ZA200307468B - Modified thrombopoietin with reduced immunogenicity. - Google Patents
Modified thrombopoietin with reduced immunogenicity. Download PDFInfo
- Publication number
- ZA200307468B ZA200307468B ZA200307468A ZA200307468A ZA200307468B ZA 200307468 B ZA200307468 B ZA 200307468B ZA 200307468 A ZA200307468 A ZA 200307468A ZA 200307468 A ZA200307468 A ZA 200307468A ZA 200307468 B ZA200307468 B ZA 200307468B
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- South Africa
- Prior art keywords
- amino acid
- molecule
- peptide
- binding
- modified
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01104702 | 2001-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200307468B true ZA200307468B (en) | 2004-07-02 |
Family
ID=8176606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200307468A ZA200307468B (en) | 2001-02-26 | 2003-09-25 | Modified thrombopoietin with reduced immunogenicity. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040071688A1 (hu) |
| EP (1) | EP1364011A2 (hu) |
| JP (1) | JP2004533812A (hu) |
| KR (1) | KR20030077632A (hu) |
| CN (1) | CN1494590A (hu) |
| BR (1) | BR0207542A (hu) |
| CA (1) | CA2439168A1 (hu) |
| HU (1) | HUP0401121A3 (hu) |
| MX (1) | MXPA03007625A (hu) |
| PL (1) | PL363520A1 (hu) |
| RU (1) | RU2003127409A (hu) |
| WO (1) | WO2002068469A2 (hu) |
| ZA (1) | ZA200307468B (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005000891A2 (en) * | 2003-06-26 | 2005-01-06 | Merck Patent Gmbh | Thrombopoietin proteins with improved properties |
| US7879318B2 (en) * | 2006-01-23 | 2011-02-01 | Mcw Research Foundation, Inc. | Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand |
| CA2691539C (en) * | 2007-06-21 | 2014-08-26 | Angelica Therapeutics, Inc. | Modified toxins |
| WO2009110944A1 (en) * | 2008-02-29 | 2009-09-11 | Angelica Therapeutics, Inc. | Modified toxins |
| WO2010085086A2 (ko) * | 2009-01-20 | 2010-07-29 | 한올바이오파마 주식회사 | 변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법 |
| CA2902905A1 (en) | 2013-03-15 | 2014-09-25 | Claude Geoffrey Davis | Modified toxins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0668352A1 (en) * | 1994-02-14 | 1995-08-23 | Kirin Brewery Company, Ltd. | Protein having TPO activity |
| US6254870B1 (en) * | 1995-02-03 | 2001-07-03 | G. D. Searle & Co. | Thrombopoietin: IL-3 fusion protein |
-
2002
- 2002-02-22 PL PL02363520A patent/PL363520A1/xx unknown
- 2002-02-22 BR BR0207542-3A patent/BR0207542A/pt not_active IP Right Cessation
- 2002-02-22 KR KR10-2003-7010859A patent/KR20030077632A/ko not_active Application Discontinuation
- 2002-02-22 EP EP02726116A patent/EP1364011A2/en not_active Withdrawn
- 2002-02-22 HU HU0401121A patent/HUP0401121A3/hu unknown
- 2002-02-22 WO PCT/EP2002/001931 patent/WO2002068469A2/en not_active Application Discontinuation
- 2002-02-22 MX MXPA03007625A patent/MXPA03007625A/es unknown
- 2002-02-22 US US10/469,101 patent/US20040071688A1/en not_active Abandoned
- 2002-02-22 RU RU2003127409/13A patent/RU2003127409A/ru not_active Application Discontinuation
- 2002-02-22 CA CA002439168A patent/CA2439168A1/en not_active Abandoned
- 2002-02-22 CN CNA028055772A patent/CN1494590A/zh active Pending
- 2002-02-22 JP JP2002567979A patent/JP2004533812A/ja not_active Withdrawn
-
2003
- 2003-09-25 ZA ZA200307468A patent/ZA200307468B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1364011A2 (en) | 2003-11-26 |
| KR20030077632A (ko) | 2003-10-01 |
| PL363520A1 (en) | 2004-11-29 |
| CA2439168A1 (en) | 2002-09-06 |
| BR0207542A (pt) | 2004-03-09 |
| WO2002068469A3 (en) | 2003-08-28 |
| JP2004533812A (ja) | 2004-11-11 |
| US20040071688A1 (en) | 2004-04-15 |
| WO2002068469A2 (en) | 2002-09-06 |
| HUP0401121A3 (en) | 2006-01-30 |
| CN1494590A (zh) | 2004-05-05 |
| RU2003127409A (ru) | 2005-04-10 |
| MXPA03007625A (es) | 2003-12-04 |
| HUP0401121A2 (hu) | 2004-09-28 |
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