (en) * | 2004-12-30 | 2006-07-06 | Paul Diamond | Methods for supporting and producing human cells and tissues in non-human mammal hosts |
| US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| CA2980782C (en) * | 2006-04-19 | 2020-10-27 | Transmedics, Inc. | Systems and methods for ex vivo organ care |
| US20080145919A1 (en) * | 2006-12-18 | 2008-06-19 | Franklin Thomas D | Portable organ and tissue preservation apparatus, kit and methods |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| WO2009023626A1 (en) * | 2007-08-10 | 2009-02-19 | The Trustees Of Columbia University In The City Of New York | Systems and methods for tissue characterization and border detection |
| EP2203046B1 (en) * | 2007-09-28 | 2015-05-27 | Organ Assist B.V. | Organ transport container system |
| US10750738B2 (en) * | 2008-01-31 | 2020-08-25 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| US10091985B2 (en) * | 2009-06-18 | 2018-10-09 | Giner, Inc. | Perfusing an organ with an in situ generated gas |
| US9357764B2 (en) | 2009-06-18 | 2016-06-07 | Giner, Inc. | System for fluid perfusion of biological matter comprising tissue |
| US9320269B2 (en) | 2009-09-25 | 2016-04-26 | John Brassil | Organ preservation system |
| US8297070B2 (en) * | 2010-02-16 | 2012-10-30 | Pryor Greg L | Race car cooler |
| US9060507B2 (en) | 2010-09-01 | 2015-06-23 | Perfusion Fluid Technologies Inc | Perfusion solution |
| US12082575B2 (en) | 2010-09-01 | 2024-09-10 | Organ Transport Pty Ltd | Perfusion solution |
| US9426979B2 (en) | 2011-03-15 | 2016-08-30 | Paragonix Technologies, Inc. | Apparatus for oxygenation and perfusion of tissue for organ preservation |
| US9253976B2 (en) | 2011-03-15 | 2016-02-09 | Paragonix Technologies, Inc. | Methods and devices for preserving tissues |
| US8828710B2 (en) | 2011-03-15 | 2014-09-09 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
| US20210392873A1 (en) | 2011-03-15 | 2021-12-23 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
| US9867368B2 (en) | 2011-03-15 | 2018-01-16 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
| EP2685814B1 (en) | 2011-03-15 | 2016-08-17 | Paragonix Technologies, Inc. | Apparatus for oxygenation and perfusion of tissue for organ preservation |
| US12096765B1 (en) | 2011-03-15 | 2024-09-24 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
| US11178866B2 (en) | 2011-03-15 | 2021-11-23 | Paragonix Technologies, Inc. | System for hypothermic transport of samples |
| CN103841824B (zh) | 2011-04-14 | 2016-12-14 | 特兰斯迈迪茨公司 | 用于供体肺的离体机器灌注的器官护理溶液 |
| US9756848B2 (en) | 2011-09-02 | 2017-09-12 | Organ Assist B.V. | Apparatus, system and method for conditioning and preserving an organ from a donor |
| US20140017665A1 (en) | 2012-07-10 | 2014-01-16 | Lifeline Scientific, Inc. | Organ transporter with oxygen generation |
| US8785116B2 (en) | 2012-08-10 | 2014-07-22 | Paragonix Technologies, Inc. | Methods for evaluating the suitability of an organ for transplant |
| US9560846B2 (en) | 2012-08-10 | 2017-02-07 | Paragonix Technologies, Inc. | System for hypothermic transport of biological samples |
| CA2924681C (en) | 2013-09-24 | 2019-12-31 | Giner, Inc. | System for gas treatment of a cell implant |
| IL303658B2 (en) | 2014-06-02 | 2024-07-01 | Transmedics Inc | Extracorporeal system for organ treatment |
| USD765874S1 (en) | 2014-10-10 | 2016-09-06 | Paragonix Technologies, Inc. | Transporter for a tissue transport system |
| CA2970117A1 (en) | 2014-12-12 | 2016-06-16 | Darren FREED | Apparatus and method for organ perfusion |
| CN104886037B (zh) * | 2015-05-06 | 2017-01-18 | 中南大学 | 一种生物样本模拟保存实验装置及保存生物样本的方法 |
| ES2853027T3 (es) | 2015-09-09 | 2021-09-14 | Transmedics Inc | Cánula aórtica para sistema de cuidado de órganos ex vivo |
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| US10091986B2 (en) * | 2016-05-09 | 2018-10-09 | Xor-Labs Toronto Inc. | Organ perfusion device and method |
| EP3462861B9 (en) | 2016-05-30 | 2023-12-20 | Transmedics, Inc. | Method for ex vivo lung ventilation with a varying exterior pressure |
| MX2019005674A (es) | 2016-11-15 | 2019-09-09 | Giner Life Sciences Inc | Generador de gas electrolitico auto-regulado y sistema de implante que comprende el mismo. |
| KR20190086489A (ko) | 2016-11-15 | 2019-07-22 | 기너 라이프 사이언시즈, 인크. | 피하 임플란트와 함께 이용하기에 적합한 경피 가스 확산 장치 |
| EP3634127A4 (en) | 2017-06-07 | 2021-03-17 | Paragonix Technologies Inc. | APPARATUS FOR TRANSPORTING AND PRESERVING FABRIC |
| JP7240832B2 (ja) * | 2017-08-29 | 2023-03-16 | 株式会社Ｓｃｒｅｅｎホールディングス | 臓器保存容器および灌流装置 |
| JP7351860B2 (ja) * | 2018-02-26 | 2023-09-27 | ヘモベント ゲーエムベーハー | 酸素付加器及び血液ポンプを保持するための保持装置 |
| CN112384267B (zh) | 2018-05-17 | 2022-08-09 | 吉纳生命科学公司 | 具有组合的引线和气体端口端子的电解气体发生器 |
| WO2020252148A1 (en) * | 2019-06-11 | 2020-12-17 | Paragonix Technologies, Inc. | Organ transport container with antiviral therapy |
| WO2021036738A1 (zh) * | 2019-08-26 | 2021-03-04 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | 离体器官灌注容器 |
| US11632951B2 (en) | 2020-01-31 | 2023-04-25 | Paragonix Technologies, Inc. | Apparatus for tissue transport and preservation |
| CN113016784A (zh) * | 2021-03-22 | 2021-06-25 | 上海长征医院 | 一种离体断肢机械灌注保存箱 |
| USD1031028S1 (en) | 2022-09-08 | 2024-06-11 | Paragonix Technologies, Inc. | Tissue suspension adaptor |
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| US3772153A (en) * | 1969-04-02 | 1973-11-13 | Air Liquide | Apparatus for the preservation of animal or human organs in living condition |
| US3810367A (en) | 1970-07-16 | 1974-05-14 | W Peterson | Container for cooling, storage, and shipping of human organ for transplant |
| DE2241698C2 (de) | 1971-09-02 | 1982-08-26 | Roland Dr.med. Zürich Doerig | Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens |
| US3777507A (en) * | 1971-11-24 | 1973-12-11 | Waters Instr Inc | Renal preservation system |
| US3881990A (en) | 1971-11-24 | 1975-05-06 | Waters Instr Inc | Method of transporting and storing organs while retaining the organs in a viable condition |
| US3995444A (en) | 1974-11-08 | 1976-12-07 | American Hospital Supply Corporation | Organ perfusion system |
| US4186565A (en) | 1978-05-19 | 1980-02-05 | Henry Ford Hospital | Perfusion system for organ preservation |
| US5051352A (en) | 1987-10-07 | 1991-09-24 | The Regents Of The University Of California | Apparatus and method of preserving the viability of animal organs |
| US5326706A (en) | 1989-07-17 | 1994-07-05 | Research Foundation Of State University Of New York | Homeostatic organ preservation system |
| FR2667297B1 (fr) | 1990-09-28 | 1994-05-27 | Electrolux Sarl | Conteneur medical climatise. |
| US5157930A (en) | 1991-04-22 | 1992-10-27 | Mcghee Samuel C | Organ preservation apparatus |
| US5217860A (en) | 1991-07-08 | 1993-06-08 | The American National Red Cross | Method for preserving organs for transplantation by vitrification |
| US5856081A (en) | 1991-07-08 | 1999-01-05 | The American National Red Cross | Computer controlled cryoprotectant perfusion apparatus |
| US5356771A (en) | 1993-03-11 | 1994-10-18 | Board Of Regents, The University Of Texas System | Combined perfusion and oxygenation organ preservation apparatus |
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| JP3603355B2 (ja) * | 1994-12-19 | 2004-12-22 | ニプロ株式会社 | 臓器保存装置用酸素付加装置 |
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| US6794182B2 (en) * | 2000-03-13 | 2004-09-21 | E. George Wolf, Jr. | Hyperbaric oxygen organ preservation system (HOOPS) |
| US6677150B2 (en) * | 2001-09-14 | 2004-01-13 | Organ Transport Systems, Inc. | Organ preservation apparatus and methods |
| US6810367B2 (en) * | 2002-08-08 | 2004-10-26 | Agilent Technologies, Inc. | Method and apparatus for responding to threshold events from heterogeneous measurement sources |
| US7691622B2 (en) * | 2003-04-04 | 2010-04-06 | Lifeline Scientific, Inc. | Method and apparatus for transferring heat to or from an organ or tissue container |
-
2001
- 2001-09-14 US US09/953,338 patent/US6677150B2/en not_active Expired - Lifetime
-
2002
- 2002-09-12 ES ES02798949T patent/ES2348466T3/es not_active Expired - Lifetime
- 2002-09-12 WO PCT/US2002/028970 patent/WO2003024214A1/en not_active Application Discontinuation
- 2002-09-12 AT AT02798949T patent/ATE469548T1/de active
- 2002-09-12 EP EP02798949A patent/EP1435777B1/en not_active Expired - Lifetime
- 2002-09-12 DE DE60236607T patent/DE60236607D1/de not_active Expired - Lifetime
-
2003
- 2003-10-23 US US10/692,394 patent/US7176015B2/en not_active Expired - Lifetime
-
2004
- 2004-04-13 ZA ZA200402794A patent/ZA200402794B/en unknown
-
2007
- 2007-02-13 US US11/674,549 patent/US20080038811A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040082057A1 (en) | 2004-04-29 |
| US20080038811A1 (en) | 2008-02-14 |
| DE60236607D1 (de) | 2010-07-15 |
| ATE469548T1 (de) | 2010-06-15 |
| WO2003024214A1 (en) | 2003-03-27 |
| ES2348466T3 (es) | 2010-12-07 |
| US20030054540A1 (en) | 2003-03-20 |
| US7176015B2 (en) | 2007-02-13 |
| EP1435777A1 (en) | 2004-07-14 |
| EP1435777B1 (en) | 2010-06-02 |
| EP1435777A4 (en) | 2004-11-24 |
| US6677150B2 (en) | 2004-01-13 |
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