ZA200305875B - Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus. - Google Patents
Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus. Download PDFInfo
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- ZA200305875B ZA200305875B ZA200305875A ZA200305875A ZA200305875B ZA 200305875 B ZA200305875 B ZA 200305875B ZA 200305875 A ZA200305875 A ZA 200305875A ZA 200305875 A ZA200305875 A ZA 200305875A ZA 200305875 B ZA200305875 B ZA 200305875B
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- reovirus
- chemotherapeutic agent
- virus
- ras
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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- Reproductive Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US27036301P | 2001-02-20 | 2001-02-20 |
Publications (1)
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ZA200305875B true ZA200305875B (en) | 2004-07-30 |
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Family Applications (1)
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ZA200305875A ZA200305875B (en) | 2001-02-20 | 2003-07-30 | Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus. |
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US (5) | US7264798B2 (fr) |
EP (2) | EP1361884B1 (fr) |
JP (3) | JP4951194B2 (fr) |
AR (1) | AR035227A1 (fr) |
AT (1) | ATE516807T1 (fr) |
AU (2) | AU2002234453B2 (fr) |
BR (1) | BR0207691A (fr) |
CA (1) | CA2437468C (fr) |
DK (1) | DK1361884T3 (fr) |
ES (1) | ES2367768T3 (fr) |
HK (1) | HK1060520A1 (fr) |
IL (2) | IL157167A0 (fr) |
MX (1) | MXPA03007486A (fr) |
NZ (2) | NZ527399A (fr) |
WO (1) | WO2002066040A2 (fr) |
ZA (1) | ZA200305875B (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
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US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
CA2482826C (fr) | 2002-05-10 | 2011-11-22 | Oncolytics Biotech Inc. | Sensibilisation de cellules neoplasiques a une radiotherapie au moyen de virus oncolytiques |
CA2522711A1 (fr) * | 2003-04-25 | 2004-11-11 | Wellstat Biologics Corporation | Utilisation de virus therapeutiques pour le traitement des carcinomes hepatocellulaires |
SG179291A1 (en) | 2003-06-18 | 2012-04-27 | Genelux Corp | Modified recombinant vaccinia viruses and other microorganisms, uses thereof |
CA2562904C (fr) | 2004-04-27 | 2013-07-02 | Wellstat Biologics Corporation | Traitement de cancers utilisant des virus et des camptothecines |
WO2005112966A1 (fr) * | 2004-05-21 | 2005-12-01 | Orison Biotechnology Inc. | Thérapie combinée extrait végétal plus un réovirus pour tuer les cellules néoplasiques chez un sujet |
US7767200B2 (en) * | 2005-07-14 | 2010-08-03 | Wellstat Biologics Corporation | Cancer treatment using viruses, fluoropyrimidines and camptothecins |
US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
CA2617600A1 (fr) * | 2005-08-01 | 2007-09-07 | University Technologies International, Inc. | Reovirus attenue |
PT1951274E (pt) * | 2005-11-24 | 2009-12-14 | Aicuris Gmbh & Co Kg | Parapoxvírus em combinação com agentes quimioterapêuticos citotóxicos clássicos como bioquimioterapia para o tratamento de cancro |
US20090098529A1 (en) | 2006-10-16 | 2009-04-16 | Nanhai Chen | Methods for attenuating virus strains for diagnostic and therapeutic uses |
US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8178564B2 (en) * | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
WO2008150496A2 (fr) * | 2007-05-31 | 2008-12-11 | Genelux Corporation | Essai de sensibilité à des agents chimiothérapeutiques |
TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
WO2009011924A1 (fr) * | 2007-07-18 | 2009-01-22 | Genelux Corporation | Utilisation d'un agent chimiothérapeutique dans la préparation d'un médicament pour traiter ou améliorer un effet secondaire indésirable associé à une thérapie virale oncolytique. |
CN101820892A (zh) * | 2007-10-22 | 2010-09-01 | 昂科利蒂克斯生物科技公司 | 增殖性疾病的治疗方案 |
US20110053879A1 (en) * | 2008-02-08 | 2011-03-03 | Poniard Pharmaceuticals, Inc. | Picoplatin and amrubicin to treat lung cancer |
US20120052003A9 (en) * | 2008-05-16 | 2012-03-01 | Szalay Aladar A | Microorganisms for preventing and treating neoplasms accompanying cellular therapy |
JP5748656B2 (ja) * | 2008-05-22 | 2015-07-15 | ジェ イル ファーマシューティカル カンパニー リミテッド | 過剰増殖細胞の腫瘍抑制因子に基づいた腫瘍崩壊ウイルスに対する感受性を判定する方法 |
TW200950777A (en) * | 2008-05-27 | 2009-12-16 | Oncolytics Biotech Inc | Abrogating proinflammatory cytokine production during oncolytic reovirus therapy |
WO2009143610A1 (fr) * | 2008-05-27 | 2009-12-03 | Oncolytics Biotech Inc. | Modulation de la pression interstitielle et administration et distribution de virus oncolytiques |
WO2013163724A1 (fr) * | 2012-04-30 | 2013-11-07 | Oncolytics Biotech Inc. | Protection de virus modifiés contre des anticorps neutralisants utilisant la protéine sigma 1 de réovirus |
EP3209382B1 (fr) | 2014-10-24 | 2020-11-25 | Calidi Biotherapeutics, Inc. | Technique d'immunotherapie combinee pour le traitement du cancer |
CN104881181B (zh) * | 2015-05-27 | 2019-07-26 | 联想(北京)有限公司 | 显示方法及电子设备 |
CA3177862A1 (fr) | 2018-11-06 | 2020-05-14 | Calidi Biotherapeutics, Inc. | Systemes ameliores pour therapie virale oncolytique a mediation cellulaire |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0931830T3 (da) | 1993-02-16 | 2001-06-11 | Onyx Pharma Inc | Cytopatiske vira til terapi og profylakse af neoplasi |
PT1314431E (pt) | 1993-04-30 | 2008-10-24 | Wellstat Biologics Corp | Composições purificadas de vírus da doença de newcastle |
US5776743A (en) | 1994-09-06 | 1998-07-07 | La Jolla Cancer Research Foundation | Method of sensitizing tumor cells with adenovirus E1A |
US6110461A (en) | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
ATE371372T1 (de) | 1997-10-09 | 2007-09-15 | Wellstat Biologics Corp | Behandlung von neoplasmen mit interferon- empfindlichen, klonalen viren |
US6428968B1 (en) * | 1999-03-15 | 2002-08-06 | The Trustees Of The University Of Pennsylvania | Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject |
EP1955703A1 (fr) * | 1999-11-12 | 2008-08-13 | Oncolytics Biotech Inc. | Virus pour le traitement des troubles proliférants cellulaires |
AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
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- 2002-02-19 AT AT02701122T patent/ATE516807T1/de not_active IP Right Cessation
- 2002-02-19 JP JP2002565598A patent/JP4951194B2/ja not_active Expired - Lifetime
- 2002-02-19 EP EP10013901A patent/EP2314301A3/fr not_active Withdrawn
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2003
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- 2003-07-30 ZA ZA200305875A patent/ZA200305875B/en unknown
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2004
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2007
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2008
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2011
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2012
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- 2012-09-24 US US13/625,259 patent/US8658158B2/en not_active Expired - Lifetime
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