ZA200108259B - Combinations of gaba analogs and tricyclic compounds to treat depression. - Google Patents

Combinations of gaba analogs and tricyclic compounds to treat depression.

Info

Publication number
ZA200108259B
ZA200108259B ZA200108259A ZA200108259A ZA200108259B ZA 200108259 B ZA200108259 B ZA 200108259B ZA 200108259 A ZA200108259 A ZA 200108259A ZA 200108259 A ZA200108259 A ZA 200108259A ZA 200108259 B ZA200108259 B ZA 200108259B
Authority
ZA
South Africa
Prior art keywords
combinations
tricyclic compounds
treat depression
gaba analogs
gaba
Prior art date
Application number
ZA200108259A
Other languages
English (en)
Inventor
Leslie Magnus
Douglas Saltel
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA200108259B publication Critical patent/ZA200108259B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200108259A 1999-04-09 2001-10-08 Combinations of gaba analogs and tricyclic compounds to treat depression. ZA200108259B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12857199P 1999-04-09 1999-04-09

Publications (1)

Publication Number Publication Date
ZA200108259B true ZA200108259B (en) 2003-03-26

Family

ID=22435960

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200108259A ZA200108259B (en) 1999-04-09 2001-10-08 Combinations of gaba analogs and tricyclic compounds to treat depression.

Country Status (11)

Country Link
EP (1) EP1180058A1 (fr)
JP (1) JP2002541224A (fr)
KR (1) KR20010108466A (fr)
AU (1) AU3492900A (fr)
CA (1) CA2367494A1 (fr)
HU (1) HUP0200733A3 (fr)
IL (1) IL145736A0 (fr)
NZ (1) NZ514401A (fr)
TR (1) TR200102850T2 (fr)
WO (1) WO2000061234A1 (fr)
ZA (1) ZA200108259B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL126999A (en) 1996-07-24 2002-03-10 Warner Lambert Co Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
AU2003210486B2 (en) * 2002-01-16 2007-06-28 Endo Pharmaceuticals Inc. Pharmaceutical composition and method for treating disorders of the central nervous system
CA2537402C (fr) * 2003-09-12 2009-05-05 Pfizer Inc. Associations comprenant des ligands alpha-2-delta et des inhibiteurs du recaptage de la serotonine et de la noradrenaline
EP1675582A1 (fr) * 2003-09-12 2006-07-05 Warner-Lambert Company LLC Combinaison comportant un ligand alpha-2-delta et un inhibiteur selectif du recaptage de la serotonine et/ou un inhibiteur selectif du recaptage de la noradrenaline et permettant le traitement de la depression et des troubles anxieux

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2410821A1 (de) * 1974-03-07 1975-09-18 Hoechst Ag Pharmazeutische kombinationspraeparate mit psychotroper wirkung und verfahren zu ihrer herstellung
FR2453643A2 (fr) * 1977-06-24 1980-11-07 Synthelabo Compositions pharmaceutiques actives sur le systeme nerveux central
US5025035A (en) * 1990-10-12 1991-06-18 Warner-Lambert Company Method of treating depression
WO1992009560A1 (fr) * 1990-11-27 1992-06-11 Northwestern University Analogues de l'acide gamma-aminobutyrique (gaba) et de l'acide l-glutamique utilises dans le traitement contre les attaques
EP0726073A3 (fr) * 1995-02-10 1998-07-08 Eduardo Samuel Bleiweiss Compositions pharmaceutique contenant au moins un composé choisi parmi le haloperidol, imipramine et le trifluoroperazine

Also Published As

Publication number Publication date
HUP0200733A3 (en) 2003-04-28
HUP0200733A2 (hu) 2002-07-29
JP2002541224A (ja) 2002-12-03
TR200102850T2 (tr) 2002-03-21
CA2367494A1 (fr) 2000-10-19
AU3492900A (en) 2000-11-14
EP1180058A1 (fr) 2002-02-20
WO2000061234A1 (fr) 2000-10-19
KR20010108466A (ko) 2001-12-07
NZ514401A (en) 2003-10-31
IL145736A0 (en) 2002-07-25

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