HUP0401121A3 - Modified thrombopoietin with reduced immunogenicity - Google Patents

Modified thrombopoietin with reduced immunogenicity

Info

Publication number
HUP0401121A3
HUP0401121A3 HU0401121A HUP0401121A HUP0401121A3 HU P0401121 A3 HUP0401121 A3 HU P0401121A3 HU 0401121 A HU0401121 A HU 0401121A HU P0401121 A HUP0401121 A HU P0401121A HU P0401121 A3 HUP0401121 A3 HU P0401121A3
Authority
HU
Hungary
Prior art keywords
reduced immunogenicity
thrombopoietin
modified
modified thrombopoietin
immunogenicity
Prior art date
Application number
HU0401121A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP0401121A2 publication Critical patent/HUP0401121A2/hu
Publication of HUP0401121A3 publication Critical patent/HUP0401121A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU0401121A 2001-02-26 2002-02-22 Modified thrombopoietin with reduced immunogenicity HUP0401121A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01104702 2001-02-26
PCT/EP2002/001931 WO2002068469A2 (en) 2001-02-26 2002-02-22 Modified thrombopoietin with reduced immunogenicity

Publications (2)

Publication Number Publication Date
HUP0401121A2 HUP0401121A2 (hu) 2004-09-28
HUP0401121A3 true HUP0401121A3 (en) 2006-01-30

Family

ID=8176606

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401121A HUP0401121A3 (en) 2001-02-26 2002-02-22 Modified thrombopoietin with reduced immunogenicity

Country Status (13)

Country Link
US (1) US20040071688A1 (hu)
EP (1) EP1364011A2 (hu)
JP (1) JP2004533812A (hu)
KR (1) KR20030077632A (hu)
CN (1) CN1494590A (hu)
BR (1) BR0207542A (hu)
CA (1) CA2439168A1 (hu)
HU (1) HUP0401121A3 (hu)
MX (1) MXPA03007625A (hu)
PL (1) PL363520A1 (hu)
RU (1) RU2003127409A (hu)
WO (1) WO2002068469A2 (hu)
ZA (1) ZA200307468B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005000891A2 (en) * 2003-06-26 2005-01-06 Merck Patent Gmbh Thrombopoietin proteins with improved properties
US7879318B2 (en) * 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
CA2691539C (en) * 2007-06-21 2014-08-26 Angelica Therapeutics, Inc. Modified toxins
WO2009110944A1 (en) * 2008-02-29 2009-09-11 Angelica Therapeutics, Inc. Modified toxins
WO2010085086A2 (ko) * 2009-01-20 2010-07-29 한올바이오파마 주식회사 변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법
CA2902905A1 (en) 2013-03-15 2014-09-25 Claude Geoffrey Davis Modified toxins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0668352A1 (en) * 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein having TPO activity
US6254870B1 (en) * 1995-02-03 2001-07-03 G. D. Searle & Co. Thrombopoietin: IL-3 fusion protein

Also Published As

Publication number Publication date
EP1364011A2 (en) 2003-11-26
KR20030077632A (ko) 2003-10-01
PL363520A1 (en) 2004-11-29
CA2439168A1 (en) 2002-09-06
BR0207542A (pt) 2004-03-09
WO2002068469A3 (en) 2003-08-28
JP2004533812A (ja) 2004-11-11
US20040071688A1 (en) 2004-04-15
ZA200307468B (en) 2004-07-02
WO2002068469A2 (en) 2002-09-06
CN1494590A (zh) 2004-05-05
RU2003127409A (ru) 2005-04-10
MXPA03007625A (es) 2003-12-04
HUP0401121A2 (hu) 2004-09-28

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees