ZA200209474B - Novel MMP-2/MMP-9 inhibitors. - Google Patents
Novel MMP-2/MMP-9 inhibitors. Download PDFInfo
- Publication number
- ZA200209474B ZA200209474B ZA200209474A ZA200209474A ZA200209474B ZA 200209474 B ZA200209474 B ZA 200209474B ZA 200209474 A ZA200209474 A ZA 200209474A ZA 200209474 A ZA200209474 A ZA 200209474A ZA 200209474 B ZA200209474 B ZA 200209474B
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- ZA
- South Africa
- Prior art keywords
- pain
- mmp
- acid
- nonylsuccinic acid
- nonylsuccinic
- Prior art date
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- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20675400P | 2000-05-24 | 2000-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200209474B true ZA200209474B (en) | 2003-07-29 |
Family
ID=22767798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200209474A ZA200209474B (en) | 2000-05-24 | 2002-11-21 | Novel MMP-2/MMP-9 inhibitors. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20030225272A1 (no) |
| EP (1) | EP1283823A4 (no) |
| JP (1) | JP2003534308A (no) |
| KR (1) | KR20030017523A (no) |
| CN (1) | CN1430597A (no) |
| AR (1) | AR028606A1 (no) |
| AU (1) | AU2001266605A1 (no) |
| BR (1) | BR0110902A (no) |
| CA (1) | CA2410593A1 (no) |
| CZ (1) | CZ20023850A3 (no) |
| HU (1) | HUP0302316A2 (no) |
| IL (1) | IL152658A0 (no) |
| MX (1) | MXPA02011558A (no) |
| NO (1) | NO20025605L (no) |
| PL (1) | PL359263A1 (no) |
| WO (1) | WO2001090047A1 (no) |
| ZA (1) | ZA200209474B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7354955B2 (en) * | 2004-01-07 | 2008-04-08 | Abbott Laboratories | (2S)-amino(phenyl)acetic acid and derivatives as α2δ voltage-gated calcium channel ligands |
| EP1871420A4 (en) | 2005-04-15 | 2010-09-22 | Univ North Carolina | PROCESS FOR ENABLING CELL SURVIVAL VIA NEUROTROPHINE MIMETICS |
| JP2011506614A (ja) | 2007-12-17 | 2011-03-03 | ダイアックス コーポレーション | Ｍｍｐ−１４結合タンパク質を含む、骨溶解性障害を処置するための組成物および方法 |
| WO2009111508A2 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| CA2717576A1 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 binding proteins |
| MX339096B (es) * | 2008-12-23 | 2016-05-11 | Aquilus Pharmaceuticals Inc | Compuestos inhibidores de metaloproteasa a base de feniletiniltiofeno y su uso en el tratamiento del dolor y otras enfermedades. |
| US10273219B2 (en) | 2009-11-12 | 2019-04-30 | Pharmatrophix, Inc. | Crystalline forms of neurotrophin mimetic compounds and their salts |
| AU2010319349B2 (en) | 2009-11-12 | 2015-07-16 | Pharmatrophix, Inc. | Crystalline forms of neurotrophin mimetic compounds and their salts |
| AU2011360973A1 (en) * | 2011-03-02 | 2013-09-19 | Aquilus Pharmaceuticals, Inc. | Compounds and methods for the treatment of pain and other disorders |
| WO2013059439A2 (en) | 2011-10-21 | 2013-04-25 | Dyax Corp. | Combination therapy comprising an mmp-14 binding protein |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5889058A (en) * | 1990-12-03 | 1999-03-30 | Celltech Limited | Peptidyl derivatives |
| DK0822186T3 (da) * | 1994-01-20 | 2000-06-26 | British Biotech Pharm | L-tert-leucin-2-pyridylamid |
| JP3827324B2 (ja) * | 1994-01-22 | 2006-09-27 | ブリテッシュ バイオテック ファーマシューティカルズ リミテッド | 金属タンパク質分解酵素阻害剤 |
| ATE181055T1 (de) * | 1994-05-28 | 1999-06-15 | British Biotech Pharm | Succinyl hydroxamsäure-, n-formyl-n-hydroxy- aminocarbonsäure- und succinsäureamid-derivate und ihre verwendung als metalloprotease- inhibitoren |
| GB9416897D0 (en) * | 1994-08-20 | 1994-10-12 | British Biotech Pharm | Metalloproteinase inhibitors |
| GB9423914D0 (en) * | 1994-11-26 | 1995-01-11 | British Biotech Pharm | Polyether derivatives as metalloproteinase inhibitors |
| GB9507799D0 (en) * | 1995-04-18 | 1995-05-31 | British Biotech Pharm | Metalloproteinase inhibitors |
| US6147114A (en) * | 1995-04-25 | 2000-11-14 | Fuji Yakuhin Kogyo Kabushiki Kaisha | Highly water-soluble metalloproteinase inhibitors |
| HUP9903863A3 (en) * | 1995-11-23 | 2000-11-28 | British Biotech Pharm | Metalloproteinase inhibitors |
| AUPO048296A0 (en) * | 1996-06-14 | 1996-07-11 | Fujisawa Pharmaceutical Co., Ltd. | New compound and its preparation |
| WO2001026671A1 (en) * | 1999-10-12 | 2001-04-19 | Smithkline Beecham Corporation | Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors |
-
2001
- 2001-05-22 AR ARP010102433A patent/AR028606A1/es unknown
- 2001-05-24 HU HU0302316A patent/HUP0302316A2/hu unknown
- 2001-05-24 JP JP2001586237A patent/JP2003534308A/ja not_active Withdrawn
- 2001-05-24 IL IL15265801A patent/IL152658A0/xx unknown
- 2001-05-24 KR KR1020027015895A patent/KR20030017523A/ko not_active Application Discontinuation
- 2001-05-24 EP EP01944167A patent/EP1283823A4/en not_active Withdrawn
- 2001-05-24 CN CN01810068A patent/CN1430597A/zh active Pending
- 2001-05-24 PL PL01359263A patent/PL359263A1/xx not_active Application Discontinuation
- 2001-05-24 MX MXPA02011558A patent/MXPA02011558A/es unknown
- 2001-05-24 AU AU2001266605A patent/AU2001266605A1/en not_active Abandoned
- 2001-05-24 CZ CZ20023850A patent/CZ20023850A3/cs unknown
- 2001-05-24 WO PCT/US2001/016867 patent/WO2001090047A1/en not_active Application Discontinuation
- 2001-05-24 CA CA002410593A patent/CA2410593A1/en not_active Abandoned
- 2001-05-24 BR BR0110902-2A patent/BR0110902A/pt not_active IP Right Cessation
- 2001-05-24 US US10/276,940 patent/US20030225272A1/en not_active Abandoned
-
2002
- 2002-11-21 NO NO20025605A patent/NO20025605L/no not_active Application Discontinuation
- 2002-11-21 ZA ZA200209474A patent/ZA200209474B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20025605D0 (no) | 2002-11-21 |
| IL152658A0 (en) | 2003-06-24 |
| EP1283823A1 (en) | 2003-02-19 |
| CZ20023850A3 (cs) | 2003-05-14 |
| EP1283823A4 (en) | 2005-07-27 |
| US20030225272A1 (en) | 2003-12-04 |
| PL359263A1 (en) | 2004-08-23 |
| MXPA02011558A (es) | 2003-04-25 |
| HUP0302316A2 (hu) | 2003-11-28 |
| CN1430597A (zh) | 2003-07-16 |
| AU2001266605A1 (en) | 2001-12-03 |
| JP2003534308A (ja) | 2003-11-18 |
| KR20030017523A (ko) | 2003-03-03 |
| NO20025605L (no) | 2003-01-15 |
| BR0110902A (pt) | 2003-12-30 |
| AR028606A1 (es) | 2003-05-14 |
| CA2410593A1 (en) | 2001-11-29 |
| WO2001090047A1 (en) | 2001-11-29 |
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