ZA200308859B - Pyrimidine, triazine and pyrazine derivatives as glutamate receptors. - Google Patents

Pyrimidine, triazine and pyrazine derivatives as glutamate receptors. Download PDF

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Publication number
ZA200308859B
ZA200308859B ZA200308859A ZA200308859A ZA200308859B ZA 200308859 B ZA200308859 B ZA 200308859B ZA 200308859 A ZA200308859 A ZA 200308859A ZA 200308859 A ZA200308859 A ZA 200308859A ZA 200308859 B ZA200308859 B ZA 200308859B
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South Africa
Prior art keywords
phenyl
carbonitrile
pyrimidine
formula
fluoro
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ZA200308859A
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English (en)
Inventor
Alfred Binggeli
Thierry Masquelin
Maurice Wilhelm
Hans-Peter Maerki
Vincent Mutel
Wolfgang Wostl
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Hoffmann La Roche
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Publication of ZA200308859B publication Critical patent/ZA200308859B/en

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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ZA200308859A 2001-06-01 2003-11-13 Pyrimidine, triazine and pyrazine derivatives as glutamate receptors. ZA200308859B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01113379 2001-06-01

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Publication Number Publication Date
ZA200308859B true ZA200308859B (en) 2005-02-14

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ZA200308859A ZA200308859B (en) 2001-06-01 2003-11-13 Pyrimidine, triazine and pyrazine derivatives as glutamate receptors.

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US (1) US6673795B2 (enExample)
EP (1) EP1397351B1 (enExample)
JP (1) JP4049742B2 (enExample)
KR (1) KR100602927B1 (enExample)
CN (1) CN1245391C (enExample)
AR (1) AR036075A1 (enExample)
AT (1) ATE448210T1 (enExample)
AU (1) AU2002319183B2 (enExample)
BR (1) BR0210102A (enExample)
CA (1) CA2448602C (enExample)
DE (1) DE60234338D1 (enExample)
DK (1) DK1397351T3 (enExample)
ES (1) ES2332505T3 (enExample)
MX (1) MXPA03010822A (enExample)
PT (1) PT1397351E (enExample)
WO (1) WO2002098864A1 (enExample)
ZA (1) ZA200308859B (enExample)

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JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
CN105153042B (zh) * 2015-07-17 2017-11-24 四川大学 一种化合物及其在制备治疗可卡因成瘾的药物中的用途
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
CN110520127B (zh) * 2017-03-26 2023-05-16 武田药品工业株式会社 作为gpr6的调节剂的经哌啶基取代的杂芳族羧酰胺和经哌嗪基取代的杂芳族羧酰胺
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法
WO2026032256A1 (zh) * 2024-08-06 2026-02-12 上海齐鲁制药研究中心有限公司 单环类gpr6反向激动剂及其用途

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