ZA200203041B - Viruses for the treatment of cellular proliferative disorders. - Google Patents
Viruses for the treatment of cellular proliferative disorders. Download PDFInfo
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- ZA200203041B ZA200203041B ZA200203041A ZA200203041A ZA200203041B ZA 200203041 B ZA200203041 B ZA 200203041B ZA 200203041 A ZA200203041 A ZA 200203041A ZA 200203041 A ZA200203041 A ZA 200203041A ZA 200203041 B ZA200203041 B ZA 200203041B
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Mycology (AREA)
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- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| US16487899P | 1999-11-12 | 1999-11-12 |
Publications (1)
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| ZA200203041B true ZA200203041B (en) | 2003-12-09 |
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Family Applications (1)
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| ZA200203041A ZA200203041B (en) | 1999-11-12 | 2000-11-08 | Viruses for the treatment of cellular proliferative disorders. |
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| US (9) | US6596268B1 (zh) |
| EP (2) | EP1227828A1 (zh) |
| JP (1) | JP2003514024A (zh) |
| AU (1) | AU782020B2 (zh) |
| BR (1) | BR0015491A (zh) |
| CA (2) | CA2388807C (zh) |
| HK (1) | HK1047698A1 (zh) |
| MX (1) | MXPA02004736A (zh) |
| NZ (1) | NZ518454A (zh) |
| WO (1) | WO2001035970A1 (zh) |
| ZA (1) | ZA200203041B (zh) |
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| AUPQ425699A0 (en) | 1999-11-25 | 1999-12-23 | University Of Newcastle Research Associates Limited, The | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
| AU777886B2 (en) * | 1999-12-08 | 2004-11-04 | Onyx Pharmaceuticals | Herpes simplex virus for treating unwanted hyperproliferative cell growth |
| AR028039A1 (es) | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas |
| US8491884B2 (en) | 2000-05-03 | 2013-07-23 | Oncolytics Biotech Inc. | Virus clearance of neoplastic cells from mixed cellular compositions |
| AR028040A1 (es) * | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de virus de celulas neoplasticas a partir de composiciones celulares mixtas |
| US7306902B2 (en) * | 2002-06-28 | 2007-12-11 | Oncolyties Biotech Inc. | Oncolytic viruses as phenotyping agents for neoplasms |
| US20020156039A1 (en) * | 2000-07-07 | 2002-10-24 | Benjamin Thomas L. | Diagnosing and treating cancer cells using Sal2 |
| US20020147996A1 (en) * | 2000-07-07 | 2002-10-10 | Benjamin Thomas L. | Diagnosing and treating cancer cells using Sal2 |
| US20030157481A1 (en) * | 2001-12-10 | 2003-08-21 | Benjamin Thomas L. | Diagnosing and treating cancer cells using T-HR mutants and their targets |
| US20050013803A1 (en) * | 2000-07-07 | 2005-01-20 | Benjamin Thomas L. | Diagnosing and treating cancer cells using mutant viruses |
| AR035227A1 (es) | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
| AU2002362072A1 (en) * | 2001-12-07 | 2003-06-23 | Board Of Regents The University Of Texas System | Use a parapox b2l protein to modify immune responses to administered antigens |
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| AU2002953436A0 (en) | 2002-12-18 | 2003-01-09 | The University Of Newcastle Research Associates Limited | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
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| US7429481B2 (en) * | 2004-09-14 | 2008-09-30 | University Of Pittsburgh | Targeting viruses using a modified sindbis glycoprotein |
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| PT1855720T (pt) | 2005-02-23 | 2016-12-14 | Bavarian Nordic As | Uso de um poxvírus modificado para a rápida indução de imunidade contra um poxvírus ou outros agentes infeciosos |
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| DK2477499T3 (en) | 2009-09-14 | 2018-06-06 | Sillajen Biotherapeutics Inc | COMBINATION CANCER THERAPY WITH ONCOLYTIC VACCINIA VIRUS |
| US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| KR101942237B1 (ko) | 2011-01-04 | 2019-01-25 | 신라젠(주) | 종양 항원에 대한 항체의 생산 및 종양용해 우두 바이러스의 투여에 의한 종양 특이적 보체 의존적 세포독성의 생산 |
| WO2012122649A1 (en) * | 2011-03-15 | 2012-09-20 | Ottawa Hospital Research Institute | Recombinant orf virus |
| CN114262690A (zh) | 2011-04-15 | 2022-04-01 | 吉恩勒克斯公司 | 减毒的痘苗病毒的克隆毒株及其使用方法 |
| EP2764119A2 (en) | 2011-10-05 | 2014-08-13 | Genelux Corporation | Method for detecting replication or colonization of a biological therapeutic |
| DK2968281T3 (da) | 2013-03-13 | 2020-11-02 | Univ Texas | Mtor-hæmmere til forebyggelse af vækst af tarmpolyp |
| CA2903582C (en) | 2013-03-14 | 2021-06-08 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| DE102013105144A1 (de) * | 2013-05-17 | 2014-11-20 | Arno Thaller | Pharmazeutisches Kombinationspräparat mit einem anti-idiotypischen Antikörperfragment |
| CA2933908C (en) | 2013-12-31 | 2024-01-30 | Rapamycin Holdings, Llc | Oral rapamycin nanoparticle preparations and use |
| US9700544B2 (en) | 2013-12-31 | 2017-07-11 | Neal K Vail | Oral rapamycin nanoparticle preparations |
| NZ732211A (en) | 2014-10-24 | 2020-04-24 | Calidi Biotherapeutics Inc | Combination immunotherapy approach for treatment of cancer |
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| WO2016168862A1 (en) | 2015-04-17 | 2016-10-20 | Memorial Sloan-Kettering Cancer Center | Use of mva or mvadeltae3l as immunotherapeutic agents against solid tumors |
| CN115212301A (zh) | 2015-08-11 | 2022-10-21 | 卡利迪生物治疗有限公司 | 用以癌症治疗的天花疫苗 |
| US10612005B2 (en) | 2016-01-08 | 2020-04-07 | Replimune Limited | Modified oncolytic virus |
| CN105754952B (zh) * | 2016-02-16 | 2020-07-10 | 中国农业科学院兰州兽医研究所 | 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用 |
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| KR20180133395A (ko) | 2016-02-25 | 2018-12-14 | 메모리얼 슬로안 케터링 캔서 센터 | 암 면역요법을 위한, 인간 flt3l 또는 gm-csf의 발현이 있거나 없으며 티미딘 키나제가 결실된 복제 가능 약독화 백시니아 바이러스 |
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| US10842835B2 (en) | 2016-05-25 | 2020-11-24 | Arizona Board Of Regents On Behalf Of Arizona State University | Oncolytic vaccinia virus mutants and using same for cancer treatment |
| CN109844104B (zh) * | 2016-07-21 | 2023-04-28 | 可隆生命科学株式会社 | 重组疫苗病毒及其用途 |
| WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
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| US11242509B2 (en) | 2017-05-12 | 2022-02-08 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
| US10610583B2 (en) | 2017-08-31 | 2020-04-07 | Regents Of The University Of Minnesota | Methods and compositions for treating glioma and medulloblastoma brain tumors using the zika virus |
| CA3088609C (en) * | 2018-01-19 | 2024-02-13 | Kolon Life Science, Inc. | Recombinant vaccinia virus and pharmaceutical composition comprising same |
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| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| CA2051289C (en) | 1990-09-14 | 2002-11-26 | Robert L. Martuza | Viral mediated destruction of neoplastic cells |
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| JPH1087503A (ja) | 1996-09-06 | 1998-04-07 | Nippon Chem Res Kk | 神経系腫瘍細胞のアポトーシス剤 |
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- 2000-11-08 BR BR0015491-1A patent/BR0015491A/pt not_active Application Discontinuation
- 2000-11-08 AU AU12626/01A patent/AU782020B2/en not_active Expired
- 2000-11-09 US US09/708,663 patent/US6596268B1/en not_active Expired - Lifetime
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2001
- 2001-09-28 US US09/965,294 patent/US6649157B2/en not_active Expired - Lifetime
-
2002
- 2002-12-03 HK HK02108779.8A patent/HK1047698A1/zh unknown
-
2003
- 2003-04-18 US US10/418,290 patent/US7252817B2/en not_active Expired - Lifetime
-
2006
- 2006-11-07 US US11/557,467 patent/US7731951B2/en not_active Expired - Fee Related
-
2007
- 2007-05-30 US US11/807,920 patent/US7964186B2/en not_active Expired - Fee Related
- 2007-05-30 US US11/807,906 patent/US7582289B2/en not_active Expired - Lifetime
- 2007-05-30 US US11/807,770 patent/US7799329B2/en not_active Expired - Fee Related
-
2010
- 2010-04-16 US US12/761,534 patent/US8080241B2/en not_active Expired - Fee Related
-
2011
- 2011-11-16 US US13/297,384 patent/US8491886B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7799329B2 (en) | 2010-09-21 |
| HK1047698A1 (zh) | 2003-03-07 |
| US20120156168A1 (en) | 2012-06-21 |
| US6649157B2 (en) | 2003-11-18 |
| CA2388807A1 (en) | 2001-05-25 |
| CA2388807C (en) | 2013-08-06 |
| US20100203147A1 (en) | 2010-08-12 |
| AU1262601A (en) | 2001-05-30 |
| US7964186B2 (en) | 2011-06-21 |
| US20080019981A1 (en) | 2008-01-24 |
| US8080241B2 (en) | 2011-12-20 |
| US7582289B2 (en) | 2009-09-01 |
| WO2001035970A1 (en) | 2001-05-25 |
| US8491886B2 (en) | 2013-07-23 |
| US20020028195A1 (en) | 2002-03-07 |
| US7252817B2 (en) | 2007-08-07 |
| US20080019980A1 (en) | 2008-01-24 |
| BR0015491A (pt) | 2002-10-15 |
| EP1955703A1 (en) | 2008-08-13 |
| MXPA02004736A (es) | 2003-01-28 |
| AU782020B2 (en) | 2005-06-30 |
| US20070086984A1 (en) | 2007-04-19 |
| JP2003514024A (ja) | 2003-04-15 |
| US20040057929A1 (en) | 2004-03-25 |
| CA2720361A1 (en) | 2001-05-25 |
| US6596268B1 (en) | 2003-07-22 |
| US20080031886A1 (en) | 2008-02-07 |
| NZ518454A (en) | 2004-07-30 |
| US7731951B2 (en) | 2010-06-08 |
| EP1227828A1 (en) | 2002-08-07 |
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