ZA200204865B - Cyclic α-amino-y-hydroxyaminde compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Cyclic α-amino-y-hydroxyaminde compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200204865B
ZA200204865B ZA200204865A ZA200204865A ZA200204865B ZA 200204865 B ZA200204865 B ZA 200204865B ZA 200204865 A ZA200204865 A ZA 200204865A ZA 200204865 A ZA200204865 A ZA 200204865A ZA 200204865 B ZA200204865 B ZA 200204865B
Authority
ZA
South Africa
Prior art keywords
hydroxyaminde
cyclic
amino
compounds
preparation
Prior art date
Application number
ZA200204865A
Other languages
English (en)
Inventor
Michel Wierzbicki
Jean-Marie Fourquez
Nigel Levens
Bernadette Husson-Robert
Olivier Nosjean
Michelle Boulanger
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of ZA200204865B publication Critical patent/ZA200204865B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/14—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200204865A 2001-06-18 2002-06-18 Cyclic α-amino-y-hydroxyaminde compounds, a process for their preparation and pharmaceutical compositions containing them. ZA200204865B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0107934A FR2826003B1 (fr) 2001-06-18 2001-06-18 Nouveaux derives cycliques d'alpha-amino-gamma-hydroxy- amides, leur procede de preparation et les compositions pharmaceutiques que les contiennent

Publications (1)

Publication Number Publication Date
ZA200204865B true ZA200204865B (en) 2003-02-20

Family

ID=8864417

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200204865A ZA200204865B (en) 2001-06-18 2002-06-18 Cyclic α-amino-y-hydroxyaminde compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (25)

Country Link
US (1) US6593312B2 (pt)
EP (1) EP1270562B1 (pt)
JP (1) JP2003012642A (pt)
CN (1) CN1178901C (pt)
AR (1) AR034516A1 (pt)
AT (1) ATE277027T1 (pt)
AU (1) AU781822B2 (pt)
BR (1) BR0202313A (pt)
CA (1) CA2389858C (pt)
CZ (1) CZ20022119A3 (pt)
DE (1) DE60201296T2 (pt)
DK (1) DK1270562T3 (pt)
EA (1) EA004955B1 (pt)
ES (1) ES2229063T3 (pt)
FR (1) FR2826003B1 (pt)
HK (1) HK1050186A1 (pt)
HU (1) HUP0202011A3 (pt)
MX (1) MXPA02005997A (pt)
NO (1) NO322155B1 (pt)
NZ (1) NZ519610A (pt)
PL (1) PL354565A1 (pt)
PT (1) PT1270562E (pt)
SI (1) SI1270562T1 (pt)
SK (1) SK285989B6 (pt)
ZA (1) ZA200204865B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002306823B2 (en) * 2001-03-27 2006-05-11 Merck & Co., Inc. Dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122010000020I1 (de) * 1996-04-25 2010-07-08 Prosidion Ltd Verfahren zur Senkung des Blutglukosespiegels in Säugern

Also Published As

Publication number Publication date
EA004955B1 (ru) 2004-10-28
EP1270562A3 (fr) 2003-05-07
CN1392137A (zh) 2003-01-22
AU4882202A (en) 2002-12-19
CZ20022119A3 (cs) 2003-02-12
PT1270562E (pt) 2004-11-30
PL354565A1 (en) 2002-12-30
DE60201296T2 (de) 2006-02-23
JP2003012642A (ja) 2003-01-15
CN1178901C (zh) 2004-12-08
DE60201296D1 (de) 2004-10-28
DK1270562T3 (da) 2005-01-24
EP1270562A2 (fr) 2003-01-02
NO20022891L (no) 2002-12-19
US6593312B2 (en) 2003-07-15
FR2826003A1 (fr) 2002-12-20
EA200200574A1 (ru) 2002-12-26
HK1050186A1 (en) 2003-06-13
NZ519610A (en) 2003-05-30
FR2826003B1 (fr) 2003-08-15
HUP0202011A3 (en) 2005-07-28
BR0202313A (pt) 2003-04-29
NO20022891D0 (no) 2002-06-17
SI1270562T1 (en) 2004-12-31
CA2389858A1 (fr) 2002-12-18
SK285989B6 (sk) 2008-01-07
ATE277027T1 (de) 2004-10-15
SK8772002A3 (en) 2003-01-09
CA2389858C (fr) 2007-08-28
HU0202011D0 (pt) 2002-08-28
US20030004138A1 (en) 2003-01-02
AU781822B2 (en) 2005-06-16
EP1270562B1 (fr) 2004-09-22
ES2229063T3 (es) 2005-04-16
NO322155B1 (no) 2006-08-21
HUP0202011A2 (hu) 2003-01-28
MXPA02005997A (es) 2005-02-17
AR034516A1 (es) 2004-02-25

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