ZA200308600B - Kappa opiate agonists for the treatment of bladder diseases. - Google Patents

Kappa opiate agonists for the treatment of bladder diseases. Download PDF

Info

Publication number
ZA200308600B
ZA200308600B ZA200308600A ZA200308600A ZA200308600B ZA 200308600 B ZA200308600 B ZA 200308600B ZA 200308600 A ZA200308600 A ZA 200308600A ZA 200308600 A ZA200308600 A ZA 200308600A ZA 200308600 B ZA200308600 B ZA 200308600B
Authority
ZA
South Africa
Prior art keywords
treatment
bladder
phenyl
diphenylacetamide
hydroxypyrrolidin
Prior art date
Application number
ZA200308600A
Other languages
English (en)
Inventor
Jutta Jacob
Gerd Bartoszyk
Frank Weber
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200308600B publication Critical patent/ZA200308600B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200308600A 2001-04-05 2003-11-04 Kappa opiate agonists for the treatment of bladder diseases. ZA200308600B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10116978A DE10116978A1 (de) 2001-04-05 2001-04-05 Kappa-Opiatagonisten für die Behandlung von Erkrankungen der Blase

Publications (1)

Publication Number Publication Date
ZA200308600B true ZA200308600B (en) 2004-09-13

Family

ID=7680492

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200308600A ZA200308600B (en) 2001-04-05 2003-11-04 Kappa opiate agonists for the treatment of bladder diseases.

Country Status (23)

Country Link
US (1) US20040157913A1 (cs)
EP (2) EP1397128B1 (cs)
JP (1) JP2004525165A (cs)
KR (1) KR100851938B1 (cs)
CN (1) CN1268332C (cs)
AT (1) ATE366109T1 (cs)
AU (1) AU2002254947B2 (cs)
BR (1) BR0208488A (cs)
CA (1) CA2443019C (cs)
CY (1) CY1109001T1 (cs)
CZ (1) CZ20032899A3 (cs)
DE (2) DE10116978A1 (cs)
DK (1) DK1397128T3 (cs)
ES (1) ES2290286T3 (cs)
HU (1) HUP0303910A3 (cs)
MX (1) MXPA03009099A (cs)
MY (1) MY136683A (cs)
PL (1) PL363540A1 (cs)
PT (1) PT1397128E (cs)
RU (1) RU2307651C2 (cs)
SK (1) SK13272003A3 (cs)
WO (1) WO2002080905A1 (cs)
ZA (1) ZA200308600B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10259245A1 (de) * 2002-12-17 2004-07-01 Merck Patent Gmbh Derivate des Asimadolins mit kovalent gebundenen Säuren
EP1680115A1 (en) * 2003-10-30 2006-07-19 Tioga Pharmaceuticals, Inc. Use of selective opiate receptor modulators in the treatment of neuropathy
SI2136801T1 (sl) 2007-03-30 2013-01-31 Tioga Pharmaceuticals, Inc. Kappa-opiat agonisti za zdravljenje diareje-predominant in izmeniäśnega sindroma razdraĺ˝ljivih prebavil
NZ630471A (en) * 2012-03-19 2016-04-29 Wellesley Pharmaceuticals Llc Extended-release formulation for reducing the frequency of urination and method of use thereof
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
US8987289B2 (en) 2012-12-14 2015-03-24 Trevi Therapeutics, Inc. Methods for treating pruritus
US8637538B1 (en) 2012-12-14 2014-01-28 Trevi Therapeutics, Inc. Methods for treatment of pruritis
AU2019309913B2 (en) 2018-07-23 2025-02-27 Trevi Therapeutics, Inc. Treatment of chronic cough, breathlessness and dyspnea
EP4087569A4 (en) 2020-01-10 2024-01-24 Trevi Therapeutics, Inc. METHODS OF ADMINISTRATION OF NALBUPHINE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6A (en) * 1836-08-10 Thomas Blanchard Machine for forming end pieces of plank blocks for ships
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
DE4215213A1 (de) * 1992-05-09 1993-11-11 Merck Patent Gmbh Arylacetamide
IL106142A (en) * 1992-06-29 1997-03-18 Merck & Co Inc Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
DE19523502A1 (de) * 1995-06-28 1997-01-02 Merck Patent Gmbh Kappa-Opiatagonisten für entzündliche Darmerkrankungen
DE19531464A1 (de) * 1995-08-26 1997-02-27 Merck Patent Gmbh N-Methyl-N-[(1S-)-1-phenyl-2-((3S)-3-hydroxypyrrolidin 1-yl-)-ethyl]-2,2-diphenyl-acetamid
US5859043A (en) * 1996-06-11 1999-01-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for maintaining kidney function during surgery or severe trauma under general anesthesia
US6201022B1 (en) * 1997-03-27 2001-03-13 Myorx, Inc. Methods for treating neurotransmitter-mediated pain syndromes by topically administering an omega fatty acid
US5965701A (en) * 1997-12-23 1999-10-12 Ferring Bv Kappa receptor opioid peptides

Also Published As

Publication number Publication date
MY136683A (en) 2008-11-28
RU2307651C2 (ru) 2007-10-10
EP1834640A2 (de) 2007-09-19
KR100851938B1 (ko) 2008-08-12
MXPA03009099A (es) 2004-02-12
EP1397128A1 (de) 2004-03-17
DE10116978A1 (de) 2002-10-10
CN1499967A (zh) 2004-05-26
RU2003130641A (ru) 2005-03-10
EP1834640A3 (de) 2009-12-23
SK13272003A3 (sk) 2004-02-03
BR0208488A (pt) 2004-03-02
ES2290286T3 (es) 2008-02-16
WO2002080905A1 (de) 2002-10-17
HUP0303910A3 (en) 2005-04-28
EP1397128B1 (de) 2007-07-04
AU2002254947B2 (en) 2007-06-07
HUP0303910A2 (hu) 2004-03-29
JP2004525165A (ja) 2004-08-19
ATE366109T1 (de) 2007-07-15
DK1397128T3 (da) 2007-10-15
PT1397128E (pt) 2007-09-03
CN1268332C (zh) 2006-08-09
US20040157913A1 (en) 2004-08-12
CA2443019A1 (en) 2002-10-17
DE50210422D1 (de) 2007-08-16
CZ20032899A3 (cs) 2004-06-16
CY1109001T1 (el) 2014-07-02
PL363540A1 (en) 2004-11-29
KR20040025909A (ko) 2004-03-26
HK1064036A1 (en) 2005-01-21
CA2443019C (en) 2009-12-29

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