MXPA03007625A - Trombopoyetina modificada con inmunogenicidad reducida. - Google Patents

Trombopoyetina modificada con inmunogenicidad reducida.

Info

Publication number
MXPA03007625A
MXPA03007625A MXPA03007625A MXPA03007625A MXPA03007625A MX PA03007625 A MXPA03007625 A MX PA03007625A MX PA03007625 A MXPA03007625 A MX PA03007625A MX PA03007625 A MXPA03007625 A MX PA03007625A MX PA03007625 A MXPA03007625 A MX PA03007625A
Authority
MX
Mexico
Prior art keywords
reduced immunogenicity
thrombopoietin
modified
modified thrombopoietin
immunogenicity
Prior art date
Application number
MXPA03007625A
Other languages
English (en)
Inventor
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of MXPA03007625A publication Critical patent/MXPA03007625A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MXPA03007625A 2001-02-26 2002-02-22 Trombopoyetina modificada con inmunogenicidad reducida. MXPA03007625A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01104702 2001-02-26
PCT/EP2002/001931 WO2002068469A2 (en) 2001-02-26 2002-02-22 Modified thrombopoietin with reduced immunogenicity

Publications (1)

Publication Number Publication Date
MXPA03007625A true MXPA03007625A (es) 2003-12-04

Family

ID=8176606

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03007625A MXPA03007625A (es) 2001-02-26 2002-02-22 Trombopoyetina modificada con inmunogenicidad reducida.

Country Status (13)

Country Link
US (1) US20040071688A1 (es)
EP (1) EP1364011A2 (es)
JP (1) JP2004533812A (es)
KR (1) KR20030077632A (es)
CN (1) CN1494590A (es)
BR (1) BR0207542A (es)
CA (1) CA2439168A1 (es)
HU (1) HUP0401121A3 (es)
MX (1) MXPA03007625A (es)
PL (1) PL363520A1 (es)
RU (1) RU2003127409A (es)
WO (1) WO2002068469A2 (es)
ZA (1) ZA200307468B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1636261B1 (en) * 2003-06-26 2007-08-01 MERCK PATENT GmbH Thrombopoietin proteins with improved properties
US7879318B2 (en) * 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
US8252897B2 (en) * 2007-06-21 2012-08-28 Angelica Therapeutics, Inc. Modified toxins
WO2009110944A1 (en) * 2008-02-29 2009-09-11 Angelica Therapeutics, Inc. Modified toxins
US20110294733A1 (en) * 2009-01-20 2011-12-01 Hanall Biopharma Co., Ltd. Modified human thrombopoietin polypeptide fragment and manufacturing method thereof
US10059750B2 (en) 2013-03-15 2018-08-28 Angelica Therapeutics, Inc. Modified toxins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG79882A1 (en) * 1994-02-14 2001-04-17 Kirin Brewery Protein having tpo activity
EP0807181A1 (en) * 1995-02-03 1997-11-19 G.D. Searle & Co. NOVEL c-MPL LIGANDS

Also Published As

Publication number Publication date
HUP0401121A3 (en) 2006-01-30
BR0207542A (pt) 2004-03-09
WO2002068469A3 (en) 2003-08-28
PL363520A1 (en) 2004-11-29
HUP0401121A2 (hu) 2004-09-28
JP2004533812A (ja) 2004-11-11
ZA200307468B (en) 2004-07-02
KR20030077632A (ko) 2003-10-01
US20040071688A1 (en) 2004-04-15
WO2002068469A2 (en) 2002-09-06
EP1364011A2 (en) 2003-11-26
RU2003127409A (ru) 2005-04-10
CN1494590A (zh) 2004-05-05
CA2439168A1 (en) 2002-09-06

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