ZA200302086B - Methods for the treatment of cellular proliferative disorders. - Google Patents
Methods for the treatment of cellular proliferative disorders. Download PDFInfo
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- ZA200302086B ZA200302086B ZA200302086A ZA200302086A ZA200302086B ZA 200302086 B ZA200302086 B ZA 200302086B ZA 200302086 A ZA200302086 A ZA 200302086A ZA 200302086 A ZA200302086 A ZA 200302086A ZA 200302086 B ZA200302086 B ZA 200302086B
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- reovirus
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
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- C12N2720/12011—Reoviridae
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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- G—PHYSICS
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- G01N2333/08—RNA viruses
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Landscapes
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Applications Claiming Priority (1)
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US24672800P | 2000-11-09 | 2000-11-09 |
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ZA200302086A ZA200302086B (en) | 2000-11-09 | 2003-03-14 | Methods for the treatment of cellular proliferative disorders. |
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EP (2) | EP2189162B1 (ja) |
JP (2) | JP4146725B2 (ja) |
AR (1) | AR031281A1 (ja) |
AT (1) | ATE472733T1 (ja) |
AU (2) | AU2002212022B2 (ja) |
BR (1) | BR0115235A (ja) |
CA (1) | CA2428206C (ja) |
DE (1) | DE60142485D1 (ja) |
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ES (2) | ES2445704T3 (ja) |
HK (1) | HK1142833A1 (ja) |
IL (1) | IL154881A0 (ja) |
MX (1) | MXPA03004029A (ja) |
NZ (1) | NZ524937A (ja) |
WO (1) | WO2002039117A1 (ja) |
ZA (1) | ZA200302086B (ja) |
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US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
US7306902B2 (en) | 2002-06-28 | 2007-12-11 | Oncolyties Biotech Inc. | Oncolytic viruses as phenotyping agents for neoplasms |
US8491884B2 (en) | 2000-05-03 | 2013-07-23 | Oncolytics Biotech Inc. | Virus clearance of neoplastic cells from mixed cellular compositions |
US20040115170A1 (en) * | 2001-11-30 | 2004-06-17 | Brown Earl Garnet | Oncolytic virus |
AR053272A1 (es) | 2005-05-11 | 2007-04-25 | Hoffmann La Roche | Determinacion de responsivos a la quimioterapia |
EP1917351A4 (en) | 2005-08-01 | 2009-12-16 | Univ Technologies Int | ATTENUATED REOVIRUS |
US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
US20070190032A1 (en) * | 2006-02-13 | 2007-08-16 | Oncolytics Biotech Inc. | Use of Local Immune Suppression to Enhance Oncolytic Viral Therapy |
WO2008031230A1 (en) * | 2006-09-15 | 2008-03-20 | Dalhousie University | Methods of determining susceptibility of cells to reovirus infection and methods for treating cellular proliferative disorders with reovirus |
EP2952583A1 (en) | 2007-03-12 | 2015-12-09 | Oncolytics Biotech Inc. | Reoviruses having modified sequences |
US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
AR066649A1 (es) * | 2007-05-21 | 2009-09-02 | Oncolytics Biotech Inc | Reovirus mutantes y metodos de elaboracion y uso de los mismos |
WO2009052617A1 (en) * | 2007-10-22 | 2009-04-30 | Oncolytics Biotech Inc. | Treatment regime for proliferative disorders |
TWI399369B (zh) | 2008-04-02 | 2013-06-21 | Nat Defense Medical Ct | 咪唑蒽醌衍生物及其合成方法 |
TW200950777A (en) * | 2008-05-27 | 2009-12-16 | Oncolytics Biotech Inc | Abrogating proinflammatory cytokine production during oncolytic reovirus therapy |
CA2689707A1 (en) | 2009-11-16 | 2011-05-16 | Jean-Simon Diallo | Identification of the novel small molecule viral sensitizer vse1 using high-throughput screening |
EP3250550B1 (en) | 2015-01-26 | 2023-04-05 | Ottawa Hospital Research Institute | Compositions and methods for viral sensitization |
CN110022889B (zh) | 2016-10-03 | 2024-05-10 | 渥太华医院研究所 | 用于提高溶瘤rna病毒的生长、传播和溶瘤与免疫治疗效果的组合物和方法 |
CA2971832A1 (en) * | 2017-06-23 | 2018-12-23 | Roy Duncan | Recombinant oncolytic viruses for treatment of metastatic cancers |
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US5023252A (en) * | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
US6136307A (en) | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
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2001
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AU1202202A (en) | 2002-05-21 |
EP1332366A1 (en) | 2003-08-06 |
JP2004512385A (ja) | 2004-04-22 |
BR0115235A (pt) | 2003-10-14 |
NZ524937A (en) | 2004-10-29 |
CA2428206A1 (en) | 2002-05-16 |
IL154881A0 (en) | 2003-10-31 |
EP2189162A1 (en) | 2010-05-26 |
US7815914B2 (en) | 2010-10-19 |
EP1332366B1 (en) | 2010-06-30 |
US20080057073A1 (en) | 2008-03-06 |
JP4146725B2 (ja) | 2008-09-10 |
DE60142485D1 (de) | 2010-08-12 |
ES2445704T3 (es) | 2014-03-04 |
AR031281A1 (es) | 2003-09-17 |
JP2008268200A (ja) | 2008-11-06 |
CA2428206C (en) | 2005-09-27 |
AU2002212022B2 (en) | 2006-03-30 |
US7763252B2 (en) | 2010-07-27 |
MXPA03004029A (es) | 2004-02-12 |
HK1142833A1 (en) | 2010-12-17 |
ES2347523T3 (es) | 2010-11-02 |
ATE472733T1 (de) | 2010-07-15 |
DK2189162T3 (da) | 2014-02-03 |
DK1332366T3 (da) | 2010-08-02 |
WO2002039117A1 (en) | 2002-05-16 |
EP2189162B1 (en) | 2013-11-27 |
US20020086284A1 (en) | 2002-07-04 |
US7052832B2 (en) | 2006-05-30 |
US20060172288A1 (en) | 2006-08-03 |
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