ZA200207757B - Use as medicine of a compound restoring active principles in vivo. - Google Patents
Use as medicine of a compound restoring active principles in vivo. Download PDFInfo
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- ZA200207757B ZA200207757B ZA200207757A ZA200207757A ZA200207757B ZA 200207757 B ZA200207757 B ZA 200207757B ZA 200207757 A ZA200207757 A ZA 200207757A ZA 200207757 A ZA200207757 A ZA 200207757A ZA 200207757 B ZA200207757 B ZA 200207757B
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- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 1
- 229960000282 metronidazole Drugs 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 229960002009 naproxen Drugs 0.000 description 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 description 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 229960001639 penicillamine Drugs 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 231100000683 possible toxicity Toxicity 0.000 description 1
- 230000003334 potential effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000019833 protease Nutrition 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229960001455 quinapril Drugs 0.000 description 1
- JSDRRTOADPPCHY-HSQYWUDLSA-N quinapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CC2=CC=CC=C2C1)C(O)=O)CC1=CC=CC=C1 JSDRRTOADPPCHY-HSQYWUDLSA-N 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 150000003333 secondary alcohols Chemical group 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
- 229960001052 streptozocin Drugs 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229960002317 succinimide Drugs 0.000 description 1
- 229960005404 sulfamethoxazole Drugs 0.000 description 1
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical compound NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 description 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical compound OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 description 1
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 230000000304 vasodilatating effect Effects 0.000 description 1
- 230000000283 vasomotion Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0017331A FR2818908B1 (fr) | 2000-12-29 | 2000-12-29 | Utilisation en tant que medicament d'un compose restituant in vivo des principes actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200207757B true ZA200207757B (en) | 2004-07-26 |
Family
ID=8858429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200207757A ZA200207757B (en) | 2000-12-29 | 2002-09-26 | Use as medicine of a compound restoring active principles in vivo. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20040058854A1 (ru) |
| EP (1) | EP1446161A2 (ru) |
| JP (1) | JP2004517106A (ru) |
| CA (1) | CA2435483A1 (ru) |
| FR (1) | FR2818908B1 (ru) |
| NZ (1) | NZ527207A (ru) |
| RU (1) | RU2003123490A (ru) |
| WO (1) | WO2002053091A2 (ru) |
| ZA (1) | ZA200207757B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070112050A1 (en) * | 2005-04-12 | 2007-05-17 | Psivida Inc. | HMGCoA reductase inhibitor combinations and uses thereof |
| EP1909848A2 (en) * | 2005-08-01 | 2008-04-16 | PSivida Inc. | HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF |
| PL2712913T3 (pl) * | 2012-09-28 | 2017-01-31 | The Procter And Gamble Company | Zewnętrzny system strukturyzujący do kompozycji ciekłego detergentu do prania |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5112954A (en) * | 1988-02-26 | 1992-05-12 | Neorx Corporation | Method of enhancing the effect of cytotoxic agents |
| US5811387A (en) * | 1990-05-15 | 1998-09-22 | Chiron Corporation | Peptoid mixtures |
| US5648344A (en) * | 1990-07-30 | 1997-07-15 | Glycomed Incorporated | Methods of treating inflammation using selection binding compounds |
| US5240693A (en) * | 1991-05-01 | 1993-08-31 | University Of New Mexico | Image enhancement by coadministration of biomodulators and structurally modified imaging agents |
| US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
| FR2696740B1 (fr) * | 1992-10-13 | 1994-12-30 | Dospharma Sa | Dérivés prodrogués de la diméthylbiguanide et applications comme médicaments. |
| WO1994029327A1 (en) * | 1993-06-07 | 1994-12-22 | British Technology Group Limited | Anticancer compounds |
| DE69433818T2 (de) * | 1994-01-28 | 2005-06-16 | The University Of Kentucky Research Foundation | Co-pharmaka als ein verfahren des kontrollierten arzneimitteltransportes |
| ATE261935T1 (de) * | 1997-12-08 | 2004-04-15 | Bristol Myers Squibb Co | Neue metformin salze und verfahren |
| PT1082109E (pt) * | 1998-04-29 | 2004-10-29 | Sumitomo Pharma | Formulacao oral que compreende biguanidina e um acido organico |
| FR2796551B1 (fr) * | 1999-07-23 | 2003-07-25 | Lipha | Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| US6624317B1 (en) * | 2000-09-25 | 2003-09-23 | The University Of North Carolina At Chapel Hill | Taxoid conjugates as antimitotic and antitumor agents |
-
2000
- 2000-12-29 FR FR0017331A patent/FR2818908B1/fr not_active Expired - Fee Related
-
2001
- 2001-12-31 CA CA002435483A patent/CA2435483A1/fr not_active Abandoned
- 2001-12-31 NZ NZ527207A patent/NZ527207A/en unknown
- 2001-12-31 EP EP01990622A patent/EP1446161A2/fr not_active Withdrawn
- 2001-12-31 WO PCT/FR2001/004236 patent/WO2002053091A2/fr active Application Filing
- 2001-12-31 RU RU2003123490/15A patent/RU2003123490A/ru not_active Application Discontinuation
- 2001-12-31 JP JP2002554042A patent/JP2004517106A/ja active Pending
- 2001-12-31 US US10/465,994 patent/US20040058854A1/en not_active Abandoned
-
2002
- 2002-09-26 ZA ZA200207757A patent/ZA200207757B/en unknown
-
2007
- 2007-07-18 US US11/879,505 patent/US20080021015A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1446161A2 (fr) | 2004-08-18 |
| US20040058854A1 (en) | 2004-03-25 |
| NZ527207A (en) | 2006-04-28 |
| RU2003123490A (ru) | 2005-01-20 |
| CA2435483A1 (fr) | 2002-07-11 |
| FR2818908A1 (fr) | 2002-07-05 |
| FR2818908B1 (fr) | 2004-04-02 |
| US20080021015A1 (en) | 2008-01-24 |
| WO2002053091A3 (fr) | 2004-06-10 |
| WO2002053091A2 (fr) | 2002-07-11 |
| JP2004517106A (ja) | 2004-06-10 |
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